LAMA4 and TUBB2A

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)

		LAMA4	TUBB2A
Gene Name		laminin, alpha 4	tubulin, beta 2A class IIa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Basement Membrane Basal Lamina Laminin-1 Complex Extracellular Matrix Extracellular Vesicular Exosome	Nucleus Cytoplasm Microtubule Vesicle Extracellular Vesicular Exosome
	Molecular Function	Receptor Binding Extracellular Matrix Structural Constituent Protein Binding	GTPase Activity Structural Constituent Of Cytoskeleton GTP Binding
	Biological Process	Cell Adhesion Regulation Of Cell Adhesion Extracellular Matrix Organization Regulation Of Cell Migration Regulation Of Embryonic Development	Protein Folding Microtubule-based Process Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding Protein Polymerization Transmembrane Transport
Pathways		Laminin interactions ECM proteoglycans Non-integrin membrane-ECM interactions	Transport of connexons to the plasma membrane Mitotic Prometaphase Organelle biogenesis and maintenance Axon guidance Hedgehog 'off' state Separation of Sister Chromatids Translocation of GLUT4 to the plasma membrane G2/M Transition L1CAM interactions Mitotic Anaphase Recycling pathway of L1 Recruitment of NuMA to mitotic centrosomes Formation of tubulin folding intermediates by CCT/TriC Intraflagellar transport M Phase Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Post-chaperonin tubulin folding pathway Gap junction trafficking and regulation MHC class II antigen presentation Recruitment of mitotic centrosome proteins and complexes Orphan transporters Protein folding Gap junction assembly Gap junction trafficking Kinesins Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Assembly of the primary cilium Factors involved in megakaryocyte development and platelet production Cell Cycle, Mitotic Resolution of Sister Chromatid Cohesion Chaperonin-mediated protein folding Signaling by Hedgehog Centrosome maturation Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: APC ATF7IP BRD7 COPS6 EEF1A1 GAPDH LRIF1 MED31 PTN RTN4 TP53 TUBB2A UBR1 UNC119 ZHX1	24 interactors: ACD ARL15 CHGB DISC1 HDAC6 HGS HMMR LAMA4 PAFAH1B3 POT1 PSMD11 PTPRS RABAC1 RIC8A RPA2 RPLP1 SAT1 SDC3 SERPINB9 TERF1 TK1 TNIK TPT1 UPF2
Entrez ID		3910	7280
HPRD ID		02532
Ensembl ID		ENSG00000112769	ENSG00000137267
Uniprot IDs		Q16363 Q5D044	Q13885
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Fibroblast Proliferation Transcription, DNA-templated Regulation Of Chromosome Organization Mitotic Cytokinesis RNA Biosynthetic Process Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Negative Regulation Of Cell Proliferation Negative Regulation Of Clathrin-mediated Endocytosis Peptidyl-cysteine S-trans-nitrosylation Regulation Of Cellular Component Organization Neuron Death T Cell Differentiation In Thymus Positive Regulation Of Histone Modification Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Regulation Of Protein Complex Assembly Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Macromitophagy Cellular Response To Leucine Negative Regulation Of Caveolin-mediated Endocytosis Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Oligodendrocyte Apoptotic Process Regulation Of Cell Proliferation Regulation Of Fibroblast Proliferation Regulation Of Cellular Amino Acid Metabolic Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle RNA Metabolic Process Positive Regulation Of Organelle Organization Regulation Of Branching Morphogenesis Of A Nerve Cytokinesis, Completion Of Separation Negative Regulation Of Helicase Activity Cytokinesis Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Apoptotic Process Negative Regulation Of Odontogenesis Regulation Of Histone Modification Gene Expression Positive Regulation Of Cell Division Programmed Cell Death Peptidyl-cysteine S-nitrosylation Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Protein Complex Assembly	Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomerase Activity Telomere Maintenance Regulation Of Telomere Maintenance Telomere Maintenance Via Telomere Lengthening Telomere Assembly Regulation Of DNA Biosynthetic Process Telomere Capping Negative Regulation Of DNA Replication Catabolic Process Positive Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomerase Activity Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Cellular Protein Localization Positive Regulation Of DNA Biosynthetic Process Cellular Component Assembly RNA-dependent DNA Replication Regulation Of DNA Replication Negative Regulation Of DNA Biosynthetic Process Response To Stimulus Developmental Process Regulation Of Proteolysis Negative Regulation Of Mitotic Cell Cycle Phase Transition Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Protein Catabolic Process Mitotic Cell Cycle Checkpoint Glycosaminoglycan Metabolic Process Negative Regulation Of Catalytic Activity Regulation Of Catalytic Activity Regulation Of Chromosome Organization Cellular Macromolecule Catabolic Process Cellular Localization Pathogenesis Cell-cell Adhesion Involved In Gastrulation Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation Fetal Process Involved In Parturition Hsp90 Deacetylation Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Homeostatic Process Protein Localization Intracellular Protein Transport Regulation Of Cell Cycle Phase Transition
Tagcloud ?		angpt1 angpt2 ca9 cdh5 cdkn2a ednra erbb1 gadd45b glut1 hif2a hippel inherited irs1 lindau looked microadenomas neuroendocrine nineteen ocln pannet pdgfb predisposing rps6kb1 vegfa vegfr1 vegfr2 vhl vim von
Tagcloud (Difference) ?		angpt1 angpt2 ca9 cdh5 cdkn2a ednra erbb1 gadd45b glut1 hif2a hippel inherited irs1 lindau looked microadenomas neuroendocrine nineteen ocln pannet pdgfb predisposing rps6kb1 vegfa vegfr1 vegfr2 vhl vim von
Tagcloud (Intersection) ?