SNRPN and SH3GL3

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		SNRPN	SH3GL3
Gene Name		small nuclear ribonucleoprotein polypeptide N	SH3-domain GRB2-like 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Spliceosomal Complex U1 SnRNP U2 SnRNP Small Nuclear Ribonucleoprotein Complex	Early Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	RNA Binding Protein Binding	Protein Binding Lipid Binding Identical Protein Binding
	Biological Process	RNA Splicing Response To Hormone	Endocytosis Signal Transduction Central Nervous System Development
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Pulmonary function ( 17903307)	Height ( 18391950 18391951 20397748)
Protein-Protein Interactions		13 interactors: ARL4D CTBP1 FBL GAR1 GEMIN2 GTF2I KEAP1 LRIF1 MAFG RBFOX1 SH3GL3 SNRPD3 TP53	44 interactors: ADRB1 AES ARHGDIA ARHGEF6 ATXN2 C11orf68 C4orf17 CALCOCO1 CBLC CD101 CRIP1 DNM1 DPPA4 DPYSL4 EGFL6 EMD FAM173A FASLG GABBR2 HTT LRRK2 NDUFB9 PDCD6IP PIAS4 PTPRO QTRT1 RBM48 RER1 RPL35A SEPT8 SH3D19 SH3GL1 SH3GL2 SH3KBP1 SHC3 SNRPN SNX24 SYNJ1 TERF1 TNNT1 TOE1 VIM WASL WDR33
Entrez ID		6638	6457
HPRD ID		01653	04528
Ensembl ID		ENSG00000128739	ENSG00000140600
Uniprot IDs		P63162	Q99963
PDB IDs			2EW3 2Z0V
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Gene Expression Ribonucleoprotein Complex Biogenesis Positive Regulation Of Histone Deacetylation Positive Regulation Of Protein Deacetylation Transcription, DNA-templated NcRNA Metabolic Process RNA Biosynthetic Process Regulation Of Histone Deacetylation Spliceosomal SnRNP Assembly Regulation Of Epidermal Cell Differentiation Regulation Of Protein Deacetylation Regulation Of Epidermis Development Histone Glutamine Methylation Negative Regulation Of Transcription From RNA Polymerase II Promoter By Histone Modification Positive Regulation Of Histone Modification RNA Splicing Transcription From RNA Polymerase II Promoter Negative Regulation Of Macromitophagy Transition Between Slow And Fast Fiber Oligodendrocyte Apoptotic Process Peptidyl-glutamine Methylation Cellular Macromolecule Biosynthetic Process MRNA Processing Macromolecule Biosynthetic Process Negative Regulation Of Helicase Activity RRNA Processing Regulation Of Histone Modification SnoRNA Metabolic Process Proteasomal Ubiquitin-independent Protein Catabolic Process RRNA Metabolic Process In Utero Embryonic Development Cellular Metabolic Process Regulation Of Epithelial Cell Differentiation MRNA Metabolic Process Positive Regulation Of Cell Aging Positive Regulation Of Thymocyte Apoptotic Process RNA Processing Mitochondrial DNA Repair Ribonucleoprotein Complex Assembly Regulation Of Mitochondrion Degradation T Cell Proliferation Involved In Immune Response B Cell Lineage Commitment Glial Cell Apoptotic Process Ribosome Biogenesis	Cell Surface Receptor Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Signaling Regulation Of ERBB Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cell-cell Signaling Signal Transduction Vesicle-mediated Transport Cell Communication Movement Of Cell Or Subcellular Component Regulation Of Vesicle-mediated Transport Response To Stimulus Cellular Response To Stimulus Cell Death Death Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Membrane Organization Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuron Projection Morphogenesis Negative Regulation Of ERBB Signaling Pathway Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Developmental Process System Development Neuron Development Apoptotic Process Cellular Process Generation Of Neurons Actin Filament-based Movement Multicellular Organismal Development Nervous System Development Programmed Cell Death Regulation Of Signaling Neurogenesis Regulation Of Endocytosis Regulation Of Signal Transduction Negative Regulation Of Neuron Differentiation Neuron Projection Development Establishment Of Vesicle Localization Synaptic Transmission Positive Regulation Of Apoptotic Process Cell Projection Morphogenesis Neuron Differentiation Vesicle Localization Response To Growth Factor Axon Guidance Neurotrophin TRK Receptor Signaling Pathway Cell Part Morphogenesis
Tagcloud ?		allelic biallelic blastocyst blastomere blastomeres determines discounting elucidation establishment extension f1 germ h19 igf2 igf2r imprinted imprinting manifest modes monoallelic possibility postimplantation pregastrulation preimplantation primer raises reciprocal uniform utilizing	85k aorta cbl cin85 circulation circulatory cooperation da diameters dorsal endocytosis exerted impairing interacting lumen lumens morpholino morpholinos partner phosphatidylinositol shrinkage shrunken specification stereotyped studying unaffected vasculature zebrafish
Tagcloud (Difference) ?		allelic biallelic blastocyst blastomere blastomeres determines discounting elucidation establishment extension f1 germ h19 igf2 igf2r imprinted imprinting manifest modes monoallelic possibility postimplantation pregastrulation preimplantation primer raises reciprocal uniform utilizing	85k aorta cbl cin85 circulation circulatory cooperation da diameters dorsal endocytosis exerted impairing interacting lumen lumens morpholino morpholinos partner phosphatidylinositol shrinkage shrunken specification stereotyped studying unaffected vasculature zebrafish
Tagcloud (Intersection) ?