LCE1C and PLSCR3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LCE1C	PLSCR3
Description		late cornified envelope 1C	phospholipid scramblase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Mitochondrion Mitochondrial Inner Membrane Cytosol Plasma Membrane Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding	Magnesium Ion Binding Calcium Ion Binding Protein Binding SH3 Domain Binding Phospholipid Scramblase Activity Lead Ion Binding Mercury Ion Binding Calcium-dependent Protein Binding
	Biological Process	Epidermis Development Keratinization	Lipid Transport Apoptotic Process Mitochondrial Membrane Organization Plasma Membrane Phospholipid Scrambling Glucose Homeostasis Cholesterol Homeostasis Regulation Of Apoptotic Process Cellular Response To Lipopolysaccharide Regulation Of Release Of Cytochrome C From Mitochondria
Pathways		Formation of the cornified envelope
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		75 interacting genes: ADAMTSL4 ALPP CHIC2 CHRD CRCT1 CREB5 CYSRT1 EFEMP1 EFEMP2 FBLN1 GUCD1 HOXA1 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP2-3 KRTAP2-4 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE4A LCE5A MACO1 NECTIN2 NTAQ1 NTN4 NUTF2 ODF1 OIT3 OTX1 PLA2G10 PLAC8 PLSCR3 PLSCR4 POU4F2 PSMB1 SLC39A7 SPRED2 SPRY1 SPRY2 TGFB1 TRIM42 VASN VWC2 VWC2L	34 interacting genes: ACTMAP AIPL1 C10orf55 C22orf39 CATSPER1 COL8A1 HOXA1 INCA1 KRTAP11-1 KRTAP15-1 KRTAP19-6 KRTAP19-7 KRTAP3-2 KRTAP3-3 KRTAP6-1 LCE1C LCE2B LCE4A LCE5A MAPKBP1 NAA10 NXPE2 PITX1 PLSCR1 PRKCD RUNX1T1 S100A7L2 SMCP STK16 TNIP3 TNS2 TRIP13 WWOX ZIC1
Entrez ID		353133	57048
HPRD ID		13967	07400
Ensembl ID		ENSG00000197084	ENSG00000187838
Uniprot IDs		Q5T751	Q9NRY6
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Hair Cycle Negative Regulation Of Lens Fiber Cell Differentiation Identical Protein Binding Protein Binding Regulation Of Lens Fiber Cell Differentiation Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Branch Elongation Of An Epithelium Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Epithelial To Mesenchymal Transition Axis Elongation Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Regulation Of Epithelial To Mesenchymal Transition Elastic Fiber Negative Regulation Of Cellular Response To Growth Factor Stimulus Extracellular Matrix Assembly Negative Regulation Of ERK1 And ERK2 Cascade Bud Elongation Involved In Lung Branching Interstitial Matrix Regulation Of Cellular Response To Growth Factor Stimulus Basement Membrane	Intermediate Filament Keratinization
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?