RAD23A and PSMD4

Number of citations of the paper that reports this interaction (PubMedID 12970176)
46

Data Source:
HPRD (in vivo, in vitro)

		RAD23A	PSMD4
Description		RAD23 nucleotide excision repair protein A	proteasome 26S subunit ubiquitin receptor, non-ATPase 4
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GO Annotations	Cellular Component	Proteasome Complex Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Protein-containing Complex	Proteasome Complex Nucleus Nucleoplasm Cytosol Proteasome Regulatory Particle, Base Subcomplex Proteasome Accessory Complex
	Molecular Function	Damaged DNA Binding Single-stranded DNA Binding Protein Binding Kinase Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding Proteasome Binding Ubiquitin-specific Protease Binding	RNA Binding Protein Binding Polyubiquitin Modification-dependent Protein Binding Identical Protein Binding Molecular Adaptor Activity
	Biological Process	DNA Repair Nucleotide-excision Repair DNA Damage Response Protein Destabilization Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Viral Genome Replication Positive Regulation Of Cell Cycle	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		Josephin domain DUBs DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER	Proteasome assembly Proteasome assembly
Drugs
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353)	Body mass index ( 26426971) Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		79 interacting genes: A2M ADRM1 ANKRD40 ATXN3 ATXN7 CCNA2 CDC37 CEBPA CHEK1 CNTROB CREBBP DAZAP2 DBI ECSIT EP300 EWSR1 FILIP1 GTF2H1 H4C1 HSPB1 IFIT3 IFIT5 KRTAP12-2 LOXL4 MAP3K1 MAST1 MDM2 MINDY3 MKRN1 MPG NEDD8 NGLY1 NUTM2F OGT PDE6D PHAX PI4K2A PRKN PSEN1 PSMC5 PSMD4 RABGEF1 REL RNF115 RNF32 RNF41 RPN1 RPS27A SH3RF1 SMURF1 SQSTM1 TNFAIP3 TRAF2 TRAF3 TRAF5 TRAF6 TRIM39 TRIM50 TRIM54 TRIM55 TRIM8 TRIP6 UBA52 UBB UBC UBE3A UBE4B UBL7 UBQLN4 UBXN1 UIMC1 USP25 VAV2 WWP2 XPC ZBTB26 ZBTB44 ZBTB8A ZFAND6	46 interacting genes: ADRM1 APP BTRC CCNA2 CFTR CUL1 EGFR FBXO25 FLOT1 GNB5 H2AC4 H2BC3 ID1 MAP3K1 MDM2 MYOD1 NEDD4 NEDD4L NEDD8 NUB1 OGT PRKN PTEN RAD23A RAD23B RASSF8 RBCK1 RBM11 SCHIP1 SIAH2 SMURF1 SREBF2 STUB1 TCF3 TCP11L1 TMEM129 TP53 TRIM63 UBB UBC UBD UBE2C UBQLN1 UBQLN2 WWP2 XPC
Entrez ID		5886	5710
HPRD ID		07191	03386
Ensembl ID		ENSG00000179262	ENSG00000159352
Uniprot IDs		A8K1J3 P54725	P55036 Q5VWC4
PDB IDs		1DV0 1F4I 1IFY 1OQY 1P98 1P9D 1QZE 1TP4 2WYQ 5XBO 6W2G 6W2H 6W2I 6XQI 6XQJ 7TGP 8Q06	1P9C 1P9D 1UEL 1YX4 1YX5 1YX6 2KDE 2KDF 5GJQ 5GJR 5L4K 5LN3 5M32 5T0C 5T0G 5T0H 5T0I 5T0J 5VFP 5VFQ 5VFR 5VFS 5VFT 5VFU 5VGZ 5VHF 5VHH 5VHI 5VHS 6MSB 6MSD 6MSE 6MSG 6MSH 6MSJ 6MSK 6MUN 6U19 6WJD 6WJN 7QXN 7QXP 7QXU 7QXW 7QXX 7QY7 7QYA 7QYB 7W37 7W38 7W39 7W3A 7W3B 7W3C 7W3F 7W3G 7W3H 7W3I 7W3J 7W3K 7W3M 8CVT 8JRI 8JRT 8JTI 8K0G 8USB 8USC 9E8G 9E8H 9E8I 9E8J 9E8K 9E8L 9E8N 9E8O 9E8Q
Enriched GO Terms of Interacting Partners?		Post-translational Protein Modification Ubiquitin Protein Ligase Activity Protein Ubiquitination Protein Modification Process Protein Modification By Small Protein Conjugation Cytosol Protein Polyubiquitination Protein Autoubiquitination Modification-dependent Protein Catabolic Process Regulation Of Proteolysis Protein Metabolic Process Proteolysis Involved In Protein Catabolic Process Ubiquitin Protein Ligase Binding Regulation Of Proteasomal Protein Catabolic Process Proteolysis Macromolecule Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Zinc Ion Binding Regulation Of Protein Metabolic Process Protein K63-linked Ubiquitination Ubiquitin-protein Transferase Activity Cytoplasm Regulation Of Canonical NF-kappaB Signal Transduction Ubiquitin-dependent Protein Catabolic Process Protein Tag Activity Macromolecule Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Intracellular Signal Transduction Protein Catabolic Process Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Regulation Of Signal Transduction Protein K48-linked Deubiquitination CD40 Receptor Complex Transferase Activity Regulation Of Intracellular Signal Transduction Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Catabolic Process Canonical NF-kappaB Signal Transduction Positive Regulation Of Proteolysis Ubiquitin Binding Positive Regulation Of Protein Catabolic Process Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Immune Response-regulating Cell Surface Receptor Signaling Pathway Polyubiquitin Modification-dependent Protein Binding Identical Protein Binding Protein Binding Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Signaling	Modification-dependent Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Proteasomal Protein Catabolic Process Protein Modification By Small Protein Conjugation Proteolysis Macromolecule Catabolic Process Post-translational Protein Modification Regulation Of Proteolysis Protein Catabolic Process Protein Modification Process Regulation Of Protein Catabolic Process Protein Metabolic Process Positive Regulation Of Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Catabolic Process Ubiquitin-protein Transferase Activity Regulation Of Proteasomal Protein Catabolic Process Ubiquitin Protein Ligase Activity Protein Polyubiquitination Positive Regulation Of Protein Metabolic Process Macromolecule Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Catabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Nucleus Cytosol Ubiquitin Protein Ligase Binding Positive Regulation Of Macromolecule Metabolic Process Nucleoplasm Positive Regulation Of Metabolic Process Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Primary Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Enzyme Binding Proteasome Binding Cytoplasm Cellular Response To Stress Protein-folding Chaperone Binding Ubiquitin Binding Regulation Of Metabolic Process Negative Regulation Of Potassium Ion Export Across Plasma Membrane Protein Monoubiquitination Ubiquitin Ligase Complex Regulation Of Signal Transduction Protein Destabilization
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