LCE1C and KRTAP10-11

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid)

		LCE1C	KRTAP10-11
Description		late cornified envelope 1C	keratin associated protein 10-11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Epidermis Development Keratinization
Pathways		Formation of the cornified envelope	Keratinization Keratinization
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		75 interacting genes: ADAMTSL4 ALPP CHIC2 CHRD CRCT1 CREB5 CYSRT1 EFEMP1 EFEMP2 FBLN1 GUCD1 HOXA1 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP2-3 KRTAP2-4 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE4A LCE5A MACO1 NECTIN2 NTAQ1 NTN4 NUTF2 ODF1 OIT3 OTX1 PLA2G10 PLAC8 PLSCR3 PLSCR4 POU4F2 PSMB1 SLC39A7 SPRED2 SPRY1 SPRY2 TGFB1 TRIM42 VASN VWC2 VWC2L	63 interacting genes: ADAMTSL4 ANKS1A C22orf39 CAMK2B CATSPER1 CRCT1 CREB5 CYSRT1 FAM76B FBXO34 GLRX3 HOXA1 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP13-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP5-2 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A MEOX2 MOBP NBPF19 NOTCH2NLA NUFIP2 OTX1 PLSCR1 POU4F2 PRKAB2 PRKAG1 SMCP SPATA3 SPRY1 SPRY2 TLE5 ZNF587
Entrez ID		353133	386678
HPRD ID		13967	11186
Ensembl ID		ENSG00000197084	ENSG00000243489
Uniprot IDs		Q5T751	P60411 P60412
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Hair Cycle Negative Regulation Of Lens Fiber Cell Differentiation Identical Protein Binding Protein Binding Regulation Of Lens Fiber Cell Differentiation Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Branch Elongation Of An Epithelium Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Epithelial To Mesenchymal Transition Axis Elongation Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Regulation Of Epithelial To Mesenchymal Transition Elastic Fiber Negative Regulation Of Cellular Response To Growth Factor Stimulus Extracellular Matrix Assembly Negative Regulation Of ERK1 And ERK2 Cascade Bud Elongation Involved In Lung Branching Interstitial Matrix Regulation Of Cellular Response To Growth Factor Stimulus Basement Membrane	Keratinization Intermediate Filament Epidermis Development Keratin Filament Tissue Development Hair Cycle Identical Protein Binding Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Lens Fiber Cell Differentiation AMP-activated Protein Kinase Activity Protein Binding Bud Elongation Involved In Lung Branching Developmental Process Regulation Of Lens Fiber Cell Differentiation Nucleotide-activated Protein Kinase Complex Regulation Of Neurotrophin TRK Receptor Signaling Pathway Branch Elongation Of An Epithelium
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