IFIT1 and IFIT2

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, cross-linking study, pull down)

		IFIT1	IFIT2
Description		interferon induced protein with tetratricopeptide repeats 1	interferon induced protein with tetratricopeptide repeats 2
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GO Annotations	Cellular Component	Cytoplasm Cytosol Host Cell	Cytoplasm Endoplasmic Reticulum Cytosol
	Molecular Function	RNA Binding Enzyme Inhibitor Activity Protein Binding RNA Sequestering Activity	RNA Binding Protein Binding
	Biological Process	Immune System Process Response To Virus Intracellular Transport Of Viral Protein In Host Cell Positive Regulation Of Viral Genome Replication Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Response To Other Organism Cellular Response To Type I Interferon Cellular Response To Exogenous DsRNA Antiviral Innate Immune Response Negative Regulation Of Viral Translation	Immune System Process Apoptotic Process Apoptotic Mitochondrial Changes Response To Virus Positive Regulation Of Apoptotic Process Innate Immune Response Defense Response To Virus Antiviral Innate Immune Response
Pathways		ISG15 antiviral mechanism Interferon alpha/beta signaling	Interferon alpha/beta signaling
Drugs
Diseases
GWAS
Interacting Genes		5 interacting genes: ANXA1 EIF3E IFIT2 IFIT3 WEE2-AS1	8 interacting genes: IFIT1 IFIT3 LMNA MEOX2 NUTM1 RBPMS2 WWOX WWP2
Entrez ID		3434	3433
HPRD ID		00983	00913
Ensembl ID		ENSG00000185745	ENSG00000119922
Uniprot IDs		P09914	P09913 Q05DN2
PDB IDs		4HOU 5UDI 5UDJ 5UDK 5UDL 5W5H 5W5I 6C6K	4G1T
Enriched GO Terms of Interacting Partners?
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