IFIT3 and DEUP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		IFIT3	DEUP1
Description		interferon induced protein with tetratricopeptide repeats 3	deuterosome assembly protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol	Cytoplasm Centriole Deuterosome
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Immune System Process Negative Regulation Of Cell Population Proliferation Response To Virus Negative Regulation Of Apoptotic Process Innate Immune Response Defense Response To Virus Antiviral Innate Immune Response	Centriole Replication Cell Projection Organization De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation Multi-ciliated Epithelial Cell Differentiation
Pathways		Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Hormone measurements ( 30576415)
Interacting Genes		21 interacting genes: A2M ANXA1 APOE CYP2C8 DEUP1 ECSIT FANCA HAUS1 IFIT1 IFIT1B IFIT2 IFIT5 LONP1 LVRN MAST1 PSEN2 RAD23A RNF32 TMEM183A TPM1 TPM3	44 interacting genes: AMPH ARL16 BRMS1L CCDC187 CCDC85B CCHCR1 CEP57 DGCR6 DGCR6L DTNB ESRRG EXOC5 FAM50B FBF1 GEM GOLGA2 HAUS8 HGS IFIT3 ING5 KCTD9 KIFC3 KRT15 KRT28 KRT3 LNX1 NTAQ1 PIAS2 PPP1R13B RUNX1T1 SKIL SUMO1 TBC1D22B TFPT TRIM54 TXLNA TXLNB USHBP1 ZFHX3 ZNF148 ZNF460 ZNF572 ZNF655 ZNF835
Entrez ID		3437	159989
HPRD ID		05228	08689
Ensembl ID		ENSG00000119917	ENSG00000165325
Uniprot IDs		A0A7P0T7D6 O14879 Q5T765	E9PLX9 Q05D60
PDB IDs		6C6K
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Viral Translation RNA Sequestering Activity Muscle Thin Filament Tropomyosin Regulation Of Viral Process Response To Stress Negative Regulation Of Viral Process Regulation Of Viral Genome Replication Actin Filament Amyloid Precursor Protein Metabolic Process Defense Response To Virus Regulation Of Viral Life Cycle Innate Immune Response Negative Regulation Of Phospholipid Efflux Negative Regulation Of Postsynaptic Membrane Organization Positive Regulation Of Lipid Transport Across Blood-brain Barrier Negative Regulation Of Lipid Transport Across Blood-brain Barrier Regulation Of Cellular Response To Very-low-density Lipoprotein Particle Stimulus Metal Chelating Activity Intermediate-density Lipoprotein Particle Clearance Response To Virus Positive Regulation Of Viral Genome Replication Positive Regulation Of Heart Rate By Epinephrine Oxidation-dependent Protein Catabolic Process	Microtubule Binding Keratin Filament
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