GTF2I and AP4S1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GTF2I	AP4S1
Gene Name		general transcription factor IIi	adaptor-related protein complex 4, sigma 1 subunit
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane Cell Projection Neuronal Cell Body	Golgi Apparatus Coated Pit
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Mitogen-activated Protein Kinase Binding	Transporter Activity Protein Transporter Activity
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Transition Between Slow And Fast Fiber Negative Regulation Of Angiogenesis Negative Regulation Of Cytosolic Calcium Ion Concentration	Protein Transport
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		35 interactors: AP2B1 AP4S1 ATF6 BCL2L11 BTK C4BPA CALM1 DPY30 GCC1 HDAC3 JAK2 LSM8 MAP3K3 MAPK12 MAPK3 MTUS2 MYC NFKB2 PIAS2 POU2AF1 PRKG1 PRRX1 SLU7 SMAD2 SNRPN SRC SRF STAT1 STAT3 TAB2 TRAF6 USF1 YY1 ZBTB17 ZMYM3	6 interactors: AFP AP4E1 APP GRB2 GTF2I TEAD3
Entrez ID		2969	11154
HPRD ID		03399	06257
Ensembl ID		ENSG00000077809	ENSG00000100478
Uniprot IDs		A8K9W7 P78347 Q499G6 Q86U51	Q9Y587
PDB IDs		2D9B 2DN4 2ED2 2EJE
Enriched GO Terms of Interacting Partners?		Response To Organic Substance Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Cellular Metabolic Process Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Positive Regulation Of Metabolic Process Response To Stress Positive Regulation Of Gene Expression Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Transcription, DNA-templated Cellular Response To Organic Substance Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Growth Factor Stimulus Response To Growth Factor Positive Regulation Of Protein Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Stress RNA Metabolic Process Intracellular Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription, DNA-templated Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Gene Expression Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Response To Stimulus Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Regulation Of Gene Expression Cellular Response To Stimulus Positive Regulation Of Protein Phosphorylation Growth Hormone Receptor Signaling Pathway Regulation Of Innate Immune Response Cellular Response To Growth Hormone Stimulus MyD88-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Transferase Activity Cell Communication Multicellular Organismal Development Toll-like Receptor 4 Signaling Pathway Regulation Of Immune System Process	Reproductive Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Transition Between Slow And Fast Fiber Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Transcription Initiation From RNA Polymerase II Promoter Platelet Activation Collateral Sprouting Axon Midline Choice Point Recognition DNA-templated Transcription, Initiation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Steroid Metabolic Process Positive Regulation Of Stem Cell Maintenance Regulation Of Skeletal Muscle Adaptation Cellular Calcium Ion Homeostasis Negative Regulation Of Cytosolic Calcium Ion Concentration Neuron Remodeling Calcium Ion Homeostasis Branching Involved In Labyrinthine Layer Morphogenesis Signal Transduction Ovulation From Ovarian Follicle Signaling Axon Guidance Vesicle-mediated Transport Cell Communication Cellular Metal Ion Homeostasis Blood Coagulation Cellular Copper Ion Homeostasis Hemostasis Cellular Cation Homeostasis Response To Radiation Cellular Ion Homeostasis Progesterone Metabolic Process Ovulation Metal Ion Homeostasis Labyrinthine Layer Morphogenesis Copper Ion Homeostasis Suckling Behavior
Tagcloud ?		74146970t ab aggressive assessment bap1 carcinomas cdkn2a classification complement cyld delta facilitate indolent isoforms missense mutation next notably pbrm1 rarely recurrent sequencing stimulate subtype subtypes tets thymic thymomas tp53
Tagcloud (Difference) ?		74146970t ab aggressive assessment bap1 carcinomas cdkn2a classification complement cyld delta facilitate indolent isoforms missense mutation next notably pbrm1 rarely recurrent sequencing stimulate subtype subtypes tets thymic thymomas tp53
Tagcloud (Intersection) ?