HRH2 and GPRASP2

Number of citations of the paper that reports this interaction (PMID 15086532)
18

Data Source:
HPRD (in vitro)

		HRH2	GPRASP2
Gene Name		histamine receptor H2	G protein-coupled receptor associated sorting protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Cytoplasm
	Molecular Function	Histamine Receptor Activity	Beta-amyloid Binding
	Biological Process	Histamine-induced Gastric Acid Secretion Gastrin-induced Gastric Acid Secretion Epithelial Cell Morphogenesis Immune Response G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Memory Visual Learning Positive Regulation Of Vasoconstriction Regulation Of Synaptic Plasticity Digestive Tract Development Gland Development Toxin Transport
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events Class A/1 (Rhodopsin-like receptors) Amine ligand-binding receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding Histamine receptors
Drugs		Betazole Cimetidine Nizatidine Histamine Phosphate Epinastine Ranitidine Famotidine Methantheline Doxepin Asenapine Metiamide Roxatidine acetate
Diseases
GWAS
Protein-Protein Interactions		1 interactors: GPRASP2	25 interactors: ADRB1 ARHGEF6 BARD1 BZRAP1 C6orf165 CALCR CBX8 CHRM1 CHRM2 DISC1 FRAT1 HAP1 HRH2 HTR7 HTT KIAA1377 LOC149950 LRIF1 MYOT PTN RPS6KA5 STMN2 TCF25 TXN TXN2
Entrez ID		3274	114928
HPRD ID		00816	06612
Ensembl ID		ENSG00000113749	ENSG00000158301
Uniprot IDs		P25021	B3KW05 Q96D09
PDB IDs
Enriched GO Terms of Interacting Partners?			G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Cell Surface Receptor Signaling Pathway Cell-cell Signaling Homeostatic Process Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Phospholipase C-activating G-protein Coupled Acetylcholine Receptor Signaling Pathway Positive Regulation Of Cation Channel Activity Cell Communication Cellular Response To Stimulus Cognition Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Synaptic Transmission Positive Regulation Of Ion Transmembrane Transporter Activity Negative Regulation Of Protein Export From Nucleus Positive Regulation Of Transporter Activity Signaling Positive Regulation Of Ion Transport Cellular Homeostasis Regulation Of Blood Vessel Size Regulation Of Tube Size Positive Regulation Of Ion Transmembrane Transport Regulation Of Cation Channel Activity Signal Transduction G-protein Coupled Receptor Signaling Pathway G-protein Coupled Acetylcholine Receptor Signaling Pathway Learning Or Memory Response To Stimulus Glycerol Ether Metabolic Process Cell Redox Homeostasis Memory Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Regulation Of Cellular Process Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Secretion Learning Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Protein Export From Nucleus Vasoconstriction Developmental Process Vesicle Transport Along Microtubule Positive Regulation Of Adenylate Cyclase Activity Anatomical Structure Development Regulation Of Intracellular Transport Positive Regulation Of Receptor Activity Regulation Of Calcium Ion Transport Single-organism Behavior Response To Reactive Oxygen Species Nervous System Development Positive Regulation Of Signal Transduction
Tagcloud ?		ablated amp arrays balb cha cholangiocarcinoma cholangiocytes cytosol dephosphorylation dihydrobromide erk1 excised extrahepatic histamine hrh1 hrh3 hrh4 inositol intrahepatic methylhistamine myo mz pkc pkcalpha ramh smears trisphosphate vegf visualized
Tagcloud (Difference) ?		ablated amp arrays balb cha cholangiocarcinoma cholangiocytes cytosol dephosphorylation dihydrobromide erk1 excised extrahepatic histamine hrh1 hrh3 hrh4 inositol intrahepatic methylhistamine myo mz pkc pkcalpha ramh smears trisphosphate vegf visualized
Tagcloud (Intersection) ?