HOXB5 and USH1G

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HOXB5	USH1G
Description		homeobox B5	USH1 protein network component sans
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Fibrillar Center Nucleus Nucleoplasm Cytosol	Photoreceptor Inner Segment Nucleus Cytoplasm Centrosome Cytosol Cytoskeleton Plasma Membrane Cilium Cajal Body Actin Cytoskeleton Membrane Nuclear Speck Photoreceptor Connecting Cilium Ciliary Basal Body Cell Projection Ciliary Base Photoreceptor Cell Cilium Plasma Membrane Bounded Cell Projection
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Spectrin Binding Identical Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Anterior/posterior Pattern Specification Endothelial Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Embryonic Skeletal System Development	Sensory Perception Of Sound Inner Ear Morphogenesis Photoreceptor Cell Maintenance Sensory Perception Of Light Stimulus Equilibrioception Inner Ear Receptor Cell Differentiation Inner Ear Receptor Cell Stereocilium Organization Regulation Of Clathrin-dependent Endocytosis
Pathways			Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases			Usher syndrome (US)
GWAS		Diverticular disease ( 30177863) Obesity ( 22484627)
Interacting Genes		62 interacting genes: ASB6 AXIN2 CADPS CALCOCO2 CARD9 CCDC136 CCDC88B CEP70 CNFN CSNK2B CTBP1 CTBP2 CYSRT1 GOLGA2 GOLGA6A GOLGA6L9 HAP1 HOMER3 HOOK2 HSF2BP KIFAP3 KRT31 KRT34 KRTAP1-1 KRTAP10-6 KRTAP10-8 KRTAP6-3 LDOC1 MAGEA11 MEOX2 MID2 MTUS2 NFKBID OIP5 PBX1 PBX2 PBX4 PDE4DIP PHF19 PLXND1 PRDM14 RCHY1 TBC1D26 TEKT4 TEX11 TLE5 TRAF1 TRAF2 TRAF4 TRIB3 TRIM23 TRIM27 TRIM54 USH1G VPS52 ZC4H2 ZMYND12 ZNF286A ZNF552 ZNF655 ZNF774 ZRANB1	19 interacting genes: AIRIM ANKRD11 BYSL CARD9 CBX8 DAXX DDX6 ENKD1 FAM161B GEM HOXB5 INO80B KIFC3 LMO2 PRKAA2 PRPF31 SCNM1 TCEANC USH1C
Entrez ID		3215	124590
HPRD ID		00848	09648
Ensembl ID		ENSG00000120075	ENSG00000182040
Uniprot IDs		P09067	B4DL95 Q495M9
PDB IDs			2L7T 3K1R 3PVL
Enriched GO Terms of Interacting Partners?		Protein Binding Thioesterase Binding Identical Protein Binding Intermediate Filament Keratin Filament Zinc Ion Binding Cytoskeleton Tumor Necrosis Factor Receptor Binding Signaling Adaptor Activity Microtubule Binding
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