KRTAP10-1 and DAAM2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		KRTAP10-1	DAAM2
Description		keratin associated protein 10-1	dishevelled associated activator of morphogenesis 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Extracellular Exosome
	Molecular Function		Actin Binding Protein Binding Small GTPase Binding
	Biological Process		Determination Of Left/right Symmetry Wnt Signaling Pathway Dorsal Spinal Cord Development Actin Cytoskeleton Organization Positive Regulation Of Cell Migration Regulation Of Actin Filament Polymerization Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Oligodendrocyte Differentiation Regulation Of Filopodium Assembly Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Canonical Wnt Signaling Pathway Podocyte Cell Migration Regulation Of Non-canonical Wnt Signaling Pathway
Pathways		Keratinization
Drugs
Diseases
GWAS			Appendicular lean mass ( 33097823) Brain morphology (MOSTest) ( 32665545) Heel bone mineral density ( 30598549) Height ( 31562340) Hypospadias ( 25108383) Intraocular pressure ( 29785010) Pulmonary function ( 20010834) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		152 interacting genes: ADAMTSL4 AEN AMMECR1 ATP23 AVPI1 BAHD1 BCL6B C17orf50 C22orf39 CAMK1G CARD9 CATSPER1 CBX2 CHIC2 CHRD CLPP CRCT1 CREB5 CTSZ CXCL16 CYSRT1 DAAM2 DEFB112 DHX57 DKK1 DOCK2 ECE1 FAM76B FBXO34 FCHO1 FUCA2 GLRX3 HOXA1 HOXA9 HPCAL1 HSD3B7 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP13-3 KRTAP2-3 KRTAP2-4 KRTAP21-2 KRTAP26-1 KRTAP3-2 KRTAP3-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-1 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LINGO1 MAPKBP1 MEOX2 MOBP MRPL12 NBPF19 NECTIN2 NKD1 NLK NOTCH2NLA NPDC1 NR1D2 NR4A1 NR4A3 NUFIP2 OTX1 PID1 PIN1 PLLP POM121L8P POU4F2 PPARA PRKAG1 PRM2 PRPF31 RNF8 RSPO2 SH3GLB2 SHFL SLC23A1 SLC6A20 SMCP SPATA24 SPATA3 SPATA8 SPRY1 SPRY2 TNP2 TRIM42 TSPAN4 TULP3 WT1 ZBTB24 ZNF101 ZNF124 ZNF138 ZNF264 ZNF286A ZNF329 ZNF417 ZNF433 ZNF438 ZNF439 ZNF440 ZNF559 ZNF572 ZNF581 ZNF587 ZNF625 ZNF664 ZNF768 ZNF785 ZSCAN12 ZSCAN26	16 interacting genes: EHHADH EXOSC5 HGS KCNIP1 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 MDFI RBMY1A1 RBMY1F REL TH TIAM1 TTC3
Entrez ID		386677	23500
HPRD ID		11184	09434
Ensembl ID		ENSG00000215455	ENSG00000146122
Uniprot IDs		P60331	A0A0J9YYF7 Q86T65
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Protein Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Hair Cycle RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Zinc Ion Binding DNA Binding Lung Growth Identical Protein Binding DNA-binding Transcription Factor Activity Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding	Keratin Filament Intermediate Filament Cytosol Positive Regulation Of MRNA Splicing, Via Spliceosome
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