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HLA-E and PPP1R16A
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
HPRD
(two hybrid)
HLA-E
PPP1R16A
Gene Name
major histocompatibility complex, class I, E
protein phosphatase 1, regulatory subunit 16A
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Plasma Membrane
Cell Surface
ER To Golgi Transport Vesicle Membrane
Phagocytic Vesicle Membrane
Early Endosome Membrane
MHC Class I Protein Complex
Extracellular Vesicular Exosome
Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane
Plasma Membrane
Molecular Function
Receptor Binding
Beta-2-microglobulin Binding
MHC Class I Protein Binding
Peptide Antigen Binding
Protein Binding
Biological Process
Positive Regulation Of T Cell Mediated Cytotoxicity
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent
Regulation Of Natural Killer Cell Mediated Immunity
Positive Regulation Of Natural Killer Cell Mediated Immunity
Cytokine-mediated Signaling Pathway
Protection From Natural Killer Cell Mediated Cytotoxicity
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Innate Immune Response
Regulation Of Immune Response
Interferon-gamma-mediated Signaling Pathway
Type I Interferon Signaling Pathway
Pathways
DAP12 interactions
Interferon Signaling
Cytokine Signaling in Immune system
Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Interferon gamma signaling
DAP12 signaling
Endosomal/Vacuolar pathway
Interferon alpha/beta signaling
Class I MHC mediated antigen processing & presentation
Antigen processing-Cross presentation
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
ER-Phagosome pathway
Innate Immune System
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
7 interactors:
B2M
CALR
CD8A
KLRC1
KLRC2
KLRD1
PPP1R16A
20 interactors:
AES
CDH24
DDX27
FAM101B
FSD1
HGS
HLA-E
IDO1
LY6H
PAPSS1
PBDC1
PHPT1
PPP1CA
PPP1CB
PPP1CC
PUF60
RGMA
TPP2
TRIP6
TXNRD1
Entrez ID
3133
84988
HPRD ID
00877
16454
Ensembl ID
ENSG00000204592
ENSG00000160972
Uniprot IDs
A8K8M6
O19682
P13747
Q6DU44
Q96I34
PDB IDs
1KPR
1KTL
1MHE
2ESV
3AM8
3BZE
3BZF
3CDG
3CII
Enriched GO Terms of Interacting Partners
?
Regulation Of Immune System Process
Natural Killer Cell Mediated Immunity
Regulation Of Immune Response
Leukocyte Mediated Immunity
Antigen Processing And Presentation
Immune System Process
Immune Response
Signal Transduction
Defense Response
Signaling
Cell Communication
Peptide Antigen Assembly With MHC Class I Protein Complex
Cytotoxic T Cell Differentiation
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent
Response To Stress
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Cellular Response To Stimulus
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
T Cell Differentiation
Innate Immune Response
Sequestering Of Calcium Ion
Antigen Processing And Presentation Of Exogenous Protein Antigen Via MHC Class Ib, TAP-dependent
Antigen Processing And Presentation Of Peptide Antigen
Lymphocyte Differentiation
Positive Regulation Of Dendritic Cell Chemotaxis
Response To Stimulus
T Cell Aggregation
T Cell Activation
Lymphocyte Aggregation
Glucocorticoid Receptor Signaling Pathway
Leukocyte Aggregation
Protein Folding
Sequestering Of Metal Ion
Leukocyte Cell-cell Adhesion
Protein Maturation By Protein Folding
Response To Metal Ion
Homotypic Cell-cell Adhesion
Leukocyte Differentiation
Cell Surface Receptor Signaling Pathway
Lymphocyte Activation
Cellular Response To Lithium Ion
Protein Refolding
Metal Ion Homeostasis
Response To Inorganic Substance
Leukocyte Activation
Regulation Of Defense Response To Virus By Virus
Cortical Actin Cytoskeleton Organization
Response To Drug
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Positive Regulation Of Calcium-mediated Signaling
Entrainment Of Circadian Clock By Photoperiod
Triglyceride Catabolic Process
Photoperiodism
Entrainment Of Circadian Clock
Acylglycerol Catabolic Process
Regulation Of Glycogen Catabolic Process
Glycogen Metabolic Process
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Circadian Regulation Of Gene Expression
Polysaccharide Metabolic Process
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Protein Dephosphorylation
Regulation Of Circadian Rhythm
Triglyceride Metabolic Process
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Neutral Lipid Metabolic Process
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Negative Regulation Of Signal Transduction
Energy Reserve Metabolic Process
Transforming Growth Factor Beta Receptor Signaling Pathway
Cellular Lipid Catabolic Process
Regulation Of Glycogen Biosynthetic Process
Negative Regulation Of Signaling
Cell Division
Circadian Rhythm
Regulation Of Glycogen Metabolic Process
Regulation Of Cellular Response To Growth Factor Stimulus
Cellular Response To Transforming Growth Factor Beta Stimulus
Dephosphorylation
Response To Transforming Growth Factor Beta
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Carbohydrate Metabolic Process
Swimming Behavior
Kynurenic Acid Biosynthetic Process
Peptidyl-histidine Dephosphorylation
Regulation Of Signal Transduction
Lipid Catabolic Process
Regulation Of Generation Of Precursor Metabolites And Energy
Energy Derivation By Oxidation Of Organic Compounds
Rhythmic Process
Regulation Of Signaling
Adherens Junction Organization
Negative Regulation Of ATP Citrate Synthase Activity
Sulfate Assimilation
Cytokine Production Involved In Inflammatory Response
Protection From Natural Killer Cell Mediated Cytotoxicity
Response To Light Stimulus
Response To External Stimulus
Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib
Tagcloud
?
acaa1
analogous
ap1m2
aspirates
cgn
combat
dcn
ddr1
deadly
ec
ecs
efemp2
endometrial
eps8l2
fastkd1
gmip
ikbke
minimally
noncarcinoma
p2rx4
p4hb
phkg2
ppfibp2
rassf7
rnf183
sirt6
socs2
tjp3
uterine
Tagcloud (Difference)
?
acaa1
analogous
ap1m2
aspirates
cgn
combat
dcn
ddr1
deadly
ec
ecs
efemp2
endometrial
eps8l2
fastkd1
gmip
ikbke
minimally
noncarcinoma
p2rx4
p4hb
phkg2
ppfibp2
rassf7
rnf183
sirt6
socs2
tjp3
uterine
Tagcloud (Intersection)
?