DNMT3L

Gene Name		DNA (cytosine-5-)-methyltransferase 3-like
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Gene Ontology Annotations	Cellular Component	Nucleus Cytosol
	Molecular Function	Protein Binding Enzyme Activator Activity Enzyme Binding Metal Ion Binding
	Biological Process	DNA Methylation Regulation Of Gene Expression By Genetic Imprinting Spermatogenesis Gene Expression DNA Methylation On Cytosine Regulation Of Gene Expression, Epigenetic Positive Regulation Of Catalytic Activity Negative Regulation Of Transcription, DNA-templated
Pathways		Epigenetic regulation of gene expression DNA methylation
Drugs
Diseases
GWAS
Protein-protein Interactions		11 interactors: DNMT3A DNMT3B GSK3B HDAC1 HIST2H2AC HIST2H2BE HIST2H3C HIST2H4A NUDT21 PHPT1 RSL24D1
Entrez ID		29947
HPRD ID		09417
Ensembl ID		ENSG00000142182
Uniprot IDs		Q9UJW3
PDB IDs		2PV0 2PVC 2QRV
Enriched GO Terms of Interacting Partners?		DNA Methylation On Cytosine Negative Regulation Of Gene Expression, Epigenetic Regulation Of Gene Expression, Epigenetic Chromatin Silencing DNA Methylation DNA Modification Gene Silencing Regulation Of Gene Expression By Genetic Imprinting Genetic Imprinting S-adenosylmethioninamine Metabolic Process Hypermethylation Of CpG Island DNA Methylation On Cytosine Within A CG Sequence C-5 Methylation Of Cytosine S-adenosylhomocysteine Metabolic Process Methylation-dependent Chromatin Silencing Chromatin Organization Negative Regulation Of Biosynthetic Process Chromatin Silencing At RDNA Methylation Regulation Of DNA Methylation Chromosome Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromatin Modification Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Cellular Response To Amino Acid Stimulus ATP-dependent Chromatin Remodeling Peptidyl-histidine Dephosphorylation Negative Regulation Of Type B Pancreatic Cell Development Superior Temporal Gyrus Development DNA Metabolic Process Response To Amino Acid Re-entry Into Mitotic Cell Cycle Histone H4-K20 Demethylation Negative Regulation Of ATP Citrate Synthase Activity Negative Regulation Of Neuron Maturation Nucleosome Assembly Nucleobase-containing Compound Metabolic Process Chromatin Assembly Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Nucleosome Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Chromatin Assembly Or Disassembly Negative Regulation Of Megakaryocyte Differentiation Cellular Response To Interleukin-3 Protein-DNA Complex Assembly
Tagcloud ?		add adds atrx autoinhibition autoinhibitory catalytically connection disrupts embryogenesis enzymatic h3k4 h3k4me0 h3k4me3 imprinting inheritance methyltransferase methyltransferases novo paralogue positioning recognizes releases stimulates tail unexpected unmethylated