BRD7 and BRD3

Number of citations of the paper that reports this interaction (PMID 12600283)
1

Data Source:
HPRD (two hybrid)

		BRD7	BRD3
Gene Name		bromodomain containing 7	bromodomain containing 3
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus
	Molecular Function	P53 Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Histone Binding Transcription Regulatory Region DNA Binding Lysine-acetylated Histone Binding	Chromatin Binding Protein Binding Lysine-acetylated Histone Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Cell Cycle Negative Regulation Of Cell Proliferation Wnt Signaling Pathway Positive Regulation Of Histone Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification
Pathways
Drugs
Diseases
GWAS			Platelet counts ( 22139419)
Protein-Protein Interactions		27 interactors: AGR2 BARD1 BHLHE40 BRD3 BTBD2 DVL1 FTH1 HAP1 HIST1H2AL HIST2H2BE HIST2H3C HIST3H3 HIST4H4 HNRNPUL1 IRF2 LAMA4 LRIF1 NEFL PAFAH1B3 PCBD1 PSMD11 PTPN13 RBFOX2 RIF1 RPLP1 SERPINB9 TRIM24	6 interactors: APP BRD7 MAP1LC3B MYC SPP1 SRPK2
Entrez ID		29117	8019
HPRD ID		12531	03327
Ensembl ID		ENSG00000166164	ENSG00000169925
Uniprot IDs		Q9NPI1	Q15059
PDB IDs		2I7K	2E7N 2NXB 2OO1 2YW5 3S91 3S92
Enriched GO Terms of Interacting Partners?		Gene Expression Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Retrograde Axon Cargo Transport Transcription, DNA-templated Telomere Maintenance DNA Methylation On Cytosine DNA Modification Chromatin Silencing At RDNA Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Neuromuscular Process Negative Regulation Of Biosynthetic Process Anterograde Axon Cargo Transport Cellular Response To Estrogen Stimulus Chromatin Silencing Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Regulation Of Metabolic Process Axon Cargo Transport Regulation Of Gene Expression, Epigenetic Positive Regulation Of Protein Catabolic Process DNA Methylation Demethylation Mucus Secretion Intracellular Sequestering Of Iron Ion Negative Regulation Of MRNA 3'-end Processing Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Homeostatic Process Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Cell Projection Organization Neuromuscular Process Controlling Balance Convergent Extension Involved In Neural Plate Elongation	Regulation Of Cell Cycle Positive Regulation Of Gene Expression Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Nuclear Speck Organization Response To Stress Cellular Response To Stimulus Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Synaptic Growth At Neuromuscular Junction Fibroblast Apoptotic Process Notch Signaling Pathway Negative Regulation Of Cell Differentiation Positive Regulation Of Peptidase Activity Transition Metal Ion Homeostasis Collateral Sprouting In Absence Of Injury Negative Regulation Of Neuron Differentiation Regulation Of Chromosome Organization Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Monocyte Differentiation Negative Regulation Of Collateral Sprouting Axon Choice Point Recognition Positive Regulation Of Cell Proliferation Involved In Kidney Development Response To Stimulus Negative Regulation Of Axon Regeneration Positive Regulation Of Cellular Protein Metabolic Process Wnt Signaling Pathway Positive Regulation Of Cell Cycle Regulation Of Developmental Growth Negative Regulation Of Neurogenesis Positive Regulation Of Proteolysis Neuron Remodeling Positive Regulation Of Protein Metabolic Process Negative Regulation Of Cell Development Response To Light Stimulus Positive Regulation Of Transcription, DNA-templated Defense Response Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Monocyte Differentiation Regulation Of Endopeptidase Activity Regulation Of Cellular Amino Acid Metabolic Process RNA Metabolic Process Cell Communication Positive Regulation Of Bone Resorption Regulation Of Cell Proliferation Cellular Metal Ion Homeostasis
Tagcloud ?		aza clinically cofactor dc demethylating disturbing ectopic endogenous finding glioma gliomas hypermethylation implicated inactivated inactivation intracranial lrrc4 magnetic microrna mir negatively pathological researches resonance restoration silencing transcriptional transplanted verified	acquired bet breast classic degrader effort epigenomic eralpha estrogen facilitates frontline fulvestrant h3k36 jq1 lasting methyltransferase modifiers potently premenopausal recruited regulator regulators screen sirna tam tamoxifen valid whsc1 xenograft
Tagcloud (Difference) ?		aza clinically cofactor dc demethylating disturbing ectopic endogenous finding glioma gliomas hypermethylation implicated inactivated inactivation intracranial lrrc4 magnetic microrna mir negatively pathological researches resonance restoration silencing transcriptional transplanted verified	acquired bet breast classic degrader effort epigenomic eralpha estrogen facilitates frontline fulvestrant h3k36 jq1 lasting methyltransferase modifiers potently premenopausal recruited regulator regulators screen sirna tam tamoxifen valid whsc1 xenograft
Tagcloud (Intersection) ?