N4BP2L2

Description		NEDD4 binding protein 2 like 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Transcription Repressor Complex Extracellular Exosome
	Molecular Function	Transcription Corepressor Activity Protein Binding Enzyme Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Blastocyst Development Positive Regulation Of Hematopoietic Stem Cell Proliferation Negative Regulation Of Hematopoietic Stem Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Breast cancer ( 23535729) Coronary artery disease ( 29212778 33020668) Heel bone mineral density ( 30598549) LDL cholesterol ( 30275531) Logical memory (delayed recall) ( 29274321) Myocardial infarction ( 33532862)
Novel Interacting Genes		1 novel interacting genes: EXOSC8
Interacting Genes		7 interacting genes: HOXA1 HUNK LMO2 NAA38 PPIA PPIH PPIL1
Entrez ID		10443
HPRD ID		15119
Ensembl ID		ENSG00000244754
Uniprot IDs		A0A6I8PRE0 A0A6I8PRM1 A0A6I8PRR0 A0A6I8PS46 B4DPY1 Q6ZV26 Q92802
PDB IDs
Enriched GO Terms of Interacting Partners?		Peptidyl-prolyl Cis-trans Isomerase Activity Protein Peptidyl-prolyl Isomerization Cyclosporin A Binding Isomerase Activity Protein Folding Positive Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Semicircular Canal Formation Regulation Of Viral Genome Replication Abducens Nerve Formation Optokinetic Behavior Negative Regulation Of Protein K48-linked Ubiquitination NatC Complex Regulation Of Viral Life Cycle Cell Adhesion Molecule Production U4/U6 SnRNP U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing Regulation Of Viral Process MRNA Metabolic Process Outer Ear Morphogenesis Embryonic Neurocranium Morphogenesis Virion Binding Regulation Of Protein K48-linked Ubiquitination Activation Of Protein Kinase B Activity Negative Regulation Of Viral Life Cycle Endothelial Cell Activation Heparan Sulfate Binding Negative Regulation Of Protein Polyubiquitination Negative Regulation Of Stress-activated Protein Kinase Signaling Cascade Negative Regulation Of Stress-activated MAPK Cascade MRNA Splicing, Via Spliceosome Spliceosomal Complex RNA Splicing, Via Transesterification Reactions Exoribonuclease Complex Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) TRAMP-dependent TRNA Surveillance Pathway TRNA Surveillance RRNA 3'-end Processing Nucleolar Exosome (RNase Complex) U4 SnRNA 3'-end Processing Nuclear Polyadenylation-dependent RRNA Catabolic Process TRNA Decay Nuclear MRNA Surveillance Nucleus RNA Processing Cytoplasmic Exosome (RNase Complex) RNA Exonuclease Activity RRNA Catabolic Process Nuclear Exosome (RNase Complex)
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