DNMT3L and RSL24D1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		DNMT3L	RSL24D1
Gene Name		DNA (cytosine-5-)-methyltransferase 3-like	ribosomal L24 domain containing 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol	Nucleus Nucleolus
	Molecular Function	Protein Binding Enzyme Activator Activity Enzyme Binding Metal Ion Binding
	Biological Process	DNA Methylation Regulation Of Gene Expression By Genetic Imprinting Spermatogenesis Gene Expression DNA Methylation On Cytosine Regulation Of Gene Expression, Epigenetic Positive Regulation Of Catalytic Activity Negative Regulation Of Transcription, DNA-templated	Ribosome Biogenesis
Pathways		Epigenetic regulation of gene expression DNA methylation
Drugs
Diseases
GWAS			Neutrophil count ( 21507922)
Protein-Protein Interactions		11 interactors: DNMT3A DNMT3B GSK3B HDAC1 HIST2H2AC HIST2H2BE HIST2H3C HIST2H4A NUDT21 PHPT1 RSL24D1	4 interactors: CDC23 DNMT3L FAM9B LSM8
Entrez ID		29947	51187
HPRD ID		09417	12665
Ensembl ID		ENSG00000142182
Uniprot IDs		Q9UJW3	Q9UHA3
PDB IDs		2PV0 2PVC 2QRV
Enriched GO Terms of Interacting Partners?		DNA Methylation On Cytosine Negative Regulation Of Gene Expression, Epigenetic Regulation Of Gene Expression, Epigenetic Chromatin Silencing DNA Methylation DNA Modification Gene Silencing Regulation Of Gene Expression By Genetic Imprinting Genetic Imprinting S-adenosylmethioninamine Metabolic Process Hypermethylation Of CpG Island DNA Methylation On Cytosine Within A CG Sequence C-5 Methylation Of Cytosine S-adenosylhomocysteine Metabolic Process Methylation-dependent Chromatin Silencing Chromatin Organization Negative Regulation Of Biosynthetic Process Chromatin Silencing At RDNA Methylation Regulation Of DNA Methylation Chromosome Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromatin Modification Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Cellular Response To Amino Acid Stimulus ATP-dependent Chromatin Remodeling Peptidyl-histidine Dephosphorylation Negative Regulation Of Type B Pancreatic Cell Development Superior Temporal Gyrus Development DNA Metabolic Process Response To Amino Acid Re-entry Into Mitotic Cell Cycle Histone H4-K20 Demethylation Negative Regulation Of ATP Citrate Synthase Activity Negative Regulation Of Neuron Maturation Nucleosome Assembly Nucleobase-containing Compound Metabolic Process Chromatin Assembly Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Nucleosome Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Chromatin Assembly Or Disassembly Negative Regulation Of Megakaryocyte Differentiation Cellular Response To Interleukin-3 Protein-DNA Complex Assembly	Metaphase/anaphase Transition Of Mitotic Cell Cycle Regulation Of Exit From Mitosis DNA Methylation On Cytosine Protein K11-linked Ubiquitination Mitotic Metaphase Plate Congression Regulation Of Gene Expression By Genetic Imprinting Metaphase Plate Congression Mitotic Spindle Assembly Checkpoint Genetic Imprinting Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Establishment Of Chromosome Localization Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition DNA Methylation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Proteasomal Protein Catabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Ligase Activity Mitotic Sister Chromatid Segregation Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Sister Chromatid Segregation DNA Modification Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Chromosome Organization Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Catalytic Activity Negative Regulation Of Protein Ubiquitination
Tagcloud ?		add adds atrx autoinhibition autoinhibitory catalytically connection disrupts embryogenesis enzymatic h3k4 h3k4me0 h3k4me3 imprinting inheritance methyltransferase methyltransferases novo paralogue positioning recognizes releases stimulates tail unexpected unmethylated	actb arfgap2 arl1 bestkeeper bmi1 casc3 cynomolgus ddx3x gapdh genorm lists monkey morf4 mrfap1 normalization normfinder ormdl1 prerequisite reference ribosylation rps19 sar1a traditionally transcriptome usp22 vitally ywhaz zc3h11a zranb2
Tagcloud (Difference) ?		add adds atrx autoinhibition autoinhibitory catalytically connection disrupts embryogenesis enzymatic h3k4 h3k4me0 h3k4me3 imprinting inheritance methyltransferase methyltransferases novo paralogue positioning recognizes releases stimulates tail unexpected unmethylated	actb arfgap2 arl1 bestkeeper bmi1 casc3 cynomolgus ddx3x gapdh genorm lists monkey morf4 mrfap1 normalization normfinder ormdl1 prerequisite reference ribosylation rps19 sar1a traditionally transcriptome usp22 vitally ywhaz zc3h11a zranb2
Tagcloud (Intersection) ?