HTR7 and GPRASP2

Number of citations of the paper that reports this interaction (PMID 15086532)
18

Data Source:
HPRD (in vitro)

		HTR7	GPRASP2
Gene Name		5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled	G protein-coupled receptor associated sorting protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Cytoplasm
	Molecular Function	Serotonin Receptor Activity	Beta-amyloid Binding
	Biological Process	Smooth Muscle Contraction G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Serotonin Receptor Signaling Pathway Synaptic Transmission Circadian Rhythm Blood Circulation Vasoconstriction
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events Class A/1 (Rhodopsin-like receptors) Amine ligand-binding receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding Serotonin receptors
Drugs		Eletriptan Ziprasidone Methysergide Cabergoline Olanzapine Clozapine Epinastine Bromocriptine Quetiapine Aripiprazole Iloperidone Asenapine Amisulpride Lurasidone
Diseases
GWAS
Protein-Protein Interactions		2 interactors: GPRASP1 GPRASP2	25 interactors: ADRB1 ARHGEF6 BARD1 BZRAP1 C6orf165 CALCR CBX8 CHRM1 CHRM2 DISC1 FRAT1 HAP1 HRH2 HTR7 HTT KIAA1377 LOC149950 LRIF1 MYOT PTN RPS6KA5 STMN2 TCF25 TXN TXN2
Entrez ID		3363	114928
HPRD ID		01639	06612
Ensembl ID		ENSG00000148680	ENSG00000158301
Uniprot IDs		P34969	B3KW05 Q96D09
PDB IDs
Enriched GO Terms of Interacting Partners?		G-protein Coupled Receptor Catabolic Process Receptor Catabolic Process Endosome To Lysosome Transport Lysosomal Transport Vacuolar Transport Receptor Metabolic Process Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Endosomal Transport	G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Cell Surface Receptor Signaling Pathway Cell-cell Signaling Homeostatic Process Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Phospholipase C-activating G-protein Coupled Acetylcholine Receptor Signaling Pathway Positive Regulation Of Cation Channel Activity Cell Communication Cellular Response To Stimulus Cognition Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Synaptic Transmission Positive Regulation Of Ion Transmembrane Transporter Activity Negative Regulation Of Protein Export From Nucleus Positive Regulation Of Transporter Activity Signaling Positive Regulation Of Ion Transport Cellular Homeostasis Regulation Of Blood Vessel Size Regulation Of Tube Size Positive Regulation Of Ion Transmembrane Transport Regulation Of Cation Channel Activity Signal Transduction G-protein Coupled Receptor Signaling Pathway G-protein Coupled Acetylcholine Receptor Signaling Pathway Learning Or Memory Response To Stimulus Glycerol Ether Metabolic Process Cell Redox Homeostasis Memory Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Regulation Of Cellular Process Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Secretion Learning Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Protein Export From Nucleus Vasoconstriction Developmental Process Vesicle Transport Along Microtubule Positive Regulation Of Adenylate Cyclase Activity Anatomical Structure Development Regulation Of Intracellular Transport Positive Regulation Of Receptor Activity Regulation Of Calcium Ion Transport Single-organism Behavior Response To Reactive Oxygen Species Nervous System Development Positive Regulation Of Signal Transduction
Tagcloud ?		alkenes azotic constructions gnai1 gnao1 heterocycle hm hms htr1b htr2a htr2b htr4 htr6 kpnb1 pharmacopeia prkaca prkca prkcb prkcd prkce prkcg prkd1 propertied pubchem rock2 rps6ka1 rps6ka3 tlr8 tradition
Tagcloud (Difference) ?		alkenes azotic constructions gnai1 gnao1 heterocycle hm hms htr1b htr2a htr2b htr4 htr6 kpnb1 pharmacopeia prkaca prkca prkcb prkcd prkce prkcg prkd1 propertied pubchem rock2 rps6ka1 rps6ka3 tlr8 tradition
Tagcloud (Intersection) ?