REPIN1 and GMNN

Number of citations of the paper that reports this interaction (PMID 16924111)
21

Data Source:
BioGRID (pull down)

		REPIN1	GMNN
Gene Name		replication initiator 1	geminin, DNA replication inhibitor
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Origin Of Replication Recognition Complex Lipid Particle Cytosolic Ribosome Nuclear Membrane	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	DNA Binding Poly(A) RNA Binding Metal Ion Binding	Transcription Corepressor Activity Protein Binding Histone Deacetylase Binding Repressing Transcription Factor Binding
	Biological Process	DNA Replication Regulation Of Fatty Acid Transport Regulation Of Glucose Import In Response To Insulin Stimulus	Mitotic Cell Cycle Protein Complex Assembly Negative Regulation Of DNA Replication Organ Morphogenesis Negative Regulation Of Cell Cycle Negative Regulation Of Transcription, DNA-templated
Pathways			DNA Replication Pre-Initiation M/G1 Transition Regulation of DNA replication Removal of licensing factors from origins CDT1 association with the CDC6:ORC:origin complex Association of licensing factors with the pre-replicative complex Cell Cycle, Mitotic Assembly of the pre-replicative complex
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: GATA3 GMNN HDAC1	26 interactors: ARNT AURKA CASP3 CCDC146 CDKN1A CDKN2A CDT1 CSNK2A1 HDAC1 HOXA10 HOXA11 HOXA7 HOXB7 HOXC8 HOXC9 HOXD10 IMPDH1 KAT7 MCM6 NCF1 PHC1 REPIN1 SCMH1 SIX3 SMARCA4 ZNF439
Entrez ID		29803	51053
HPRD ID		17966	06783
Ensembl ID		ENSG00000214022	ENSG00000112312
Uniprot IDs		C9J3L7 Q9BWE0	O75496
PDB IDs			1T6F 1UII 2LP0 2WVR 4BRY
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cell Cycle Regulation Of Cell Cycle Organ Morphogenesis Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Parathyroid Hormone Secretion Negative Regulation Of Cell Proliferation Involved In Mesonephros Development Type IV Hypersensitivity Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Ureteric Bud Formation Negative Regulation Of Glial Cell-derived Neurotrophic Factor Receptor Signaling Pathway Involved In Ureteric Bud Formation Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Canonical Wnt Signaling Pathway Involved In Metanephric Kidney Development Pro-T Cell Differentiation Regulation Of Cellular Response To X-ray Mast Cell Differentiation Positive Regulation Of Thyroid Hormone Generation Ureteric Bud Formation Positive Regulation Of Ureteric Bud Formation T-helper 2 Cell Differentiation Aortic Valve Morphogenesis Nephric Duct Formation Negative Regulation Of Cell Proliferation Involved In Kidney Development Ureter Maturation Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Norepinephrine Biosynthetic Process Camera-type Eye Development Negative Regulation Of Cellular Metabolic Process Regulation Of Thyroid Hormone Generation Eye Development Blood Coagulation Hemostasis Interleukin-4 Secretion Interferon-gamma Secretion Nephric Duct Morphogenesis Mesonephric Tubule Formation Positive Regulation Of Transcription Regulatory Region DNA Binding Anatomical Structure Morphogenesis Acute Inflammatory Response To Antigenic Stimulus Cellular Response To Interferon-alpha Positive Regulation Of Receptor Biosynthetic Process Parathyroid Gland Development Type 2 Immune Response Negative Regulation By Host Of Viral Transcription Interleukin-4 Production Lymphoid Progenitor Cell Differentiation Epithelial Cell Differentiation Norepinephrine Metabolic Process Positive Regulation Of Interleukin-13 Secretion	Anterior/posterior Pattern Specification Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Macromolecule Biosynthetic Process Pattern Specification Process Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Embryonic Morphogenesis Anatomical Structure Morphogenesis Gene Expression Embryonic Organ Development Embryonic Organ Morphogenesis Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Embryo Development Proximal/distal Pattern Formation Embryonic Skeletal System Morphogenesis Regulation Of Cell Cycle Multicellular Organismal Development Negative Regulation Of Cell Cycle Developmental Process Skeletal System Morphogenesis Organ Morphogenesis Regulation Of Cell Cycle Process Embryonic Limb Morphogenesis Embryonic Skeletal System Development Regulation Of Metabolic Process Limb Morphogenesis Skeletal System Development Metabolic Process Chromatin Modification Limb Development Organ Development System Development Anatomical Structure Development Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Cell Cycle Phase Transition Positive Regulation Of Transcription, DNA-templated
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