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RSPO2 and KRTAP10-9
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
RSPO2
KRTAP10-9
Gene Name
R-spondin 2
keratin associated protein 10-9
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cell Surface
Keratin Filament
Molecular Function
G-protein Coupled Receptor Binding
Receptor Binding
Heparin Binding
Biological Process
Osteoblast Differentiation
Wnt Signaling Pathway
Bone Mineralization
Embryonic Forelimb Morphogenesis
Embryonic Hindlimb Morphogenesis
Lung Growth
Epithelial Tube Branching Involved In Lung Morphogenesis
Trachea Cartilage Morphogenesis
Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
TCF dependent signaling in response to WNT
RNF mutants show enhanced WNT signaling and proliferation
regulation of FZD by ubiquitination
XAV939 inhibits tankyrase, stabilizing AXIN
Signaling by Wnt
Signaling by WNT in cancer
Drugs
Diseases
GWAS
Dupuytren's disease (
21732829
)
Protein-Protein Interactions
8 interactors:
JMJD6
KRTAP10-1
KRTAP10-4
KRTAP10-7
KRTAP10-9
LGR4
PLEKHF2
SUV39H1
163 interactors:
ADAMTSL4
AES
ALDH3B1
ALPI
ARFGAP1
ATXN7L1
AVPI1
BCL6B
C10orf62
C11orf87
C16orf59
C19orf57
C19orf66
C5orf60
C9orf9
CARKD
CATIP
CATSPER1
CBX2
CCDC26
CD300LG
CDKL3
CHIC2
CHRD
CHRNG
CKS1B
CLK4
CNNM3
CRCT1
CREB5
CST9L
CXCL16
DHX57
DMRT3
DOCK2
EIF4E2
FAM124B
FAM161A
FAM74A4
FAM76B
FARS2
GABARAPL1
GABARAPL2
GATA2
GLIDR
GLP1R
GLRX3
GNE
GPATCH2L
GSTP1
HBG1
HBZ
HCK
HOXA1
HOXB9
HPCAL1
HSD3B7
IGSF8
INPP5D
IQUB
ITGB5
KAT5
KIF9
KLHL38
KRT20
KRT83
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP12-1
KRTAP26-1
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-4
LCE1B
LCE2A
LCE2D
LCE3C
LCE3E
LCE4A
LUZP4
MAB21L3
MAPKBP1
MED30
MEOX2
MOBP
MT1DP
MXI1
NOTCH2NL
NPBWR2
NPDC1
NPPB
NR1D2
NUFIP2
OTX1
PGAP2
PGLS
PIN1
PLSCR1
PRKAB2
PRPF31
PTGER3
PVR
PVRL3
RAB7A
RHNO1
RSPO2
SCARB1
SCNM1
SLC23A1
SLC6A20
SMARCE1
SMCP
SPATA3
SPATA8
SPG7
SPRY1
SPRY2
STK16
TBC1D16
TBC1D23
TGOLN2
THAP10
TNFRSF6B
TNP2
TRIM41
TRIM42
TXNDC5
TYMSOS
TYRO3
UTP23
WNT11
WT1-AS
XCL2
ZBTB24
ZBTB38
ZBTB9
ZFYVE26
ZNF124
ZNF155
ZNF20
ZNF264
ZNF317
ZNF417
ZNF439
ZNF440
ZNF473
ZNF564
ZNF572
ZNF578
ZNF581
ZNF587
ZNF625
ZNF697
ZNF699
ZNF792
ZNF844
ZSCAN21
ZSCAN26
Entrez ID
340419
386676
HPRD ID
17536
11195
Ensembl ID
ENSG00000147655
ENSG00000221837
Uniprot IDs
B3KVP3
Q6UXX9
P60411
PDB IDs
Enriched GO Terms of Interacting Partners
?
Histone H3-R2 Demethylation
Histone H4-R3 Demethylation
Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine
Canonical Wnt Signaling Pathway Involved In Metanephric Kidney Development
Peptidyl-lysine Modification
Rhythmic Process
Kidney Development
Histone H3-K9 Dimethylation
Renal System Development
Recognition Of Apoptotic Cell
Metanephric Nephron Tubule Morphogenesis
Urogenital System Development
Histone Modification
Histone H3-K9 Trimethylation
Peptidyl-lysine Dimethylation
Cell Differentiation Involved In Metanephros Development
Metanephric Tubule Morphogenesis
Chromatin Silencing At RDNA
Phagocytosis, Recognition
Metanephric Glomerulus Development
Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis
Metanephric Nephron Tubule Development
Negative Regulation Of Circadian Rhythm
Regulation Of Branching Involved In Ureteric Bud Morphogenesis
Chromatin Modification
Histone H3-K9 Methylation
Metanephric Nephron Morphogenesis
Negative Regulation Of Toll-like Receptor Signaling Pathway
Peptidyl-lysine Trimethylation
Protein Hydroxylation
Male Genitalia Development
Metanephric Epithelium Development
Macrophage Activation
Tube Development
Chromatin Organization
Apoptotic Cell Clearance
Metanephros Morphogenesis
Chromatin Silencing
Histone Demethylation
Histone H3-K9 Modification
Negative Regulation Of Cytokine Secretion
Positive Regulation Of Kidney Development
Protein Demethylation
Cell Differentiation Involved In Kidney Development
Metanephric Nephron Development
Regulation Of Toll-like Receptor Signaling Pathway
Erythrocyte Development
Bone Mineralization
Peptidyl-amino Acid Modification
Sprouting Angiogenesis
Transcription, DNA-templated
RNA Biosynthetic Process
RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Biosynthetic Process
Keratinization
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of RNA Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Metabolic Process
Nitrogen Compound Metabolic Process
Regulation Of Cellular Process
Cellular Process
Keratinocyte Differentiation
Cellular Metabolic Process
Epidermis Development
Epidermal Cell Differentiation
Lung Growth
Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Negative Regulation Of ERK1 And ERK2 Cascade
Regulation Of Phagocytosis
Regulation Of Transcription From RNA Polymerase II Promoter
Developmental Process
Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Podosome Assembly
Apoptotic Cell Clearance
Penetration Of Zona Pellucida
Organelle Disassembly
Tissue Development
Skin Development
Epithelium Development
Multicellular Organismal Development
Bud Elongation Involved In Lung Branching
Cellular Response To Lipid
Epithelial Tube Branching Involved In Lung Morphogenesis
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Inner Ear Morphogenesis
Fertilization
Negative Regulation Of ERBB Signaling Pathway
Phagocytosis
Anatomical Structure Development
Tagcloud
?
293t
aquaporin
bring
cdnas
conditioned
conservation
dependently
ectodomain
ed
endogenously
gonadal
gonads
intraperitoneal
leucine
lgr4
lh
named
naturally
newborn
norrin
rodent
splice
spondin
spondins
steroidogenic
superovulated
testicular
tune
wnt
Tagcloud (Difference)
?
293t
aquaporin
bring
cdnas
conditioned
conservation
dependently
ectodomain
ed
endogenously
gonadal
gonads
intraperitoneal
leucine
lgr4
lh
named
naturally
newborn
norrin
rodent
splice
spondin
spondins
steroidogenic
superovulated
testicular
tune
wnt
Tagcloud (Intersection)
?