SEPTIN14 and VPS25

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SEPTIN14	VPS25
Description		septin 14	vacuolar protein sorting 25 homolog
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GO Annotations	Cellular Component	Acrosomal Vesicle Cytoplasm Cytoskeleton Septin Ring Microtubule Cytoskeleton Axon Dendrite Septin Complex Cytoplasmic Vesicle Cell Division Site Cell Projection Perikaryon Perinuclear Region Of Cytoplasm	ESCRT II Complex Nucleus Nucleoplasm Cytoplasm Endosome Cytosol Endosome Membrane Membrane Extracellular Exosome
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Molecular Adaptor Activity	Structural Molecule Activity Protein Binding Protein Homodimerization Activity
	Biological Process	Neuron Migration Spermatid Development Intracellular Protein Localization Cell Division Cytoskeleton-dependent Cytokinesis Protein Localization To Perinuclear Region Of Cytoplasm	Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Protein Transport Macroautophagy Multivesicular Body Assembly Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Multivesicular Body Sorting Pathway Membrane Fission
Pathways			Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events
Drugs
Diseases
GWAS
Interacting Genes		6 interacting genes: ARMC7 CEBPA FAM124B GORASP2 NTAQ1 VPS25	24 interacting genes: APIP ASPG B9D2 BEND5 BPIFA1 CHMP6 CRLF3 EIF4G3 GPR35 LTB4R2 PICK1 REL RHOXF2 SDCBP2 SEPTIN14 SNCA SNF8 SPG21 SPRY2 SYCE1 TADA2A TRIM27 UBC VPS36
Entrez ID		346288	84313
HPRD ID		16972	14396
Ensembl ID		ENSG00000154997	ENSG00000131475
Uniprot IDs		Q6ZU15	Q9BRG1
PDB IDs		8SJJ	2ZME 3CUQ 3HTU
Enriched GO Terms of Interacting Partners?			Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Organization ESCRT II Complex Multivesicular Body Assembly Late Endosome To Vacuole Transport Endosome Transport Via Multivesicular Body Sorting Pathway Membrane Fission Multivesicular Body Sorting Pathway Lipid Binding Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Endosome Organization Regulation Of Exosomal Secretion Negative Regulation Of Autophagy Endosomal Transport
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