ICAM2 and ATP13A2

Number of citations of the paper that reports this interaction (PMID 22645275)
9

Data Source:
BioGRID (two hybrid)

		ICAM2	ATP13A2
Gene Name		intercellular adhesion molecule 2	ATPase type 13A2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Uropod Plasma Membrane Integral Component Of Plasma Membrane Membrane Extracellular Vesicular Exosome	Lysosome Lysosomal Membrane Integral Component Of Membrane
	Molecular Function	Integrin Binding	Protein Binding ATP Binding ATPase Activity Metal Ion Binding
	Biological Process	Cell Adhesion Single Organismal Cell-cell Adhesion Extracellular Matrix Organization Regulation Of Immune Response	Cation Transport Metabolic Process Cellular Response To Manganese Ion
Pathways		Integrin cell surface interactions Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs
Diseases
GWAS			Height ( 20189936)
Protein-Protein Interactions		7 interactors: ATP13A2 CD209 EZR ITGAM ITGB2 MSN RDX	36 interactors: ACKR3 ATP5G2 CCKBR CMTM6 COL1A1 CXCR4 CYGB DCAF7 EMC7 F2R FAM111B FAM192A FAM8A1 FKBP8 FUNDC2 GPR21 HIPK1 ICAM2 LMAN2 LRP6 MEX3B MYCBP2 NPY1R NRXN1 OCA2 OSTC PCDHB10 PCMTD2 PDIA6 SEC61B SPCS2 TSPAN14 UBE2J2 VAMP2 WDR5B WDR83OS
Entrez ID		3384	23400
HPRD ID		00888	13677
Ensembl ID		ENSG00000108622	ENSG00000159363
Uniprot IDs		P13598 Q6FHE2	Q9NQ11
PDB IDs		1ZXQ
Enriched GO Terms of Interacting Partners?		Leukocyte Cell-cell Adhesion Establishment Of Endothelial Barrier Single Organismal Cell-cell Adhesion Endothelial Cell Development Membrane To Membrane Docking Endothelial Cell Differentiation Endothelium Development Leukocyte Migration Involved In Inflammatory Response Microvillus Assembly Microvillus Organization Cell Adhesion Cellular Extravasation Activated T Cell Proliferation Epithelial Cell Development Leukocyte Migration Tissue Development Neutrophil Chemotaxis Neutrophil Migration Granulocyte Chemotaxis T Cell Proliferation Locomotion Toll-like Receptor 4 Signaling Pathway Regulation Of Immune System Process Membrane Docking Leukocyte Chemotaxis Epithelial Cell Differentiation Toll-like Receptor Signaling Pathway Lymphocyte Proliferation Mononuclear Cell Proliferation Movement Of Cell Or Subcellular Component Integrin-mediated Signaling Pathway Chemotaxis Leukocyte Proliferation Microglia Development Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Peptide Antigen Transport Cell Chemotaxis Regulation Of Cell Shape Cell Development Cell Differentiation Positive Regulation Of Innate Immune Response Innate Immune Response Cell Migration Cellular Response To Manganese Ion Ectodermal Cell Differentiation Cell Motility Immune System Process Virion Attachment To Host Cell	Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Homeostasis Protein Localization To Membrane Embryonic Retina Morphogenesis In Camera-type Eye Establishment Of Protein Localization To Membrane Regulation Of Signaling Establishment Of Protein Localization Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Cellular Localization Membrane Organization Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cardiovascular System Development Synaptic Transmission Motor Neuron Axon Guidance Cell-cell Signaling Locomotion Positive Regulation Of Signal Transduction Chemotaxis Face Morphogenesis Embryonic Camera-type Eye Morphogenesis ER-associated Ubiquitin-dependent Protein Catabolic Process Head Morphogenesis Positive Regulation Of Wnt Signaling Pathway Involved In Dorsal/ventral Axis Specification Canonical Wnt Signaling Pathway Involved In Cardiac Neural Crest Cell Differentiation Involved In Heart Development Negative Regulation Of Planar Cell Polarity Pathway Involved In Neural Tube Closure Negative Regulation Of Planar Cell Polarity Pathway Involved In Outflow Tract Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Pericardium Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Cardiac Right Atrium Morphogenesis Negative Regulation Of Renin Secretion Into Blood Stream Negative Regulation Of Planar Cell Polarity Pathway Involved In Cardiac Muscle Tissue Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Ventricular Septum Morphogenesis Cellular Response To Fluoride Protein Complex Assembly Involved In Synapse Maturation Gamma-aminobutyric Acid Receptor Clustering Tyrosine Transport Synapse Organization Protein Localization To Nucleus Embryonic Eye Morphogenesis Cellular Protein Localization Regulation Of Protein Secretion Cellular Metal Ion Homeostasis Response To External Stimulus Cellular Homeostasis Cerebellum Morphogenesis Anatomical Structure Formation Involved In Morphogenesis Face Development Regulation Of Signal Transduction Cellular Protein Metabolic Process Regulation Of Insulin Secretion
Tagcloud ?		aap aat affymetrix alopecia areata ccl5 cd27 cx3cl1 cxcl10 cxcr5 degs distinctly ereg etiopathogenesis favoring fgf18 fgf5 foxc2 hair hu95a icam3 ighg3 ighm il7r lck lesional separating sfn v2	ataxin atxn3 b12 cag cgg chediak coexist cytopathies fmr1 fragile gaucher gba glucocerebrosidase hereditary higashi idiopathic joseph kufor levodopa lyst machado park2 parkin parkinsonism pn polg1 premutation rakeb tremor
Tagcloud (Difference) ?		aap aat affymetrix alopecia areata ccl5 cd27 cx3cl1 cxcl10 cxcr5 degs distinctly ereg etiopathogenesis favoring fgf18 fgf5 foxc2 hair hu95a icam3 ighg3 ighm il7r lck lesional separating sfn v2	ataxin atxn3 b12 cag cgg chediak coexist cytopathies fmr1 fragile gaucher gba glucocerebrosidase hereditary higashi idiopathic joseph kufor levodopa lyst machado park2 parkin parkinsonism pn polg1 premutation rakeb tremor
Tagcloud (Intersection) ?