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RAD23A and GTF2H1
Number of citations of the paper that reports this interaction (PMID
14706819
)
6
Data Source:
BioGRID
(pull down)
RAD23A
GTF2H1
Gene Name
RAD23 homolog A (S. cerevisiae)
general transcription factor IIH, polypeptide 1, 62kDa
Image
Gene Ontology Annotations
Cellular Component
Proteasome Complex
Nucleoplasm
Cytoplasm
Core TFIIH Complex
Nucleoplasm
Holo TFIIH Complex
Molecular Function
Damaged DNA Binding
Single-stranded DNA Binding
Protein Binding
Polyubiquitin Binding
Ubiquitin-specific Protease Binding
Protein Kinase Activity
Protein Binding
DNA-dependent ATPase Activity
RNA Polymerase II Carboxy-terminal Domain Kinase Activity
Biological Process
Nucleotide-excision Repair
Viral Process
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Viral Genome Replication
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Nucleotide-excision Repair, DNA Damage Removal
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair
Transcription From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Protein Phosphorylation
Gene Expression
Viral Process
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Viral Transcription
Pathways
RNA Polymerase II Promoter Escape
Formation of HIV-1 elongation complex containing HIV-1 Tat
Nucleotide Excision Repair
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Chain Elongation
RNA Polymerase II Transcription
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Clearance
HIV Infection
Formation of the Early Elongation Complex
Tat-mediated elongation of the HIV-1 transcript
Formation of transcription-coupled NER (TC-NER) repair complex
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II Pre-transcription Events
Dual incision reaction in TC-NER
NoRC negatively regulates rRNA expression
HIV Transcription Initiation
HIV Life Cycle
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II HIV Promoter Escape
HIV Transcription Elongation
Dual incision reaction in GG-NER
mRNA Capping
RNA Polymerase I Transcription
RNA Polymerase I Promoter Escape
RNA Polymerase I Transcription Termination
Epigenetic regulation of gene expression
Negative epigenetic regulation of rRNA expression
Late Phase of HIV Life Cycle
Formation of RNA Pol II elongation complex
Global Genomic NER (GG-NER)
RNA Polymerase II Transcription Initiation And Promoter Clearance
Transcription-coupled NER (TC-NER)
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
Formation of incision complex in GG-NER
RNA Polymerase II Transcription Initiation
Transcription of the HIV genome
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Amyloid A Levels (
21124955
)
Pancreatic cancer (
23180869
)
Protein-Protein Interactions
50 interactors:
A2M
ADRM1
ANKRD40
ATXN3
ATXN7
CCNA2
CCNB1
CDC37
CREBBP
DBI
ECSIT
EP300
EWSR1
FAM188A
FILIP1
GTF2H1
IFIT3
IFIT5
LOXL4
MAST1
MDM2
MPG
NGLY1
PARK2
PDE6D
PHAX
PI4K2A
PSEN1
PSMC5
PSMD4
RNF115
RNF32
RPN1
SQSTM1
TRAF2
TRAF5
TRIM54
TRIP6
UBB
UBE2D1
UBE2L3
UBE2L6
UBE3A
UBL7
UBQLN4
USP25
VAV2
XPC
ZBTB44
ZBTB8A
42 interactors:
ACTN1
AR
ATF7IP
BRPF1
CCNH
CCSER2
CDK7
CTD
E2F1
ERCC2
ERCC3
ERCC4
ERCC5
ESR1
FUBP1
GTF2E1
GTF2E2
GTF2H2
GTF2H3
HNF4A
HNRNPU
HOXC11
JDP2
KIF13A
KPNA3
MCM2
MMS19
PIK3R1
PLCG1
POU2AF1
PSMC2
RAD23A
REEP5
RXRB
TNIP1
TP53
TRIOBP
TXNRD2
USHBP1
XPA
XPC
ZSCAN1
Entrez ID
5886
2965
HPRD ID
07191
01807
Ensembl ID
ENSG00000179262
ENSG00000110768
Uniprot IDs
A8K1J3
P54725
P32780
PDB IDs
1DV0
1F4I
1IFY
1OQY
1P98
1P9D
1QZE
1TP4
1ZO6
2WYQ
1PFJ
2DII
2RNR
Enriched GO Terms of Interacting Partners
?
Cellular Macromolecule Catabolic Process
Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Proteolysis
Catabolic Process
Protein Polyubiquitination
Regulation Of Protein Catabolic Process
Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Ubiquitination
Positive Regulation Of Proteolysis
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Regulation Of Protein Metabolic Process
Cellular Response To Stress
Response To Stress
Cellular Protein Modification Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Ligase Activity
Positive Regulation Of Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Mitotic Cell Cycle Checkpoint
Mitotic DNA Damage Checkpoint
Proteasomal Protein Catabolic Process
Cell Cycle Phase Transition
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Mitotic DNA Integrity Checkpoint
Cellular Response To Oxygen Levels
Proteolysis
Regulation Of Proteasomal Protein Catabolic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Negative Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Regulation Of Catalytic Activity
Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of Mitotic Cell Cycle
Cellular Protein Metabolic Process
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Cell Cycle Phase Transition
Innate Immune Response
Nucleotide-excision Repair, DNA Damage Removal
Nucleotide-excision Repair
Transcription Initiation From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
Transcription-coupled Nucleotide-excision Repair
Viral Process
Cellular Response To DNA Damage Stimulus
Transcription From RNA Polymerase II Promoter
DNA Catabolic Process
Transcription Elongation From RNA Polymerase II Promoter
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Transcription, DNA-templated
Positive Regulation Of Gene Expression
Response To UV
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
DNA-templated Transcription, Elongation
Positive Regulation Of Cellular Biosynthetic Process
RNA Biosynthetic Process
Termination Of RNA Polymerase I Transcription
Gene Expression
Transcription Elongation From RNA Polymerase I Promoter
Nitrogen Compound Metabolic Process
DNA Repair
Transcription Initiation From RNA Polymerase I Promoter
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Transcription, DNA-templated
7-methylguanosine MRNA Capping
Transcription From RNA Polymerase I Promoter
7-methylguanosine RNA Capping
Positive Regulation Of Viral Process
DNA Metabolic Process
RNA Metabolic Process
Cellular Response To Stress
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Positive Regulation Of Viral Transcription
Regulation Of Viral Process
Nucleotide-excision Repair, DNA Incision
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Metabolic Process
Regulation Of Viral Transcription
Response To Stress
Tagcloud
?
2h5
accompanies
anova
dynactin
gadd45a
gtf2h5
invites
keuls
macaques
malfunctioning
nbn1
ndd
ndds
newman
ovx
perimenopausal
presenilin1
proteosome
psen1
raphe
scna
serotonin
speculation
subserving
symptomology
ube2d3
ube3a
ubea5
ubiquinase
Tagcloud (Difference)
?
2h5
accompanies
anova
dynactin
gadd45a
gtf2h5
invites
keuls
macaques
malfunctioning
nbn1
ndd
ndds
newman
ovx
perimenopausal
presenilin1
proteosome
psen1
raphe
scna
serotonin
speculation
subserving
symptomology
ube2d3
ube3a
ubea5
ubiquinase
Tagcloud (Intersection)
?