CEP126 and NUDT21

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		CEP126	NUDT21
Description		centrosomal protein 126	nudix hydrolase 21
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytoskeleton Midbody Cell Projection Ciliary Base	Nucleus Nucleoplasm Cytoplasm Centrosome MRNA Cleavage And Polyadenylation Specificity Factor Complex MRNA Cleavage Factor Complex Nuclear Body Centriolar Satellite Paraspeckles
	Molecular Function	Protein Binding	Chromatin Binding RNA Binding MRNA Binding Protein Binding MRNA 3'-UTR AU-rich Region Binding Identical Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding
	Biological Process	Mitotic Spindle Organization Cell Projection Organization Cytoplasmic Microtubule Organization Cilium Assembly Non-motile Cilium Assembly	MRNA Processing Post-transcriptional Regulation Of Gene Expression Cell Differentiation MRNA 3'-end Processing Protein Tetramerization Protein Heterotetramerization MRNA Alternative Polyadenylation Co-transcriptional MRNA 3'-end Processing, Cleavage And Polyadenylation Pathway Positive Regulation Of Stem Cell Differentiation Positive Regulation Of Pro-B Cell Differentiation
Pathways			mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS
Interacting Genes		87 interacting genes: AIMP2 AKTIP ARIH2 ATP6V1F ATRX BMI1 BRD1 C11orf58 CDKN2B CRCT1 CSTF2 DGCR6 DISC1 DLEU1 DNM1 DUSP12 DUSP23 EIF2S2 EIF6 EPN1 FAM118B FAM200C FEZ1 FGFR3 FXR1 GEMIN7 GET4 GIT1 GOLGB1 GPRASP2 GSTO1 HMOX2 HTT ING5 KAT5 KAT7 KIF15 KLHL20 LAMTOR5 LPL LRRC1 LUC7L2 MAD2L1BP MAPK9 MLH1 MRPS6 NAP1L5 NAT9 NPM3 NSF NUDT21 ODF2L OFD1 PBK PDCD5 PFDN1 PIK3R3 PMF1 POLD1 POLR2M PPP1CA PPP1CC PRKRA PTPRS RAB27A RAN RBM23 RETREG2 RGS2 RIF1 ROGDI RPA2 RUVBL1 SAT1 SNRPG SPDL1 STAU2 TFG TNFRSF14 TNFSF11 TOMM20 TTR TXNDC9 VIM YAE1 YWHAZ ZNF24	119 interacting genes: A2M ATXN1 CARM1 CDC42 CEBPA CEP126 CLP1 CPSF6 CPSF7 CTNND2 DBN1 DNMT3L DYNC1I1 EED EEF1G ESR1 EXOSC6 F13A1 FAM90A1 FBN3 FLAD1 FUNDC2 GOLGA2 HSF4 IKZF1 ITCH JMJD1C KIFAP3 KRT75 MASP1 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-2 MIR138-1 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200B MIR205 MIR206 MIR20A MIR214 MIR221 MIR25 MIR29A MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-2 MIR9-2 MIR92A1 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MYL6 NEDD4 NGEF NIF3L1 NTAQ1 POLR2C PSMF1 PSPC1 PTN PYCR1 RBM48 RCC1 RNF19A RPLP1 S100PBP SEM1 SEMA5B SF3B1 SHC1 SLC44A1 SNCAIP SNRNP70 SPAG8 SRPK1 TCERG1 TEPSIN TLE1 TRA2A TRIM23 TRIM27 WWOX ZNF655
Entrez ID		57562	11051
HPRD ID		17212	05400
Ensembl ID		ENSG00000110318	ENSG00000167005
Uniprot IDs		Q9P2H0	O43809
PDB IDs			2CL3 2J8Q 3BAP 3BHO 3MDG 3MDI 3N9U 3P5T 3P6Y 3Q2S 3Q2T 5R4P 5R4Q 5R4R 5R4S 5R4T 5R4U 5R64 5R65 5R66 5R67
Enriched GO Terms of Interacting Partners?		Nucleus Organelle Organization Cytosol Histone H3-K14 Acetyltransferase Complex Protein Binding Establishment Of Organelle Localization Phosphoprotein Phosphatase Activity Microtubule Cytoskeleton Organization Involved In Mitosis Protein-RNA Complex Assembly DNA Replication-dependent Chromatin Disassembly Organelle Localization Cytoplasm Chromatin Binding Presynapse Axon Positive Regulation Of Aggrephagy Histone Acetyltransferase Complex DNA Repair Chromosome, Telomeric Region Regulation Of Circadian Rhythm Chromosome Organization	MiRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex MRNA Base-pairing Post-transcriptional Repressor Activity Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Extracellular Vesicle MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Translation Regulation Of Angiogenesis Regulation Of Vasculature Development Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Blood Vessel Endothelial Cell Migration MRNA Destabilization Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Migration RNA Destabilization Negative Regulation Of Cytokine Production Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Cell Motility Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Locomotion Regulation Of Macromolecule Metabolic Process Regulation Of Endothelial Cell Migration Negative Regulation Of Multicellular Organismal Process Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Endothelial Cell Migration Positive Regulation Of Tissue Remodeling Negative Regulation Of Developmental Process Negative Regulation Of Sprouting Angiogenesis Regulation Of Metabolic Process Positive Regulation Of Connective Tissue Replacement Regulation Of Translation Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Anatomical Structure Morphogenesis Negative Regulation Of Signal Transduction Regulation Of Sprouting Angiogenesis Negative Regulation Of Protein Metabolic Process
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