BRD7 and LAMA4

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		BRD7	LAMA4
Gene Name		bromodomain containing 7	laminin, alpha 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Extracellular Region Basement Membrane Basal Lamina Laminin-1 Complex Extracellular Matrix Extracellular Vesicular Exosome
	Molecular Function	P53 Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Histone Binding Transcription Regulatory Region DNA Binding Lysine-acetylated Histone Binding	Receptor Binding Extracellular Matrix Structural Constituent Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Cell Cycle Negative Regulation Of Cell Proliferation Wnt Signaling Pathway Positive Regulation Of Histone Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Cell Adhesion Regulation Of Cell Adhesion Extracellular Matrix Organization Regulation Of Cell Migration Regulation Of Embryonic Development
Pathways			Laminin interactions ECM proteoglycans Non-integrin membrane-ECM interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: AGR2 BARD1 BHLHE40 BRD3 BTBD2 DVL1 FTH1 HAP1 HIST1H2AL HIST2H2BE HIST2H3C HIST3H3 HIST4H4 HNRNPUL1 IRF2 LAMA4 LRIF1 NEFL PAFAH1B3 PCBD1 PSMD11 PTPN13 RBFOX2 RIF1 RPLP1 SERPINB9 TRIM24	15 interactors: APC ATF7IP BRD7 COPS6 EEF1A1 GAPDH LRIF1 MED31 PTN RTN4 TP53 TUBB2A UBR1 UNC119 ZHX1
Entrez ID		29117	3910
HPRD ID		12531	02532
Ensembl ID		ENSG00000166164	ENSG00000112769
Uniprot IDs		Q9NPI1	Q16363 Q5D044
PDB IDs		2I7K
Enriched GO Terms of Interacting Partners?		Gene Expression Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Retrograde Axon Cargo Transport Transcription, DNA-templated Telomere Maintenance DNA Methylation On Cytosine DNA Modification Chromatin Silencing At RDNA Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Neuromuscular Process Negative Regulation Of Biosynthetic Process Anterograde Axon Cargo Transport Cellular Response To Estrogen Stimulus Chromatin Silencing Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Regulation Of Metabolic Process Axon Cargo Transport Regulation Of Gene Expression, Epigenetic Positive Regulation Of Protein Catabolic Process DNA Methylation Demethylation Mucus Secretion Intracellular Sequestering Of Iron Ion Negative Regulation Of MRNA 3'-end Processing Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Homeostatic Process Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Cell Projection Organization Neuromuscular Process Controlling Balance Convergent Extension Involved In Neural Plate Elongation	Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Fibroblast Proliferation Transcription, DNA-templated Regulation Of Chromosome Organization Mitotic Cytokinesis RNA Biosynthetic Process Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Negative Regulation Of Cell Proliferation Negative Regulation Of Clathrin-mediated Endocytosis Peptidyl-cysteine S-trans-nitrosylation Regulation Of Cellular Component Organization Neuron Death T Cell Differentiation In Thymus Positive Regulation Of Histone Modification Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Regulation Of Protein Complex Assembly Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Macromitophagy Cellular Response To Leucine Negative Regulation Of Caveolin-mediated Endocytosis Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Oligodendrocyte Apoptotic Process Regulation Of Cell Proliferation Regulation Of Fibroblast Proliferation Regulation Of Cellular Amino Acid Metabolic Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle RNA Metabolic Process Positive Regulation Of Organelle Organization Regulation Of Branching Morphogenesis Of A Nerve Cytokinesis, Completion Of Separation Negative Regulation Of Helicase Activity Cytokinesis Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Apoptotic Process Negative Regulation Of Odontogenesis Regulation Of Histone Modification Gene Expression Positive Regulation Of Cell Division Programmed Cell Death Peptidyl-cysteine S-nitrosylation Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Protein Complex Assembly
Tagcloud ?		aza clinically cofactor dc demethylating disturbing ectopic endogenous finding glioma gliomas hypermethylation implicated inactivated inactivation intracranial lrrc4 magnetic microrna mir negatively pathological researches resonance restoration silencing transcriptional transplanted verified	angpt1 angpt2 ca9 cdh5 cdkn2a ednra erbb1 gadd45b glut1 hif2a hippel inherited irs1 lindau looked microadenomas neuroendocrine nineteen ocln pannet pdgfb predisposing rps6kb1 vegfa vegfr1 vegfr2 vhl vim von
Tagcloud (Difference) ?		aza clinically cofactor dc demethylating disturbing ectopic endogenous finding glioma gliomas hypermethylation implicated inactivated inactivation intracranial lrrc4 magnetic microrna mir negatively pathological researches resonance restoration silencing transcriptional transplanted verified	angpt1 angpt2 ca9 cdh5 cdkn2a ednra erbb1 gadd45b glut1 hif2a hippel inherited irs1 lindau looked microadenomas neuroendocrine nineteen ocln pannet pdgfb predisposing rps6kb1 vegfa vegfr1 vegfr2 vhl vim von
Tagcloud (Intersection) ?