BTG1 and RNF181

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		BTG1	RNF181
Gene Name		B-cell translocation gene 1, anti-proliferative	ring finger protein 181
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	Transcription Cofactor Activity Protein Binding Enzyme Binding Kinase Binding	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity
	Biological Process	Regulation Of Transcription, DNA-templated Negative Regulation Of Cell Proliferation Cell Migration Negative Regulation Of Cell Growth Positive Regulation Of Endothelial Cell Differentiation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Angiogenesis Positive Regulation Of Fibroblast Apoptotic Process	Protein Autoubiquitination
Pathways
Drugs
Diseases
GWAS		Heart failure ( 20445134)	Prostate cancer ( 21743467)
Protein-Protein Interactions		12 interactors: CCNA2 CNOT7 CNOT8 HOXB9 PRMT1 RARA RNF181 SKP2 THRA THRB TUBA1A XRCC6	19 interactors: BIRC2 BTG1 CLK4 MRPS6 NPY5R PEG10 RBCK1 TRIM24 TRIM8 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2U VPS11 ZMYND10
Entrez ID		694	51255
HPRD ID		15912	14236
Ensembl ID
Uniprot IDs		P62324 Q6IBC8	Q9P0P0
PDB IDs
Enriched GO Terms of Interacting Partners?		Female Courtship Behavior Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Female Receptivity Positive Regulation Of Cellular Metabolic Process Female Mating Behavior Type I Pneumocyte Differentiation Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Gene Expression Regulation Of Transcription, DNA-templated G2/M Transition Of Mitotic Cell Cycle Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cell Proliferation Regulation Of RNA Metabolic Process Transcription, DNA-templated Hormone-mediated Signaling Pathway Positive Regulation Of MRNA Catabolic Process RNA Biosynthetic Process Positive Regulation Of Metabolic Process Nuclear-transcribed MRNA Poly(A) Tail Shortening Response To Steroid Hormone Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Transcription Initiation From RNA Polymerase II Promoter Mating Behavior Regulation Of Gene Expression Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Steroid Hormone Stimulus RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Cellular Response To Stimulus Intracellular Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Gene Silencing By MiRNA DNA-templated Transcription, Initiation Posttranscriptional Gene Silencing Mating Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Lung Epithelial Cell Differentiation Regulation Of Translation Respiratory System Development RNA Metabolic Process Lung Cell Differentiation Lung Epithelium Development Gene Silencing By RNA	Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Toll-like Receptor 4 Signaling Pathway Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Cellular Protein Modification Process Activation Of Innate Immune Response Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Cellular Macromolecule Catabolic Process Cellular Protein Metabolic Process Positive Regulation Of Innate Immune Response Protein K11-linked Ubiquitination Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Immune Response-regulating Signaling Pathway Regulation Of Innate Immune Response Cellular Response To Oxygen Levels Response To Hypoxia Catabolic Process Positive Regulation Of Protein Ubiquitination Protein Metabolic Process Positive Regulation Of Immune Response Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Proteolysis Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Ubiquitination Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Innate Immune Response Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Ligase Activity Negative Regulation Of Necroptotic Process
Tagcloud ?		accompanied achn adjacent bcell biopsies biopsy blotting empty endoscopic fraction g0 immediately indicator kidney lebtg1 leempty lentivirus lymphoma metalloproteinase proportion regulator respect serve stably transfected utilizing vectortransfected vs
Tagcloud (Difference) ?		accompanied achn adjacent bcell biopsies biopsy blotting empty endoscopic fraction g0 immediately indicator kidney lebtg1 leempty lentivirus lymphoma metalloproteinase proportion regulator respect serve stably transfected utilizing vectortransfected vs
Tagcloud (Intersection) ?