HOXB5 and CNFN

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HOXB5	CNFN
Description		homeobox B5	cornifelin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Fibrillar Center Nucleus Nucleoplasm Cytosol	Cornified Envelope Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Anterior/posterior Pattern Specification Endothelial Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Embryonic Skeletal System Development	Keratinization
Pathways
Drugs
Diseases
GWAS		Diverticular disease ( 30177863) Obesity ( 22484627)
Interacting Genes		62 interacting genes: ASB6 AXIN2 CADPS CALCOCO2 CARD9 CCDC136 CCDC88B CEP70 CNFN CSNK2B CTBP1 CTBP2 CYSRT1 GOLGA2 GOLGA6A GOLGA6L9 HAP1 HOMER3 HOOK2 HSF2BP KIFAP3 KRT31 KRT34 KRTAP1-1 KRTAP10-6 KRTAP10-8 KRTAP6-3 LDOC1 MAGEA11 MEOX2 MID2 MTUS2 NFKBID OIP5 PBX1 PBX2 PBX4 PDE4DIP PHF19 PLXND1 PRDM14 RCHY1 TBC1D26 TEKT4 TEX11 TLE5 TRAF1 TRAF2 TRAF4 TRIB3 TRIM23 TRIM27 TRIM54 USH1G VPS52 ZC4H2 ZMYND12 ZNF286A ZNF552 ZNF655 ZNF774 ZRANB1	16 interacting genes: CCDC120 CREB5 EVX2 FAM222B HOXA1 HOXB5 HR KPRP SLC12A4 TCF7L2 TFAP2D TLE5 VGLL3 WDR25 ZNF414 ZNF581
Entrez ID		3215	84518
HPRD ID		00848	16729
Ensembl ID		ENSG00000120075	ENSG00000105427
Uniprot IDs		P09067	Q9BYD5
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Thioesterase Binding Identical Protein Binding Intermediate Filament Keratin Filament Zinc Ion Binding Cytoskeleton Tumor Necrosis Factor Receptor Binding Signaling Adaptor Activity Microtubule Binding	DNA-binding Transcription Factor Activity Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Chromatin DNA Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Semicircular Canal Formation Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Gene Expression Sequence-specific Double-stranded DNA Binding Abducens Nerve Formation RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Optokinetic Behavior Inferior Colliculus Development Beta-catenin-TCF7L2 Complex Catenin-TCF7L2 Complex Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Myoblast Fate Commitment
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