RSPO2 and KRTAP10-1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RSPO2	KRTAP10-1
Gene Name		R-spondin 2	keratin associated protein 10-1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Surface	Keratin Filament
	Molecular Function	G-protein Coupled Receptor Binding Receptor Binding Heparin Binding
	Biological Process	Osteoblast Differentiation Wnt Signaling Pathway Bone Mineralization Embryonic Forelimb Morphogenesis Embryonic Hindlimb Morphogenesis Lung Growth Epithelial Tube Branching Involved In Lung Morphogenesis Trachea Cartilage Morphogenesis Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways		misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation regulation of FZD by ubiquitination XAV939 inhibits tankyrase, stabilizing AXIN Signaling by Wnt Signaling by WNT in cancer
Drugs
Diseases
GWAS		Dupuytren's disease ( 21732829)
Protein-Protein Interactions		8 interactors: JMJD6 KRTAP10-1 KRTAP10-4 KRTAP10-7 KRTAP10-9 LGR4 PLEKHF2 SUV39H1	73 interactors: ADAMTSL4 AEN AVPI1 BAHD1 BCL6B C19orf66 CARD9 CATSPER1 CBX2 CHIC2 CHRD CREB5 CXCL16 DAAM2 DHX57 DKK1 DOCK2 ECE1 FAM76B GLRX3 HOXA1 HPCAL1 HSD3B7 KRTAP10-3 KRTAP12-1 KRTAP2-4 KRTAP26-1 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE3E MAPKBP1 MEOX2 MOBP NOTCH2NL NPDC1 NR4A1 OTX1 PID1 PIN1 POM121L8P PRM2 PRPF31 PVRL2 RSPO2 SLC23A1 SLC6A20 SPATA8 SPRY1 SPRY2 TULP3 ZBTB24 ZNF101 ZNF124 ZNF264 ZNF286A ZNF329 ZNF417 ZNF433 ZNF439 ZNF440 ZNF559 ZNF572 ZNF581 ZNF587 ZNF785 ZSCAN12 ZSCAN26
Entrez ID		340419	386677
HPRD ID		17536	11184
Ensembl ID		ENSG00000147655	ENSG00000215455
Uniprot IDs		B3KVP3 Q6UXX9	P60331
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone H3-R2 Demethylation Histone H4-R3 Demethylation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Canonical Wnt Signaling Pathway Involved In Metanephric Kidney Development Peptidyl-lysine Modification Rhythmic Process Kidney Development Histone H3-K9 Dimethylation Renal System Development Recognition Of Apoptotic Cell Metanephric Nephron Tubule Morphogenesis Urogenital System Development Histone Modification Histone H3-K9 Trimethylation Peptidyl-lysine Dimethylation Cell Differentiation Involved In Metanephros Development Metanephric Tubule Morphogenesis Chromatin Silencing At RDNA Phagocytosis, Recognition Metanephric Glomerulus Development Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Metanephric Nephron Tubule Development Negative Regulation Of Circadian Rhythm Regulation Of Branching Involved In Ureteric Bud Morphogenesis Chromatin Modification Histone H3-K9 Methylation Metanephric Nephron Morphogenesis Negative Regulation Of Toll-like Receptor Signaling Pathway Peptidyl-lysine Trimethylation Protein Hydroxylation Male Genitalia Development Metanephric Epithelium Development Macrophage Activation Tube Development Chromatin Organization Apoptotic Cell Clearance Metanephros Morphogenesis Chromatin Silencing Histone Demethylation Histone H3-K9 Modification Negative Regulation Of Cytokine Secretion Positive Regulation Of Kidney Development Protein Demethylation Cell Differentiation Involved In Kidney Development Metanephric Nephron Development Regulation Of Toll-like Receptor Signaling Pathway Erythrocyte Development Bone Mineralization Peptidyl-amino Acid Modification Sprouting Angiogenesis	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Regulation Of Transcription, DNA-templated Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Cellular Process Biosynthetic Process Lung Growth Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning Regulation Of Neurotrophin TRK Receptor Signaling Pathway Limb Development Embryonic Morphogenesis Pattern Specification Process Developmental Process Embryonic Neurocranium Morphogenesis Epithelial Tube Branching Involved In Lung Morphogenesis Epithelium Development Cellular Process Bud Elongation Involved In Lung Branching Negative Regulation Of ERK1 And ERK2 Cascade Multicellular Organismal Development Respiratory Tube Development Anterior/posterior Pattern Specification Organ Development Lung Morphogenesis Respiratory System Development Embryonic Limb Morphogenesis Tissue Development Cell Differentiation Negative Regulation Of Ras GTPase Activity Limb Morphogenesis Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Tube Development Embryo Development Branch Elongation Of An Epithelium Inner Ear Morphogenesis
Tagcloud ?		293t aquaporin bring cdnas conditioned conservation dependently ectodomain ed endogenously gonadal gonads intraperitoneal leucine lgr4 lh named naturally newborn norrin rodent splice spondin spondins steroidogenic superovulated testicular tune wnt
Tagcloud (Difference) ?		293t aquaporin bring cdnas conditioned conservation dependently ectodomain ed endogenously gonadal gonads intraperitoneal leucine lgr4 lh named naturally newborn norrin rodent splice spondin spondins steroidogenic superovulated testicular tune wnt
Tagcloud (Intersection) ?