PPP1R16A and IDO1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PPP1R16A	IDO1
Description		protein phosphatase 1 regulatory subunit 16A	indoleamine 2,3-dioxygenase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane	Cytoplasm Cytosol Smooth Muscle Contractile Fiber Stereocilium Bundle
	Molecular Function	Enzyme Inhibitor Activity Protein Binding Myosin Phosphatase Regulator Activity Protein Phosphatase Regulator Activity	Tryptophan 2,3-dioxygenase Activity Electron Transfer Activity Oxidoreductase Activity Heme Binding Indoleamine 2,3-dioxygenase Activity Metal Ion Binding Dioxygenase Activity
	Biological Process		Immune System Process Positive Regulation Of T Cell Tolerance Induction Positive Regulation Of Chronic Inflammatory Response Positive Regulation Of Type 2 Immune Response L-tryptophan Catabolic Process Inflammatory Response Female Pregnancy L-tryptophan Catabolic Process To Kynurenine Quinolinate Biosynthetic Process Response To Lipopolysaccharide Negative Regulation Of Interleukin-10 Production Positive Regulation Of Interleukin-12 Production Multicellular Organismal Response To Stress Kynurenic Acid Biosynthetic Process 'de Novo' NAD+ Biosynthetic Process From L-tryptophan Swimming Behavior T Cell Proliferation Negative Regulation Of T Cell Proliferation Positive Regulation Of Apoptotic Process Regulation Of Activated T Cell Proliferation Negative Regulation Of T Cell Apoptotic Process Positive Regulation Of T Cell Apoptotic Process
Pathways			Tryptophan catabolism
Drugs			Nitric Oxide Cannabidiol Medical Cannabis Nabiximols
Diseases
GWAS		Age at first birth ( 27798627) Blood metabolite levels ( 26401656) Educational attainment ( 25201988) Height ( 28552196) Mean corpuscular hemoglobin concentration ( 27863252 32888494)
Interacting Genes		52 interacting genes: ANTKMT ATP23 ATXN7L2 AVPI1 BATF2 C1orf216 C3orf36 CCDC116 CDCA7L CDH24 CKMT1A CKMT1B DDX27 FSD1 HDAC7 HGS HLA-E IDO1 IL16 KAT5 KRTAP19-5 LY6H LZTS2 MCCD1 MRPL12 MYOM1 NDUFAB1 NEK6 NUTF2 PAPSS1 PBDC1 PHPT1 PPP1CA PPP1CB PPP1CC PRKAB2 PRPF31 PUF60 RFLNB RGMA SCNM1 SUV39H1 TFIP11 TLE5 TPP2 TRIP6 TSSK3 TTC23 TXNRD1 UNKL ZFYVE26 ZNF414	5 interacting genes: APP DDX24 FBXL17 PPP1R16A TERF2IP
Entrez ID		84988	3620
HPRD ID		16454	00935
Ensembl ID		ENSG00000160972	ENSG00000131203
Uniprot IDs		Q96I34	A0A348GSI3 P14902
PDB IDs			2D0T 2D0U 4PK5 4PK6 4U72 4U74 5EK2 5EK3 5EK4 5ETW 5WHR 5WMU 5WMV 5WMW 5WMX 5WN8 5XE1 6AZU 6AZV 6AZW 6CXU 6CXV 6DPQ 6DPR 6E35 6E40 6E41 6E42 6E43 6E44 6E45 6E46 6F0A 6KOF 6KPS 6KW7 6MQ6 6O3I 6PU7 6PZ1 6R63 6UBP 6V52 6WJY 6WPE 6X5Y 7A62 7AH4 7AH5 7AH6 7B1O 7E0O 7E0P 7E0Q 7E0S 7E0T 7E0U 7M63 7M7D 7NGE 7P0N 7P0R 7RRB 7RRC 7RRD 7YXT 7Z2L 7ZV3 8ABX 8FUR 8I7L 8U5I 9ESB 9ESC 9ESE 9ESG
Enriched GO Terms of Interacting Partners?		PTW/PP1 Phosphatase Complex Phosphocreatine Biosynthetic Process Creatine Kinase Activity Photoperiodism Entrainment Of Circadian Clock By Photoperiod Entrainment Of Circadian Clock
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