IFIT3 and RAD23A

Number of citations of the paper that reports this interaction (PMID 21163940)
13

Data Source:
BioGRID (two hybrid)

		IFIT3	RAD23A
Gene Name		interferon-induced protein with tetratricopeptide repeats 3	RAD23 homolog A (S. cerevisiae)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol	Proteasome Complex Nucleoplasm Cytoplasm
	Molecular Function	Molecular_function Protein Binding Identical Protein Binding	Damaged DNA Binding Single-stranded DNA Binding Protein Binding Polyubiquitin Binding Ubiquitin-specific Protease Binding
	Biological Process	Negative Regulation Of Cell Proliferation Response To Virus Cytokine-mediated Signaling Pathway Cellular Response To Interferon-alpha Negative Regulation Of Apoptotic Process Defense Response To Virus Type I Interferon Signaling Pathway	Nucleotide-excision Repair Viral Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Viral Genome Replication
Pathways		Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: A2M APOE AQPEP CCDC67 CDC37 CYP2C8 ECSIT FANCA HAUS1 IFIT1 IFIT2 IFIT5 LONP1 MAST1 PSEN2 RAD23A RNF32 TMEM183A TPM3	50 interactors: A2M ADRM1 ANKRD40 ATXN3 ATXN7 CCNA2 CCNB1 CDC37 CREBBP DBI ECSIT EP300 EWSR1 FAM188A FILIP1 GTF2H1 IFIT3 IFIT5 LOXL4 MAST1 MDM2 MPG NGLY1 PARK2 PDE6D PHAX PI4K2A PSEN1 PSMC5 PSMD4 RNF115 RNF32 RPN1 SQSTM1 TRAF2 TRAF5 TRIM54 TRIP6 UBB UBE2D1 UBE2L3 UBE2L6 UBE3A UBL7 UBQLN4 USP25 VAV2 XPC ZBTB44 ZBTB8A
Entrez ID		3437	5886
HPRD ID		05228	07191
Ensembl ID		ENSG00000119917	ENSG00000179262
Uniprot IDs		O14879 Q5T765	A8K1J3 P54725
PDB IDs			1DV0 1F4I 1IFY 1OQY 1P98 1P9D 1QZE 1TP4 1ZO6 2WYQ
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Binding Response To Stress Negative Regulation Of Binding Positive Regulation Of Viral Genome Replication Regulation Of Protein Binding Defense Response To Virus Regulation Of Binding Oxidation-dependent Protein Catabolic Process Positive Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Positive Regulation Of Dendritic Spine Maintenance Negative Regulation Of Dendritic Spine Maintenance Negative Regulation Of Phospholipid Efflux Negative Regulation Of Lipid Transport Across Blood Brain Barrier Positive Regulation Of Lipid Transport Across Blood Brain Barrier Positive Regulation Of Postsynaptic Membrane Organization Negative Regulation Of Postsynaptic Membrane Organization Response To Virus Response To External Stimulus Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Cellular Component Assembly Regulation Of Oxidoreductase Activity Positive Regulation Of Neurofibrillary Tangle Assembly Negative Regulation Of Complement Activation, Lectin Pathway Negative Regulation Of Presynaptic Membrane Organization Positive Regulation Of Presynaptic Membrane Organization Cellular Response To Stimulus Immune Response Innate Immune Response Negative Regulation Of Helicase Activity Positive Regulation Of Phospholipid Efflux Negative Regulation Of Cholesterol Biosynthetic Process Regulation Of Mitochondrial DNA Replication Regulation Of Postsynaptic Membrane Organization Very-low-density Lipoprotein Particle Clearance Response To Stimulus Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Microtubule Organizing Center Organization Multi-ciliated Epithelial Cell Differentiation Response To Type I Interferon Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Regulation Of Tau-protein Kinase Activity Response To Aluminum Ion Negative Regulation Of Cholesterol Efflux N-methyl-D-aspartate Receptor Clustering Intracellular Transport Of Viral Protein In Host Cell Regulation Of Presynaptic Membrane Organization Organelle Organization Negative Regulation Of Dendritic Spine Development	Cellular Macromolecule Catabolic Process Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteolysis Catabolic Process Protein Polyubiquitination Regulation Of Protein Catabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Protein Metabolic Process Cellular Response To Stress Response To Stress Cellular Protein Modification Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Protein Ubiquitination Positive Regulation Of Ligase Activity Positive Regulation Of Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Mitotic Cell Cycle Checkpoint Mitotic DNA Damage Checkpoint Proteasomal Protein Catabolic Process Cell Cycle Phase Transition Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Mitotic DNA Integrity Checkpoint Cellular Response To Oxygen Levels Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Negative Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Catalytic Activity Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Cellular Protein Metabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Cycle Phase Transition Innate Immune Response
Tagcloud ?		adenovirus apobec3a ddx58 exact expand hiv ifi27 ifi44l ifit1 ifit2 innate irf7 isg15 isg20 isgs mdms microarray monocyte mx1 mx2 reservoirs rig rsad2 select stat1 tnfsf10 trail viperin vpr	2h5 accompanies anova dynactin gadd45a gtf2h5 invites keuls macaques malfunctioning nbn1 ndd ndds newman ovx perimenopausal presenilin1 proteosome psen1 raphe scna serotonin speculation subserving symptomology ube2d3 ube3a ubea5 ubiquinase
Tagcloud (Difference) ?		adenovirus apobec3a ddx58 exact expand hiv ifi27 ifi44l ifit1 ifit2 innate irf7 isg15 isg20 isgs mdms microarray monocyte mx1 mx2 reservoirs rig rsad2 select stat1 tnfsf10 trail viperin vpr	2h5 accompanies anova dynactin gadd45a gtf2h5 invites keuls macaques malfunctioning nbn1 ndd ndds newman ovx perimenopausal presenilin1 proteosome psen1 raphe scna serotonin speculation subserving symptomology ube2d3 ube3a ubea5 ubiquinase
Tagcloud (Intersection) ?