TRIML1 and RBCK1

Number of citations of the paper that reports this interaction (PMID 22493164)
2

Data Source:
BioGRID (two hybrid)

		TRIML1	RBCK1
Gene Name		tripartite motif family-like 1	RanBP-type and C3HC4-type zinc finger containing 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		LUBAC Complex
	Molecular Function	Zinc Ion Binding Ligase Activity	Sequence-specific DNA Binding Transcription Factor Activity Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Ubiquitin Binding
	Biological Process	Multicellular Organismal Development Protein Ubiquitination	Protein Polyubiquitination Viral Process Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of NF-kappaB Import Into Nucleus Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process T Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Necroptotic Process Protein Linear Polyubiquitination Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: APP MNAT1 RBCK1 USP5	46 interactors: APP ARNT2 BACH1 CREBBP IKBKG IREB2 MKRN2 NAA10 NDUFAF3 NEDD4 NR1I2 OTUB2 OTUD6A PAN2 PARK2 PCGF2 PRKCA PSMD4 RNF181 RNF31 SOCS6 SYCE1 TNFAIP3 TRAF1 TRIM21 TRIM25 TRIM65 TRIML1 TSSK3 UBE2D3 UBE2D4 UBE2G1 UBE2K UBE2L3 UBE2L6 UBE2N UBE2S UBE2U UCHL5 UHRF2 USP15 USP2 USP21 USP32 USP49 USP7
Entrez ID		339976	10616
HPRD ID		08774	16643
Ensembl ID		ENSG00000184108	ENSG00000125826
Uniprot IDs		Q8N9V2	A6PVK0 Q9BYM8
PDB IDs			2CRC 2LGY 4DBG
Enriched GO Terms of Interacting Partners?		Cellular Macromolecule Catabolic Process Synaptic Growth At Neuromuscular Junction Cellular Protein Modification Process Collateral Sprouting In Absence Of Injury Protein Linear Polyubiquitination Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Proteolysis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Cellular Protein Metabolic Process Neuron Remodeling Catabolic Process MRNA Processing Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Necroptotic Process Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Necrotic Cell Death Modification-dependent Protein Catabolic Process Adult Heart Development Protein K48-linked Deubiquitination Regulation Of Necroptotic Process Regulation Of Protein Metabolic Process MRNA Metabolic Process Protein Metabolic Process Nucleotide-excision Repair, DNA Damage Removal Cellular Copper Ion Homeostasis Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process RNA Processing Positive Regulation Of NF-kappaB Import Into Nucleus Copper Ion Homeostasis Suckling Behavior Regulation Of Necrotic Cell Death Protein Catabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Regulation Of Proteolysis Transcription Initiation From RNA Polymerase I Promoter Positive Regulation Of Cellular Metabolic Process Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity 7-methylguanosine MRNA Capping Transcription From RNA Polymerase I Promoter Regulation Of Protein Kinase Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis	Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Protein Modification Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Catabolic Process Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process Proteolysis Proteasomal Protein Catabolic Process Protein Metabolic Process Protein Deubiquitination Protein Modification By Small Protein Removal Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Catabolic Process Cellular Metabolic Process Regulation Of Protein Catabolic Process Regulation Of Type I Interferon Production Protein K63-linked Ubiquitination Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Protein K48-linked Ubiquitination Regulation Of Proteasomal Protein Catabolic Process Response To Stress Regulation Of Proteolysis Histone Modification Histone Deubiquitination Cellular Response To Stress Protein K29-linked Ubiquitination Protein K27-linked Ubiquitination Protein K11-linked Ubiquitination Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Innate Immune Response Chromosome Organization Protein K6-linked Ubiquitination Protein K11-linked Deubiquitination Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Protein Monoubiquitination Chromatin Modification Protein Autoubiquitination Negative Regulation Of Type I Interferon Production Cellular Process Regulation Of Transcription, DNA-templated
Tagcloud ?			1beta ali allocated attenuates autologous c3hc4 dependently dismutase histology intravenously malondialdehyde mda oalt occluded orthotopic oxidant pathologic peroxiredoxin portal prx ranbp restoring sham sod started u1 uh ul ulinastatin
Tagcloud (Difference) ?			1beta ali allocated attenuates autologous c3hc4 dependently dismutase histology intravenously malondialdehyde mda oalt occluded orthotopic oxidant pathologic peroxiredoxin portal prx ranbp restoring sham sod started u1 uh ul ulinastatin
Tagcloud (Intersection) ?