HOXB5 and CSNK2B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HOXB5	CSNK2B
Description		homeobox B5	casein kinase 2 beta
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Fibrillar Center Nucleus Nucleoplasm Cytosol	Chromatin Fibrillar Center Extracellular Region Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Protein Kinase CK2 Complex PML Body PcG Protein Complex Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Chromatin Binding Protein Serine/threonine Kinase Activity Signaling Receptor Binding Protein Binding Protein Kinase Regulator Activity Protein Domain Specific Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Metal Ion Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Anterior/posterior Pattern Specification Endothelial Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Embryonic Skeletal System Development	Signal Transduction Negative Regulation Of Cell Population Proliferation Wnt Signaling Pathway Peptidyl-threonine Phosphorylation Release From Viral Latency Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Activin Receptor Signaling Pathway Adiponectin-activated Signaling Pathway Negative Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of SMAD Protein Signal Transduction Endothelial Tube Morphogenesis Protein-containing Complex Assembly Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Viral Life Cycle
Pathways			Synthesis of PC WNT mediated activation of DVL Condensation of Prometaphase Chromosomes Signal transduction by L1 Neutrophil degranulation Regulation of TP53 Activity through Phosphorylation Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding Receptor Mediated Mitophagy RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN stability and activity KEAP1-NFE2L2 pathway Regulation of CDH1 posttranslational processing and trafficking to plasma membrane Maturation of hRSV A proteins SPOP-mediated proteasomal degradation of PD-L1(CD274) Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK Phosphorylation and nuclear translocation of the CRY:PER:kinase complex
Drugs			ATP Quercetin
Diseases
GWAS		Diverticular disease ( 30177863) Obesity ( 22484627)	Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Cutaneous lupus erythematosus ( 25827949) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Systemic lupus erythematosus ( 26316170) Ulcerative colitis ( 28067908)
Interacting Genes		62 interacting genes: ASB6 AXIN2 CADPS CALCOCO2 CARD9 CCDC136 CCDC88B CEP70 CNFN CSNK2B CTBP1 CTBP2 CYSRT1 GOLGA2 GOLGA6A GOLGA6L9 HAP1 HOMER3 HOOK2 HSF2BP KIFAP3 KRT31 KRT34 KRTAP1-1 KRTAP10-6 KRTAP10-8 KRTAP6-3 LDOC1 MAGEA11 MEOX2 MID2 MTUS2 NFKBID OIP5 PBX1 PBX2 PBX4 PDE4DIP PHF19 PLXND1 PRDM14 RCHY1 TBC1D26 TEKT4 TEX11 TLE5 TRAF1 TRAF2 TRAF4 TRIB3 TRIM23 TRIM27 TRIM54 USH1G VPS52 ZC4H2 ZMYND12 ZNF286A ZNF552 ZNF655 ZNF774 ZRANB1	222 interacting genes: ABHD4 ACTB ACTL6B ACTR1B ACTR5 ACVRL1 ADD1 ADH5 ANGPT2 ANKRD28 AP2M1 APLP1 ARAF ATF1 ATG101 ATXN3 BAG6 BANP BCCIP BHLHE41 BID BMI1 BRCA1 BTF3 C6orf136 CACNA1A CALM1 CCDC187 CCNB1 CCNH CD163 CD81 CDC25B CDC34 CDK1 CDK20 CDKN1A CHEK1 CHRNA4 CIC CIPC CLOCK COIL COL4A2 COPS3 COPS7A CPNE7 CREB1 CSN1S1 CSN2 CSNK1E CSNK2A1 CSNK2A2 CST1 CTDP1 CTNNB1 DACT1 DALRD3 DAXX DELEC1 DENND5A DNMT1 DPF3 DSCAM DUX1 DYNLT2B EIF2S2 EIF5 EIF6 EPS8 ERCC6 ERCC8 ESR1 FAF1 FAM86C1P FBXL15 FBXL5 FGB FGF1 FGF2 FIBP FKBP3 FTH1 FXR1 FXR2 GADD45GIP1 GAMT GBP2 GLB1 GLIS2 GNB5 GRIN2A GRIN2B GRK2 GSK3B HEXB HNRNPA2B1 HOXB5 HOXB6 HTRA1 HYPK IER3IP1 INO80B INTS11 IRS1 ITSN1 KDM6B KIF2C LCK LEPR LMO4 LRP5L LTB4R2 LYN LYST MAPK14 MBD4 MDM2 MME MOXD1 MPP2 NAP1L1 NCF1 NGDN NMT2 NOLC1 NOTCH3 NPAS2 NRBP1 NRF1 NTAQ1 ODC1 OGA OGT PDS5A PER1 PER2 PFKFB4 PHF11 PIMREG PIN1 PITPNA PLXNA3 POT1 PPID PPP1CA PPP1CB PPP1CC PPP2CA PPP2R1A PPP2R1B PPP2R5D PPP2R5E PPP3CC PRKAB2 PRKCZ PRNP PROC PTPRK PTTG2 PYROXD2 RAD17 RAD51 RFC1 RNF126 RNF7 RORB RPA1 RPL13 RPL41 RPL5 RPS6KB1 RRAD RXRA SARNP SDHA SEC11A SELENOI SHMT1 SHMT2 SIMC1 SNX2 SPOUT1 SPSB3 SSB STAT5A STAU1 STK16 SUMO2 SYNE4 TCEAL7 TENM1 TFAP2A TFAP2D TLE1 TLX3 TNFAIP1 TOP2B TP53 TP53BP2 TP63 TRIM54 TSEN54 TUBB2B TWF1 UBE2I UPF1 USO1 UTP14A VDAC1 VMA22 VRK3 WDR1 WDR18 WFIKKN1 WWOX ZNF19 ZNF410 ZNF44 ZNF71 ZNF784 ZNHIT1
Entrez ID		3215	1460
HPRD ID		00848	00278
Ensembl ID		ENSG00000120075	ENSG00000204435
Uniprot IDs		P09067	A0A1U9X7J2 N0E4C7 P67870
PDB IDs			1DS5 1JWH 1QF8 3EED 4DGL 4MD7 4MD8 4MD9 4NH1 6Q38
Enriched GO Terms of Interacting Partners?		Protein Binding Thioesterase Binding Identical Protein Binding Intermediate Filament Keratin Filament Zinc Ion Binding Cytoskeleton Tumor Necrosis Factor Receptor Binding Signaling Adaptor Activity Microtubule Binding	Nucleus Nucleoplasm Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Cytosol Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Regulation Of DNA Metabolic Process Protein Binding Regulation Of Cell Cycle Cytoplasm Macromolecule Metabolic Process Positive Regulation Of DNA Metabolic Process DNA Damage Response Rhythmic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Metabolic Process Regulation Of Circadian Rhythm Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Phase Transition Regulation Of Gene Expression Chromosome Organization Regulation Of Transcription By RNA Polymerase II Response To Light Stimulus Regulation Of Cell Cycle Process Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Circadian Regulation Of Gene Expression Nucleic Acid Metabolic Process Circadian Rhythm Positive Regulation Of RNA Biosynthetic Process Regulation Of DNA-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Programmed Cell Death Photoperiodism Negative Regulation Of Metabolic Process DNA Damage Checkpoint Signaling Positive Regulation Of DNA-templated Transcription Negative Regulation Of Macromolecule Metabolic Process Cellular Response To Stress Response To Radiation Signal Transduction In Response To DNA Damage Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Biosynthetic Process Cellular Response To Oxygen-containing Compound Cell Cycle Phase Transition Intracellular Signal Transduction
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