LAMA4

Name	laminin subunit alpha 4
Structure	No pdb structure
Novel Interactors	2 novel interactors: HDAC2 PACS1
Interactors	17 interactors: APC ATF7IP BRD7 COPS6 EEF1A1 FHL1 GAPDH LRIF1 MED31 PTN RTN4 RTP2 TP53 TUBB2A UBR1 UNC119 ZHX1
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Extracellular Matrix Extracellular Exosome
	Molecular Function	Signaling Receptor Binding Extracellular Matrix Structural Constituent Protein Binding
	Biological Process	Cell Adhesion Regulation Of Cell Adhesion Regulation Of Cell Migration Regulation Of Embryonic Development Negative Regulation Of Cold-induced Thermogenesis
Pathways	Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans MET activates PTK2 signaling Attachment of bacteria to epithelial cells Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC) Developmental Lineage of Pancreatic Ductal Cells
GWAS	A body shape index ( 34021172 ) Bipolar disorder ( 31043756 ) Metabolite levels ( 23823483 ) Waist circumference adjusted for body mass index ( 34021172 ) Waist-hip index ( 34021172 ) Waist-to-hip ratio adjusted for BMI ( 34021172 )
Entrez ID	3910
HPRD ID	02532
Ensembl ID	ENSG00000112769
Uniprot IDs	A0A0A0MTC7 Q16363 Q5D044
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Epigenetic Regulation Of Gene Expression Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Hepatocyte Proliferation Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Phase Transition Regulation Of Protein Metabolic Process Regulation Of Hepatocyte Proliferation Negative Regulation Of Neuroblast Proliferation Regulation Of Gliogenesis Leukocyte Migration Involved In Inflammatory Response Negative Regulation Of Cell Cycle Process Positive Regulation Of Oligodendrocyte Differentiation Regulation Of Primary Metabolic Process Disordered Domain Specific Binding Negative Regulation Of Neural Precursor Cell Proliferation Molecular Function Activator Activity Nuclear Matrix Negative Regulation Of Neurogenesis Regulation Of Mitotic Cell Cycle Phase Transition Heterochromatin Formation Negative Regulation Of Nervous System Development Negative Regulation Of Cell Cycle Chromatin Remodeling Regulation Of Neurogenesis Negative Regulation Of Fibroblast Proliferation Negative Regulation Of Catalytic Activity Negative Regulation Of Cellular Component Organization Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Cell Growth Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Glial Cell Differentiation Regulation Of Oligodendrocyte Differentiation Positive Regulation Of Male Mating Behavior Dendrite Development Regulation Of Neuroblast Proliferation Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition Negative Regulation Of Vasculogenesis Positive Regulation Of ERBB3 Signaling Pathway Cell Adhesion Involved In Sprouting Angiogenesis Regulation Of Macromolecule Metabolic Process Regulation Of Nervous System Development Regulation Of Cell Cycle Phase Transition Negative Regulation Of Metabolic Process Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Gene Expression, Epigenetic