KIAA1377 and POLR2M

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KIAA1377	POLR2M
Gene Name		KIAA1377	polymerase (RNA) II (DNA directed) polypeptide M
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome Midbody Ciliary Base	Nuclear Envelope DNA-directed RNA Polymerase II, Holoenzyme Neuronal Cell Body
	Molecular Function	Protein Binding	DNA-directed RNA Polymerase Activity
	Biological Process	Mitotic Spindle Organization Cytoplasmic Microtubule Organization Cilium Assembly	RNA Biosynthetic Process Maintenance Of ER Location
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		86 interactors: AIMP2 AKTIP ARIH2 ATP6V1F ATRX BMI1 BRD1 C11orf58 CDKN2B CRCT1 CSTF2 DGCR6 DISC1 DLEU1 DNM1 DUSP12 DUSP23 EIF2S2 EIF6 EPN1 FAM118B FAM134A FEZ1 FGFR3 FXR1 GEMIN7 GET4 GIT1 GOLGB1 GPRASP2 GSTO1 HMOX2 HTT ING5 KAT5 KAT7 KIF15 KLHL20 LAMTOR5 LPL LRRC1 LUC7L2 MAD2L1BP MAPK9 MRPS6 NAP1L5 NAT9 NPM3 NSF NUDT21 ODF2L OFD1 PBK PDCD5 PFDN1 PIK3R3 PMF1 POLD1 POLR2M PPP1CA PPP1CC PRKRA PTPRS RAB27A RAN RBM23 RGS2 RIF1 ROGDI RPA2 RUVBL1 SAT1 SNRPG SPDL1 STAU2 TFG TNFRSF14 TNFSF11 TOMM20 TTR TXNDC9 VIM YAE1D1 YWHAZ ZBED8 ZNF24	19 interactors: AHSP ANKHD1 APOD CEBPG DGKZ HIGD1B KIAA1377 MYO3A MYO9A NEDD4 PSMC2 RBM4B RPL7A SCMH1 SIVA1 THAP1 UQCRQ WDR89 ZNF410
Entrez ID		57562	81488
HPRD ID		17212	07575
Ensembl ID		ENSG00000110318	ENSG00000255529
Uniprot IDs		Q9P2H0	P0CAP1 P0CAP2 Q6EEV4
PDB IDs			2KXS
Enriched GO Terms of Interacting Partners?		Organelle Organization Cell Cycle Mitotic Cell Cycle Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Cellular Metabolic Process Mitotic Cell Cycle Process Cellular Process Response To Light Stimulus Response To Radiation Triglyceride Catabolic Process Gene Expression Positive Regulation Of Apoptotic Signaling Pathway Organelle Localization Acylglycerol Catabolic Process Endomembrane System Organization Establishment Of Organelle Localization Cell Cycle Process Positive Regulation Of Signal Transduction Peptidyl-lysine Modification Endosome Organization Protein Localization To Organelle Positive Regulation Of Metabolic Process Anatomical Structure Development System Development Regulation Of Signal Transduction Termination Of RNA Polymerase II Transcription Cytoplasmic Transport Programmed Cell Death Chromosome Organization Cell Division Ribosomal Subunit Export From Nucleus Cell Death Regulation Of Signaling Cellular Response To Stimulus Death Histone H3 Acetylation Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Protein Ubiquitination Mitotic Nuclear Division Ribonucleoprotein Complex Biogenesis Response To Abiotic Stimulus Positive Regulation Of Striated Muscle Contraction Cellular Response To Organic Substance RNA Metabolic Process Organ Development Neurotransmitter Uptake	Viral Process Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Negative Regulation Of T Cell Migration Negative Regulation Of Lipoprotein Lipid Oxidation Transmission Of Virus Development Involved In Symbiotic Interaction Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Negative Regulation Of Smooth Muscle Cell-matrix Adhesion Subthalamus Development Negative Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Lipoprotein Lipid Oxidation Mitotic DNA Damage Checkpoint Regulation Of Smooth Muscle Cell-matrix Adhesion Negative Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Interaction With Host Regulation Of Mitotic Cell Cycle Negative Regulation Of Lymphocyte Migration Regulation Of Intracellular Transport Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Progesterone Receptor Signaling Pathway Developmental Process
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