KRTAP10-1 and CTSZ

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP10-1	CTSZ
Description		keratin associated protein 10-1	cathepsin Z
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Extracellular Region Extracellular Space Lysosome Endoplasmic Reticulum Endoplasmic Reticulum Lumen Plasma Membrane Cell Cortex Cell Surface COPII-coated ER To Golgi Transport Vesicle Growth Cone Extracellular Matrix Cytoplasmic Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Specific Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function		Carboxypeptidase Activity Cysteine-type Endopeptidase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity Cysteine-type Carboxypeptidase Activity
	Biological Process		Angiotensin Maturation Proteolysis Negative Regulation Of Plasminogen Activation Proteolysis Involved In Protein Catabolic Process Epithelial Tube Branching Involved In Lung Morphogenesis
Pathways		Keratinization	Metabolism of Angiotensinogen to Angiotensins COPII-mediated vesicle transport Lysosome Vesicle Biogenesis Cargo concentration in the ER Neutrophil degranulation
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Heel bone mineral density x serum urate levels interaction ( 34046847) Hematocrit ( 32888494) Inflammatory bowel disease ( 23128233) Lymphocyte count ( 32888494) Mean platelet volume ( 22139419 24026423 27863252 32888494) Platelet count ( 32888494) Platelet distribution width ( 27863252 32888494)
Interacting Genes		152 interacting genes: ADAMTSL4 AEN AMMECR1 ATP23 AVPI1 BAHD1 BCL6B C17orf50 C22orf39 CAMK1G CARD9 CATSPER1 CBX2 CHIC2 CHRD CLPP CRCT1 CREB5 CTSZ CXCL16 CYSRT1 DAAM2 DEFB112 DHX57 DKK1 DOCK2 ECE1 FAM76B FBXO34 FCHO1 FUCA2 GLRX3 HOXA1 HOXA9 HPCAL1 HSD3B7 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP13-3 KRTAP2-3 KRTAP2-4 KRTAP21-2 KRTAP26-1 KRTAP3-2 KRTAP3-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-1 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LINGO1 MAPKBP1 MEOX2 MOBP MRPL12 NBPF19 NECTIN2 NKD1 NLK NOTCH2NLA NPDC1 NR1D2 NR4A1 NR4A3 NUFIP2 OTX1 PID1 PIN1 PLLP POM121L8P POU4F2 PPARA PRKAG1 PRM2 PRPF31 RNF8 RSPO2 SH3GLB2 SHFL SLC23A1 SLC6A20 SMCP SPATA24 SPATA3 SPATA8 SPRY1 SPRY2 TNP2 TRIM42 TSPAN4 TULP3 WT1 ZBTB24 ZNF101 ZNF124 ZNF138 ZNF264 ZNF286A ZNF329 ZNF417 ZNF433 ZNF438 ZNF439 ZNF440 ZNF559 ZNF572 ZNF581 ZNF587 ZNF625 ZNF664 ZNF768 ZNF785 ZSCAN12 ZSCAN26	21 interacting genes: BACH2 BANP CYSRT1 FHL5 HSF2BP KRT35 KRT40 KRTAP1-1 KRTAP10-1 KRTAP10-10 KRTAP2-3 KRTAP2-4 KRTAP3-3 KRTAP5-9 KRTAP6-3 MID2 MTUS2 NBPF19 NOTCH2NLA PLSCR1 TNS2
Entrez ID		386677	1522
HPRD ID		11184	04410
Ensembl ID		ENSG00000215455	ENSG00000101160
Uniprot IDs		P60331	Q9UBR2
PDB IDs			1DEU 1EF7
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Protein Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Hair Cycle RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Zinc Ion Binding DNA Binding Lung Growth Identical Protein Binding DNA-binding Transcription Factor Activity Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding	Intermediate Filament Keratin Filament
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