PPP1R16A and IDO1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PPP1R16A	IDO1
Gene Name		protein phosphatase 1, regulatory subunit 16A	indoleamine 2,3-dioxygenase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane	Cytosol Smooth Muscle Contractile Fiber Stereocilium Bundle
	Molecular Function	Protein Binding	Tryptophan 2,3-dioxygenase Activity Electron Carrier Activity Heme Binding Indoleamine 2,3-dioxygenase Activity Metal Ion Binding
	Biological Process		Cytokine Production Involved In Inflammatory Response Positive Regulation Of T Cell Tolerance Induction Positive Regulation Of Chronic Inflammatory Response Positive Regulation Of Type 2 Immune Response Tryptophan Catabolic Process Female Pregnancy Tryptophan Catabolic Process To Kynurenine Response To Lipopolysaccharide Negative Regulation Of Interleukin-10 Production Positive Regulation Of Interleukin-12 Production Multicellular Organismal Response To Stress Kynurenic Acid Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Swimming Behavior Negative Regulation Of T Cell Proliferation Small Molecule Metabolic Process Regulation Of Activated T Cell Proliferation Oxidation-reduction Process Negative Regulation Of T Cell Apoptotic Process Positive Regulation Of T Cell Apoptotic Process
Pathways			Tryptophan catabolism Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: AES CDH24 DDX27 FAM101B FSD1 HGS HLA-E IDO1 LY6H PAPSS1 PBDC1 PHPT1 PPP1CA PPP1CB PPP1CC PUF60 RGMA TPP2 TRIP6 TXNRD1	4 interactors: APP DDX24 PPP1R16A TERF2IP
Entrez ID		84988	3620
HPRD ID		16454	00935
Ensembl ID		ENSG00000160972
Uniprot IDs		Q96I34	P14902
PDB IDs			2D0T 2D0U
Enriched GO Terms of Interacting Partners?		Entrainment Of Circadian Clock By Photoperiod Triglyceride Catabolic Process Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Regulation Of Glycogen Catabolic Process Glycogen Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Circadian Regulation Of Gene Expression Polysaccharide Metabolic Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Protein Dephosphorylation Regulation Of Circadian Rhythm Triglyceride Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Neutral Lipid Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Signal Transduction Energy Reserve Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Lipid Catabolic Process Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Signaling Cell Division Circadian Rhythm Regulation Of Glycogen Metabolic Process Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Dephosphorylation Response To Transforming Growth Factor Beta Enzyme Linked Receptor Protein Signaling Pathway Cellular Carbohydrate Metabolic Process Swimming Behavior Kynurenic Acid Biosynthetic Process Peptidyl-histidine Dephosphorylation Regulation Of Signal Transduction Lipid Catabolic Process Regulation Of Generation Of Precursor Metabolites And Energy Energy Derivation By Oxidation Of Organic Compounds Rhythmic Process Regulation Of Signaling Adherens Junction Organization Negative Regulation Of ATP Citrate Synthase Activity Sulfate Assimilation Cytokine Production Involved In Inflammatory Response Protection From Natural Killer Cell Mediated Cytotoxicity Response To Light Stimulus Response To External Stimulus Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib	Negative Regulation Of DNA Recombination At Telomere Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Protection From Non-homologous End Joining At Telomere Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Telomere Capping Protein Localization To Chromosome, Telomeric Region Axon Choice Point Recognition Neuron Remodeling Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Double-strand Break Repair Via Homologous Recombination Cellular Copper Ion Homeostasis Regulation Of Telomere Maintenance RNA Metabolic Process RNA-dependent DNA Replication Copper Ion Homeostasis Suckling Behavior Negative Regulation Of DNA Recombination Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Double-strand Break Repair Protein Localization To Chromosome Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Telomere Maintenance Via Telomere Lengthening Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Neuron Apoptotic Process Positive Regulation Of Cell Cycle Phase Transition Nucleobase-containing Compound Metabolic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Regulation Of DNA Repair Visual Behavior Neuron Death Heterocycle Metabolic Process
Tagcloud ?		acaa1 analogous ap1m2 aspirates cgn combat dcn ddr1 deadly ec ecs efemp2 endometrial eps8l2 fastkd1 gmip ikbke minimally noncarcinoma p2rx4 p4hb phkg2 ppfibp2 rassf7 rnf183 sirt6 socs2 tjp3 uterine	anthracycline assignment bcs carboplatin cb ccl5 cd21 cd80 cd8a ctla4 cxcl13 cxcl9 foxp3 geparsixto hierarchic histopathologic igkc immunogenicity immunologic immunologically infiltrating lpbc ors pmcb standardization taxane tils tn univariable
Tagcloud (Difference) ?		acaa1 analogous ap1m2 aspirates cgn combat dcn ddr1 deadly ec ecs efemp2 endometrial eps8l2 fastkd1 gmip ikbke minimally noncarcinoma p2rx4 p4hb phkg2 ppfibp2 rassf7 rnf183 sirt6 socs2 tjp3 uterine	anthracycline assignment bcs carboplatin cb ccl5 cd21 cd80 cd8a ctla4 cxcl13 cxcl9 foxp3 geparsixto hierarchic histopathologic igkc immunogenicity immunologic immunologically infiltrating lpbc ors pmcb standardization taxane tils tn univariable
Tagcloud (Intersection) ?