IFIT1 and IFIT3

Number of citations of the paper that reports this interaction (PubMedID 30833792)
0

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		IFIT1	IFIT3
Description		interferon induced protein with tetratricopeptide repeats 1	interferon induced protein with tetratricopeptide repeats 3
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GO Annotations	Cellular Component	Cytoplasm Cytosol Host Cell	Cytoplasm Mitochondrion Cytosol
	Molecular Function	RNA Binding Enzyme Inhibitor Activity Protein Binding RNA Sequestering Activity	Protein Binding Identical Protein Binding
	Biological Process	Immune System Process Response To Virus Intracellular Transport Of Viral Protein In Host Cell Positive Regulation Of Viral Genome Replication Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Response To Other Organism Cellular Response To Type I Interferon Cellular Response To Exogenous DsRNA Antiviral Innate Immune Response Negative Regulation Of Viral Translation	Immune System Process Negative Regulation Of Cell Population Proliferation Response To Virus Negative Regulation Of Apoptotic Process Innate Immune Response Defense Response To Virus Antiviral Innate Immune Response
Pathways		ISG15 antiviral mechanism Interferon alpha/beta signaling	Interferon alpha/beta signaling
Drugs
Diseases
GWAS			Hormone measurements ( 30576415)
Interacting Genes		5 interacting genes: ANXA1 EIF3E IFIT2 IFIT3 WEE2-AS1	21 interacting genes: A2M ANXA1 APOE CYP2C8 DEUP1 ECSIT FANCA HAUS1 IFIT1 IFIT1B IFIT2 IFIT5 LONP1 LVRN MAST1 PSEN2 RAD23A RNF32 TMEM183A TPM1 TPM3
Entrez ID		3434	3437
HPRD ID		00983	05228
Ensembl ID		ENSG00000185745	ENSG00000119917
Uniprot IDs		P09914	A0A7P0T7D6 O14879 Q5T765
PDB IDs		4HOU 5UDI 5UDJ 5UDK 5UDL 5W5H 5W5I 6C6K	6C6K
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Viral Translation RNA Sequestering Activity Muscle Thin Filament Tropomyosin Regulation Of Viral Process Response To Stress Negative Regulation Of Viral Process Regulation Of Viral Genome Replication Actin Filament Amyloid Precursor Protein Metabolic Process Defense Response To Virus Regulation Of Viral Life Cycle Innate Immune Response Negative Regulation Of Phospholipid Efflux Negative Regulation Of Postsynaptic Membrane Organization Positive Regulation Of Lipid Transport Across Blood-brain Barrier Negative Regulation Of Lipid Transport Across Blood-brain Barrier Regulation Of Cellular Response To Very-low-density Lipoprotein Particle Stimulus Metal Chelating Activity Intermediate-density Lipoprotein Particle Clearance Response To Virus Positive Regulation Of Viral Genome Replication Positive Regulation Of Heart Rate By Epinephrine Oxidation-dependent Protein Catabolic Process
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