IFIT2 and IFIT3

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		IFIT2	IFIT3
Description		interferon induced protein with tetratricopeptide repeats 2	interferon induced protein with tetratricopeptide repeats 3
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GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cytosol	Cytoplasm Mitochondrion Cytosol
	Molecular Function	RNA Binding Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Immune System Process Apoptotic Process Apoptotic Mitochondrial Changes Response To Virus Positive Regulation Of Apoptotic Process Innate Immune Response Defense Response To Virus Antiviral Innate Immune Response	Immune System Process Negative Regulation Of Cell Population Proliferation Response To Virus Negative Regulation Of Apoptotic Process Innate Immune Response Defense Response To Virus Antiviral Innate Immune Response
Pathways		Interferon alpha/beta signaling	Interferon alpha/beta signaling
Drugs
Diseases
GWAS			Hormone measurements ( 30576415)
Interacting Genes		8 interacting genes: IFIT1 IFIT3 LMNA MEOX2 NUTM1 RBPMS2 WWOX WWP2	21 interacting genes: A2M ANXA1 APOE CYP2C8 DEUP1 ECSIT FANCA HAUS1 IFIT1 IFIT1B IFIT2 IFIT5 LONP1 LVRN MAST1 PSEN2 RAD23A RNF32 TMEM183A TPM1 TPM3
Entrez ID		3433	3437
HPRD ID		00913	05228
Ensembl ID		ENSG00000119922	ENSG00000119917
Uniprot IDs		P09913 Q05DN2	A0A7P0T7D6 O14879 Q5T765
PDB IDs		4G1T	6C6K
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Viral Translation RNA Sequestering Activity Muscle Thin Filament Tropomyosin Regulation Of Viral Process Response To Stress Negative Regulation Of Viral Process Regulation Of Viral Genome Replication Actin Filament Amyloid Precursor Protein Metabolic Process Defense Response To Virus Regulation Of Viral Life Cycle Innate Immune Response Negative Regulation Of Phospholipid Efflux Negative Regulation Of Postsynaptic Membrane Organization Positive Regulation Of Lipid Transport Across Blood-brain Barrier Negative Regulation Of Lipid Transport Across Blood-brain Barrier Regulation Of Cellular Response To Very-low-density Lipoprotein Particle Stimulus Metal Chelating Activity Intermediate-density Lipoprotein Particle Clearance Response To Virus Positive Regulation Of Viral Genome Replication Positive Regulation Of Heart Rate By Epinephrine Oxidation-dependent Protein Catabolic Process
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