BRD7 and BRD3

Number of citations of the paper that reports this interaction (PubMedID 12600283)
0

Data Source:
HPRD (two hybrid)

		BRD7	BRD3
Description		bromodomain containing 7	bromodomain containing 3
Image
GO Annotations	Cellular Component	Kinetochore Chromatin Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Nuclear Matrix RSC-type Complex	Chromatin Nucleus Chromosome
	Molecular Function	Transcription Cis-regulatory Region Binding P53 Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Histone Binding Histone H3K14ac Reader Activity Histone Reader Activity	Chromatin Binding Protein Serine/threonine Kinase Activity Protein Binding Protein-macromolecule Adaptor Activity Histone Binding Histone H3K9me2/3 Reader Activity LncRNA Binding Histone H3K18cr Reader Activity Histone H3K9cr Reader Activity Histone H3K27cr Reader Activity Histone Reader Activity Molecular Condensate Scaffold Activity
	Biological Process	Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Regulation Of Mitotic Cell Cycle Wnt Signaling Pathway Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of T Cell Differentiation Positive Regulation Of Cell Differentiation Positive Regulation Of Myoblast Differentiation Transcription Initiation-coupled Chromatin Remodeling Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Regulation Of G0 To G1 Transition Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Double-strand Break Repair Regulation Of Nucleotide-excision Repair	Chromatin Organization Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Endodermal Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Protein Localization To Chromatin
Pathways		Regulation of TP53 Activity through Acetylation Formation of the polybromo-BAF (pBAF) complex
Drugs
Diseases
GWAS		Allergic sensitization ( 30013184) Epilepsy ( 30531953) Liver enzyme levels (alanine transaminase) ( 24124411) Medication use (thyroid preparations) ( 31015401)	Alanine aminotransferase levels ( 34315874) Alcohol consumption (drinks per week) ( 30643258) Apolipoprotein A1 levels ( 32203549) Aspartate aminotransferase levels ( 34315874) Brain-derived neurotrophic factor levels ( 33345186) Central corneal thickness ( 31798171 29760442) Cerebrospinal fluid t-tau levels in normal cognition ( 29274321) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Eosinophil count ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252 32888494) Estimated glomerular filtration rate ( 31152163) Granulocyte percentage of myeloid white cells ( 27863252) HDL cholesterol levels ( 32203549) Immature fraction of reticulocytes ( 32888494) Intraocular pressure ( 29617998 30591961) Lymphocyte count ( 32888494) Mean platelet volume ( 27863252 32888494) Mosquito bite size ( 28199695) Neutrophil count ( 27863252 32888494) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 32888494 27863252) Platelet count ( 32888494 22139419) Platelet distribution width ( 27863252) Red cell distribution width ( 28957414 32888494 27863252) Sum basophil neutrophil counts ( 27863252) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		30 interacting genes: AGR2 BARD1 BHLHE40 BRD3 BTBD2 DVL1 FTH1 H2AC16 H2BC21 H3-3A H3-4 H3C14 H4C16 HAP1 HNRNPUL1 IRF2 LAMA4 LRIF1 MX1 NEFL PAFAH1B3 PARP1 PCBD1 PLEKHF2 PSMD11 PTPN13 RIF1 RPLP1 SERPINB9 TRIM24	6 interacting genes: APP BRD7 MAP1LC3B MYC SPOP SPP1
Entrez ID		29117	8019
HPRD ID		12531	03327
Ensembl ID		ENSG00000166164	ENSG00000169925
Uniprot IDs		A0AA34QVS2 Q9NPI1	Q15059
PDB IDs		2I7K 5MQ1 6PPA 6V0Q 6V16 6V17 6V1E 6V1F 6V1H 7VDV 7Y8R	2E7N 2NXB 2OO1 2YW5 3S91 3S92 5A7C 5HFR 5HJC 6BGG 6BGH 6I41 6I5P 6I68 6I7A 6QJU 6U4A 6ULP 7JMY 7JQ8 7JYN 7JYZ 7L72 7L9L 7LAY 7LAZ 7LB4 7LBT 7R8R 7RJK 7RJL 7RJM 7RJN 7S3P 7TO7 7TO8 7TO9 7TOA 7UG5 8B5A 8CV5
Enriched GO Terms of Interacting Partners?		Chromatin Remodeling Chromatin Organization Protein Heterodimerization Activity Structural Constituent Of Chromatin Nucleosome Chromosome Chromosome, Telomeric Region Nucleosome Assembly Nucleosome Organization Protein-DNA Complex Assembly Nucleus Barr Body Telomere Organization Negative Regulation Of Metabolic Process Protein Localization To Chromatin Heterochromatin Formation Subtelomeric Heterochromatin Formation Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Nucleoplasm Chromatin Cellular Response To Estrogen Stimulus Extracellular Exosome Retrograde Axonal Transport Protein Binding Protein Localization To Chromosome NAD+-histone H3S10 Serine ADP-ribosyltransferase Activity NAD+-histone H2BS6 Serine ADP-ribosyltransferase Activity NAD+-histone H2BE35 Glutamate ADP-ribosyltransferase Activity NAD+-protein-histidine ADP-ribosyltransferase Activity NAD+-protein-tyrosine ADP-ribosyltransferase Activity Negative Regulation Of MRNA 3'-end Processing Epigenetic Regulation Of Gene Expression Histone H3K9cr Reader Activity Histone H3K27cr Reader Activity Histone H3K18cr Reader Activity Histone H3K23ac Reader Activity Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Neurotrophin Production Positive Regulation Of ERBB Signaling Pathway Chromosome, Telomeric Repeat Region Regulation Of Developmental Process Growth Cone Response To Mineralocorticoid	Positive Regulation Of Gene Expression, Epigenetic Amyloid-beta Complex Growth Cone Lamellipodium Epigenetic Regulation Of Gene Expression Regulation Of Response To Calcium Ion Regulation Of MiRNA Transcription Perinuclear Region Of Cytoplasm Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Cellular Response To Stress Striated Muscle Cell Differentiation Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Ubiquitin Protein Ligase Binding Acinar Cell Proliferation Positive Regulation Of Acinar Cell Proliferation SCF Ubiquitin Ligase Complex Binding Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Memory T Cell Differentiation Regulation Of Cell Cycle Adult Locomotory Behavior Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding Regulation Of Cellular Component Organization PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Associative Learning Regulation Of MiRNA Metabolic Process Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Response To Peptide Response To Cytokine Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Leukocyte Activation Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization NK T Cell Proliferation Myc-Max Complex Muscle Cell Differentiation Regulation Of Acinar Cell Proliferation Positive Regulation Of Estradiol Secretion Regulation Of Estradiol Secretion Response To Nutrient Levels TSC1-TSC2 Complex Response To Norepinephrine Integrin Binding Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?