IFIT2 and IFIT1

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, cross-linking study, pull down)

		IFIT2	IFIT1
Description		interferon induced protein with tetratricopeptide repeats 2	interferon induced protein with tetratricopeptide repeats 1
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GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cytosol	Cytoplasm Cytosol Host Cell
	Molecular Function	RNA Binding Protein Binding	RNA Binding Enzyme Inhibitor Activity Protein Binding RNA Sequestering Activity
	Biological Process	Immune System Process Apoptotic Process Apoptotic Mitochondrial Changes Response To Virus Positive Regulation Of Apoptotic Process Innate Immune Response Defense Response To Virus Antiviral Innate Immune Response	Immune System Process Response To Virus Intracellular Transport Of Viral Protein In Host Cell Positive Regulation Of Viral Genome Replication Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Response To Other Organism Cellular Response To Type I Interferon Cellular Response To Exogenous DsRNA Antiviral Innate Immune Response Negative Regulation Of Viral Translation
Pathways		Interferon alpha/beta signaling	ISG15 antiviral mechanism Interferon alpha/beta signaling
Drugs
Diseases
GWAS
Interacting Genes		8 interacting genes: IFIT1 IFIT3 LMNA MEOX2 NUTM1 RBPMS2 WWOX WWP2	5 interacting genes: ANXA1 EIF3E IFIT2 IFIT3 WEE2-AS1
Entrez ID		3433	3434
HPRD ID		00913	00983
Ensembl ID		ENSG00000119922	ENSG00000185745
Uniprot IDs		P09913 Q05DN2	P09914
PDB IDs		4G1T	4HOU 5UDI 5UDJ 5UDK 5UDL 5W5H 5W5I 6C6K
Enriched GO Terms of Interacting Partners?
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