STAC2 and ATXN1L

Number of citations of the paper that reports this interaction (PubMedID 16713569)
0

Data Source:
BioGRID (two hybrid)

		STAC2	ATXN1L
Description		SH3 and cysteine rich domain 2	ataxin 1 like
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Sarcolemma	Nucleus Nucleoplasm Nucleolus Dendrite Cell Projection
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	DNA Binding Chromatin Binding RNA Binding Protein Binding POZ Domain Binding
	Biological Process	Skeletal Muscle Contraction Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Localization To Plasma Membrane	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Transcription By RNA Polymerase II Brain Development Learning Memory Extracellular Matrix Organization Social Behavior Lung Alveolus Development Positive Regulation Of Hematopoietic Stem Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Asthma ( 31619474) Refractive error ( 32231278) Ulcerative colitis ( 20228799)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Response to anti-TNF therapy in rheumatoid arthritis ( 26776603) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		6 interacting genes: ATXN1 ATXN1L BRCA1 LMNA LNX1 PRKAA2	83 interacting genes: ACO2 ACOT7 ADORA1 AFAP1L2 AGXT ALG13 ANKHD1 AP1G2 AP2M1 APBB1 ARID5A ATXN1 C1orf94 CAMSAP2 CBFA2T2 CDSN CHD6 COIL CTBP1 DAB2 DAZAP2 EPB41L2 EPB41L3 FADS2 FAM168A FOXH1 FUS GAS7 GMEB2 GORASP2 GPATCH8 HGS HIVEP1 HLX HSFX1 KRTAP11-1 KRTAP13-1 KRTAP19-7 KRTAP21-2 KRTAP8-1 LARP4B MACROH2A1 MATN2 MBD1 MBD6 MEIS3 MEOX2 METTL17 METTL27 MYOZ3 NBR1 NCOR1 NCOR2 NIT1 NUTM2F PHPT1 PICALM PICK1 PRRC2B RAD54L2 RBFOX1 RBFOX2 RRAGC SCAF11 SHISA2 SMARCC2 SPMIP9 SREBF1 ST6GALNAC6 STAC2 SUGP2 TBX2 THY1 TMEM25 TMEM8B TRIP11 UNKL USP54 YPEL3 YY1AP1 ZBTB32 ZC3H7B ZSWIM8
Entrez ID		342667	342371
HPRD ID		18113	19555
Ensembl ID		ENSG00000141750	ENSG00000224470
Uniprot IDs		D0IN09 Q6ZMT1	P0C7T5
PDB IDs		6B26 6B27 6B28
Enriched GO Terms of Interacting Partners?		POZ Domain Binding Protein K6-linked Ubiquitination Regulation Of Release Of Cytochrome C From Mitochondria Social Behavior Lung Alveolus Development Histone H2AK127 Ubiquitin Ligase Activity Negative Regulation Of Macromolecule Biosynthetic Process Histone H2AK129 Ubiquitin Ligase Activity Negative Regulation Of Biosynthetic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway BRCA1-BARD1 Complex DNA Double-strand Break Attachment To Nuclear Envelope Structural Constituent Of Nuclear Lamina Chromatin Binding [hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity Histone H2BS36 Kinase Activity Regulation Of Mitochondrion Organization Fatty Acid Biosynthetic Process Memory Negative Regulation Of Signal Transduction BRCA1-B Complex Regulation Of Extrinsic Apoptotic Signaling Pathway Cellular Response To Indole-3-methanol Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Metabolic Process Chromatin Remodeling Heterochromatin Formation Negative Regulation Of Cell Communication Negative Regulation Of Macromolecule Metabolic Process Protein Modification By Small Protein Conjugation Protein Ubiquitination Negative Regulation Of Signaling Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Lamin Filament Nuclear Matrix Nuclear Pore Localization Protein Localization To Lipid Droplet Learning Nuclear Ubiquitin Ligase Complex BRCA1-C Complex Response To Indole-3-methanol Negative Regulation Of Hepatocyte Apoptotic Process Negative Regulation Of Tubulin Deacetylation AMP-activated Protein Kinase Activity Negative Regulation Of Centriole Replication BRCA1-A Complex Post-translational Protein Modification Negative Regulation Of Apoptotic Signaling Pathway Gamma-tubulin Ring Complex Negative Regulation Of Programmed Cell Death	Negative Regulation Of Androgen Receptor Signaling Pathway Low-density Lipoprotein Particle Receptor Binding Regulation Of Androgen Receptor Signaling Pathway Axolemma Chromatin Binding Negative Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Clathrin Adaptor Activity Regulation Of Protein Localization To Cell Periphery Transcription Corepressor Activity Clathrin Coat Assembly Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Nuclear Body Positive Regulation Of Response To Oxidative Stress Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Extrinsic Component Of Presynaptic Endocytic Zone Membrane Double-stranded Methylated DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Negative Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of 3'-UTR-mediated MRNA Stabilization Regulation Of Protein Localization Clathrin-coated Pit Clathrin-dependent Endocytosis Sequence-specific DNA Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Protein Localization Chromatin Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process
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