SNRPN and GEMIN2

Number of citations of the paper that reports this interaction (PMID 18984161)
35

Data Source:
BioGRID (pull down)

		SNRPN	GEMIN2
Gene Name		small nuclear ribonucleoprotein polypeptide N	gem (nuclear organelle) associated protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Spliceosomal Complex U1 SnRNP U2 SnRNP Small Nuclear Ribonucleoprotein Complex	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytoplasm Cytosol SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies
	Molecular Function	RNA Binding Protein Binding	Protein Binding
	Biological Process	RNA Splicing Response To Hormone	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions Spliceosomal SnRNP Assembly MRNA Processing RNA Splicing Gene Expression NcRNA Metabolic Process
Pathways			snRNP Assembly Metabolism of non-coding RNA
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Pulmonary function ( 17903307)
Protein-Protein Interactions		13 interactors: ARL4D CTBP1 FBL GAR1 GEMIN2 GTF2I KEAP1 LRIF1 MAFG RBFOX1 SH3GL3 SNRPD3 TP53	21 interactors: DDX20 DHX9 GEMIN5 IKBKG RN7SL1 RNU1-1 RNU2-1 SMN1 SMN2 SNRNP70 SNRPD1 SNRPD2 SNRPD3 SNRPN SRSF1 SRSF2 SRSF3 SRSF4 STXBP2 STXBP3 U2AF2
Entrez ID		6638	8487
HPRD ID		01653	03999
Ensembl ID		ENSG00000128739	ENSG00000092208
Uniprot IDs		P63162	O14893
PDB IDs			2LEH 3S6N
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Gene Expression Ribonucleoprotein Complex Biogenesis Positive Regulation Of Histone Deacetylation Positive Regulation Of Protein Deacetylation Transcription, DNA-templated NcRNA Metabolic Process RNA Biosynthetic Process Regulation Of Histone Deacetylation Spliceosomal SnRNP Assembly Regulation Of Epidermal Cell Differentiation Regulation Of Protein Deacetylation Regulation Of Epidermis Development Histone Glutamine Methylation Negative Regulation Of Transcription From RNA Polymerase II Promoter By Histone Modification Positive Regulation Of Histone Modification RNA Splicing Transcription From RNA Polymerase II Promoter Negative Regulation Of Macromitophagy Transition Between Slow And Fast Fiber Oligodendrocyte Apoptotic Process Peptidyl-glutamine Methylation Cellular Macromolecule Biosynthetic Process MRNA Processing Macromolecule Biosynthetic Process Negative Regulation Of Helicase Activity RRNA Processing Regulation Of Histone Modification SnoRNA Metabolic Process Proteasomal Ubiquitin-independent Protein Catabolic Process RRNA Metabolic Process In Utero Embryonic Development Cellular Metabolic Process Regulation Of Epithelial Cell Differentiation MRNA Metabolic Process Positive Regulation Of Cell Aging Positive Regulation Of Thymocyte Apoptotic Process RNA Processing Mitochondrial DNA Repair Ribonucleoprotein Complex Assembly Regulation Of Mitochondrion Degradation T Cell Proliferation Involved In Immune Response B Cell Lineage Commitment Glial Cell Apoptotic Process Ribosome Biogenesis	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process Spliceosomal SnRNP Assembly Termination Of RNA Polymerase II Transcription Ribonucleoprotein Complex Assembly RNA Metabolic Process Gene Expression DNA-templated Transcription, Termination MRNA 3'-end Processing Ribonucleoprotein Complex Biogenesis RNA 3'-end Processing Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Spliceosomal Complex Assembly MRNA Export From Nucleus Cellular Nitrogen Compound Metabolic Process RNA Export From Nucleus Nitrogen Compound Metabolic Process Cellular Macromolecular Complex Assembly Nuclear Export MRNA Transport NcRNA Metabolic Process RNA Transport RNA Localization Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing Nucleocytoplasmic Transport Nuclear Transport Cellular Component Assembly Neutrophil Degranulation Neutrophil Activation Involved In Immune Response Transcription From RNA Polymerase II Promoter Establishment Of Localization In Cell Cellular Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Neutrophil Mediated Immunity Neutrophil Activation Cytoplasmic Transport Cellular Localization Positive Regulation Of RNA Splicing Leukocyte Degranulation Regulation Of MRNA Stability Regulated Secretory Pathway
Tagcloud ?		allelic biallelic blastocyst blastomere blastomeres determines discounting elucidation establishment extension f1 germ h19 igf2 igf2r imprinted imprinting manifest modes monoallelic possibility postimplantation pregastrulation preimplantation primer raises reciprocal uniform utilizing	associates atrophy characterised efficiently epitope epitopes exists explain hela immunised immuno inherited library mab mabs mansma1 mansma12 mansma3 masked motor multimeric muscular phage precipitated precise proline smn spliceosome vigorous
Tagcloud (Difference) ?		allelic biallelic blastocyst blastomere blastomeres determines discounting elucidation establishment extension f1 germ h19 igf2 igf2r imprinted imprinting manifest modes monoallelic possibility postimplantation pregastrulation preimplantation primer raises reciprocal uniform utilizing	associates atrophy characterised efficiently epitope epitopes exists explain hela immunised immuno inherited library mab mabs mansma1 mansma12 mansma3 masked motor multimeric muscular phage precipitated precise proline smn spliceosome vigorous
Tagcloud (Intersection) ?