PPP1R16A and PAPSS1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PPP1R16A	PAPSS1
Description		protein phosphatase 1 regulatory subunit 16A	3'-phosphoadenosine 5'-phosphosulfate synthase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane	Nucleus Cytoplasm Cytosol
	Molecular Function	Enzyme Inhibitor Activity Protein Binding Myosin Phosphatase Regulator Activity Protein Phosphatase Regulator Activity	Nucleotide Binding Catalytic Activity Adenylylsulfate Kinase Activity Sulfate Adenylyltransferase (ATP) Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Nucleotidyltransferase Activity Protein Homodimerization Activity
	Biological Process		Sulfate Assimilation Skeletal System Development 3'-phosphoadenosine 5'-phosphosulfate Biosynthetic Process
Pathways			Transport and metabolism of PAPS Metabolism of ingested H2SeO4 and H2SeO3 into H2Se Signaling by BRAF and RAF1 fusions
Drugs			Adenosine-5'-diphosphate-2',3'-vanadate Adenosine 5'-phosphosulfate Glycerin
Diseases
GWAS		Age at first birth ( 27798627) Blood metabolite levels ( 26401656) Educational attainment ( 25201988) Height ( 28552196) Mean corpuscular hemoglobin concentration ( 27863252 32888494)	Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) LDL cholesterol levels x loop diuretics use interaction ( 31806883) Telomere length ( 24478790)
Interacting Genes		52 interacting genes: ANTKMT ATP23 ATXN7L2 AVPI1 BATF2 C1orf216 C3orf36 CCDC116 CDCA7L CDH24 CKMT1A CKMT1B DDX27 FSD1 HDAC7 HGS HLA-E IDO1 IL16 KAT5 KRTAP19-5 LY6H LZTS2 MCCD1 MRPL12 MYOM1 NDUFAB1 NEK6 NUTF2 PAPSS1 PBDC1 PHPT1 PPP1CA PPP1CB PPP1CC PRKAB2 PRPF31 PUF60 RFLNB RGMA SCNM1 SUV39H1 TFIP11 TLE5 TPP2 TRIP6 TSSK3 TTC23 TXNRD1 UNKL ZFYVE26 ZNF414	4 interacting genes: EEF1A1 ERRFI1 PPP1R16A UNC119
Entrez ID		84988	9061
HPRD ID		16454	09132
Ensembl ID		ENSG00000160972	ENSG00000138801
Uniprot IDs		Q96I34	O43252
PDB IDs			1X6V 1XJQ 1XNJ 2OFW 2OFX 2PEY 2PEZ 2QJF 8I1M
Enriched GO Terms of Interacting Partners?		PTW/PP1 Phosphatase Complex Phosphocreatine Biosynthetic Process Creatine Kinase Activity Photoperiodism Entrainment Of Circadian Clock By Photoperiod Entrainment Of Circadian Clock	Regulation Of Protein Tyrosine Kinase Activity Response To Epidermal Growth Factor Cellular Response To Epidermal Growth Factor Stimulus Regulation Of Peptidyl-tyrosine Phosphorylation U6 2'-O-snRNA Methylation Kinase Binding Negative Regulation Of Caveolin-mediated Endocytosis Uterine Epithelium Development Response To 1-oleoyl-sn-glycerol 3-phosphate Eukaryotic Translation Elongation Factor 1 Complex Negative Regulation Of Clathrin-dependent Endocytosis Box C/D Sno(s)RNA 3'-end Processing Positive Regulation Of SnRNA Transcription By RNA Polymerase II 7SK SnRNP Negative Regulation Of Protein Autophosphorylation Oviduct Epithelium Development Response To Growth Factor Cellular Response To Growth Factor Stimulus Kinase Activator Activity Host-mediated Perturbation Of Viral Genome Replication Cytoplasmic Side Of Lysosomal Membrane Host-mediated Activation Of Viral Genome Replication Regulation Of Chaperone-mediated Autophagy Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Regulation Of Caveolin-mediated Endocytosis Positive Regulation Of Protein Tyrosine Kinase Activity SnRNA Modification 7SK SnRNA Binding Positive Regulation Of Protein Localization To Cajal Body U6 SnRNA Binding Skin Morphogenesis Negative Regulation Of Signaling Receptor Activity Lung Vasculature Development Limb Joint Morphogenesis Fat Pad Development Progesterone Receptor Signaling Pathway Regulation Of Type B Pancreatic Cell Proliferation Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Protein Tyrosine Kinase Activity Regulation Of Protein Autophosphorylation Myosin Phosphatase Regulator Activity Chondrocyte Proliferation Lung Epithelium Development Negative Regulation Of Collagen Biosynthetic Process Negative Regulation Of Viral Transcription Translation Elongation Factor Activity Lipoprotein Transport Regulation Of Protein Phosphorylation
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