IFIT2

Gene Name		interferon-induced protein with tetratricopeptide repeats 2
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Gene Ontology Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cytosol
	Molecular Function	Protein Binding Poly(A) RNA Binding
	Biological Process	Apoptotic Mitochondrial Changes Response To Virus Cytokine-mediated Signaling Pathway Negative Regulation Of Protein Binding Cellular Response To Interferon-alpha Positive Regulation Of Apoptotic Process Defense Response To Virus Type I Interferon Signaling Pathway
Pathways		Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: IFIT1 IFIT3 NUTM1
Entrez ID		3433
HPRD ID		00913
Ensembl ID		ENSG00000119922
Uniprot IDs		P09913 Q05DN2
PDB IDs		4G1T
Enriched GO Terms of Interacting Partners?		Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Response To Type I Interferon Defense Response To Virus Response To Virus Negative Regulation Of Helicase Activity Cytokine-mediated Signaling Pathway Intracellular Transport Of Viral Protein In Host Cell Cellular Response To Cytokine Stimulus Cellular Response To Exogenous DsRNA Cellular Response To Interferon-alpha Negative Regulation Of Defense Response To Virus By Host Response To Cytokine Response To Other Organism Response To Biotic Stimulus Innate Immune Response Response To Interferon-alpha Positive Regulation Of Viral Genome Replication Negative Regulation Of Defense Response To Virus Intracellular Transport Of Virus Regulation Of Defense Response To Virus By Host Immune Response Cellular Response To DsRNA Defense Response Negative Regulation Of Viral Genome Replication Response To Exogenous DsRNA Negative Regulation Of Protein Binding Regulation Of Viral Genome Replication Response To External Stimulus Positive Regulation Of Viral Process Response To DsRNA Negative Regulation Of Viral Process Cellular Response To Organic Substance Regulation Of Defense Response To Virus Negative Regulation Of Binding Immune System Process Interaction With Host Response To Organic Substance Regulation Of Protein Binding Regulation Of Viral Process Viral Life Cycle Cell Surface Receptor Signaling Pathway Response To Stress Regulation Of Binding Negative Regulation Of Immune System Process
Tagcloud ?		adenovirus apobec3a ddx58 exact expand hiv ifi27 ifi44l ifit1 ifit3 innate irf7 isg15 isg20 isgs mdms microarray monocyte mx1 mx2 reservoirs rig rsad2 select stat1 tnfsf10 trail viperin vpr