GTF2I and SNRPN

Number of citations of the paper that reports this interaction (PMID 18662664)
5

Data Source:
BioGRID (pull down)

		GTF2I	SNRPN
Gene Name		general transcription factor IIi	small nuclear ribonucleoprotein polypeptide N
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane Cell Projection Neuronal Cell Body	Spliceosomal Complex U1 SnRNP U2 SnRNP Small Nuclear Ribonucleoprotein Complex
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Mitogen-activated Protein Kinase Binding	RNA Binding Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Transition Between Slow And Fast Fiber Negative Regulation Of Angiogenesis Negative Regulation Of Cytosolic Calcium Ion Concentration	RNA Splicing Response To Hormone
Pathways
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661) Pulmonary function ( 17903307)
Protein-Protein Interactions		35 interactors: AP2B1 AP4S1 ATF6 BCL2L11 BTK C4BPA CALM1 DPY30 GCC1 HDAC3 JAK2 LSM8 MAP3K3 MAPK12 MAPK3 MTUS2 MYC NFKB2 PIAS2 POU2AF1 PRKG1 PRRX1 SLU7 SMAD2 SNRPN SRC SRF STAT1 STAT3 TAB2 TRAF6 USF1 YY1 ZBTB17 ZMYM3	13 interactors: ARL4D CTBP1 FBL GAR1 GEMIN2 GTF2I KEAP1 LRIF1 MAFG RBFOX1 SH3GL3 SNRPD3 TP53
Entrez ID		2969	6638
HPRD ID		03399	01653
Ensembl ID		ENSG00000077809	ENSG00000128739
Uniprot IDs		A8K9W7 P78347 Q499G6 Q86U51	P63162
PDB IDs		2D9B 2DN4 2ED2 2EJE
Enriched GO Terms of Interacting Partners?		Response To Organic Substance Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Cellular Metabolic Process Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Positive Regulation Of Metabolic Process Response To Stress Positive Regulation Of Gene Expression Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Transcription, DNA-templated Cellular Response To Organic Substance Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Growth Factor Stimulus Response To Growth Factor Positive Regulation Of Protein Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Stress RNA Metabolic Process Intracellular Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription, DNA-templated Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Gene Expression Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Response To Stimulus Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Regulation Of Gene Expression Cellular Response To Stimulus Positive Regulation Of Protein Phosphorylation Growth Hormone Receptor Signaling Pathway Regulation Of Innate Immune Response Cellular Response To Growth Hormone Stimulus MyD88-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Transferase Activity Cell Communication Multicellular Organismal Development Toll-like Receptor 4 Signaling Pathway Regulation Of Immune System Process	RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Gene Expression Ribonucleoprotein Complex Biogenesis Positive Regulation Of Histone Deacetylation Positive Regulation Of Protein Deacetylation Transcription, DNA-templated NcRNA Metabolic Process RNA Biosynthetic Process Regulation Of Histone Deacetylation Spliceosomal SnRNP Assembly Regulation Of Epidermal Cell Differentiation Regulation Of Protein Deacetylation Regulation Of Epidermis Development Histone Glutamine Methylation Negative Regulation Of Transcription From RNA Polymerase II Promoter By Histone Modification Positive Regulation Of Histone Modification RNA Splicing Transcription From RNA Polymerase II Promoter Negative Regulation Of Macromitophagy Transition Between Slow And Fast Fiber Oligodendrocyte Apoptotic Process Peptidyl-glutamine Methylation Cellular Macromolecule Biosynthetic Process MRNA Processing Macromolecule Biosynthetic Process Negative Regulation Of Helicase Activity RRNA Processing Regulation Of Histone Modification SnoRNA Metabolic Process Proteasomal Ubiquitin-independent Protein Catabolic Process RRNA Metabolic Process In Utero Embryonic Development Cellular Metabolic Process Regulation Of Epithelial Cell Differentiation MRNA Metabolic Process Positive Regulation Of Cell Aging Positive Regulation Of Thymocyte Apoptotic Process RNA Processing Mitochondrial DNA Repair Ribonucleoprotein Complex Assembly Regulation Of Mitochondrion Degradation T Cell Proliferation Involved In Immune Response B Cell Lineage Commitment Glial Cell Apoptotic Process Ribosome Biogenesis
Tagcloud ?		74146970t ab aggressive assessment bap1 carcinomas cdkn2a classification complement cyld delta facilitate indolent isoforms missense mutation next notably pbrm1 rarely recurrent sequencing stimulate subtype subtypes tets thymic thymomas tp53	allelic biallelic blastocyst blastomere blastomeres determines discounting elucidation establishment extension f1 germ h19 igf2 igf2r imprinted imprinting manifest modes monoallelic possibility postimplantation pregastrulation preimplantation primer raises reciprocal uniform utilizing
Tagcloud (Difference) ?		74146970t ab aggressive assessment bap1 carcinomas cdkn2a classification complement cyld delta facilitate indolent isoforms missense mutation next notably pbrm1 rarely recurrent sequencing stimulate subtype subtypes tets thymic thymomas tp53	allelic biallelic blastocyst blastomere blastomeres determines discounting elucidation establishment extension f1 germ h19 igf2 igf2r imprinted imprinting manifest modes monoallelic possibility postimplantation pregastrulation preimplantation primer raises reciprocal uniform utilizing
Tagcloud (Intersection) ?