BRD7 and BTBD2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		BRD7	BTBD2
Gene Name		bromodomain containing 7	BTB (POZ) domain containing 2
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasmic MRNA Processing Body
	Molecular Function	P53 Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Histone Binding Transcription Regulatory Region DNA Binding Lysine-acetylated Histone Binding	Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Cell Cycle Negative Regulation Of Cell Proliferation Wnt Signaling Pathway Positive Regulation Of Histone Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: AGR2 BARD1 BHLHE40 BRD3 BTBD2 DVL1 FTH1 HAP1 HIST1H2AL HIST2H2BE HIST2H3C HIST3H3 HIST4H4 HNRNPUL1 IRF2 LAMA4 LRIF1 NEFL PAFAH1B3 PCBD1 PSMD11 PTPN13 RBFOX2 RIF1 RPLP1 SERPINB9 TRIM24	26 interactors: BRD7 C14orf1 CCDC90B CDK2 COPS6 CRMP1 DPPA4 EEF1A1 GAPDH GBP2 GDF9 IGSF21 KPNA2 PTN RBM48 SETDB1 SMAD1 SMAD2 TGFBR1 TLE1 TOP1 TP53 TRIM5 UBR1 UNC119 ZNF512B
Entrez ID		29117	55643
HPRD ID		12531	12252
Ensembl ID		ENSG00000166164	ENSG00000133243
Uniprot IDs		Q9NPI1	Q9BX70
PDB IDs		2I7K	3NO8
Enriched GO Terms of Interacting Partners?		Gene Expression Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Retrograde Axon Cargo Transport Transcription, DNA-templated Telomere Maintenance DNA Methylation On Cytosine DNA Modification Chromatin Silencing At RDNA Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Neuromuscular Process Negative Regulation Of Biosynthetic Process Anterograde Axon Cargo Transport Cellular Response To Estrogen Stimulus Chromatin Silencing Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Regulation Of Metabolic Process Axon Cargo Transport Regulation Of Gene Expression, Epigenetic Positive Regulation Of Protein Catabolic Process DNA Methylation Demethylation Mucus Secretion Intracellular Sequestering Of Iron Ion Negative Regulation Of MRNA 3'-end Processing Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Homeostatic Process Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Cell Projection Organization Neuromuscular Process Controlling Balance Convergent Extension Involved In Neural Plate Elongation	Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Organic Substance Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Response To Organic Substance Primary MiRNA Processing Cellular Response To Growth Factor Stimulus Response To Growth Factor Response To Stimulus Cellular Response To Stimulus Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Proliferation Regulation Of RNA Metabolic Process Cell Surface Receptor Signaling Pathway SMAD Protein Complex Assembly Nucleobase-containing Compound Metabolic Process Growth Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Biosynthetic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Viral Process Cell Fate Commitment Transcription, DNA-templated Negative Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process RNA Biosynthetic Process Production Of MiRNAs Involved In Gene Silencing By MiRNA Response To Cholesterol Macromolecule Biosynthetic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Signal Transduction Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Cell Proliferation Positive Regulation Of Cellular Metabolic Process Cellular Response To Interferon-gamma Activin Receptor Signaling Pathway
Tagcloud ?		aza clinically cofactor dc demethylating disturbing ectopic endogenous finding glioma gliomas hypermethylation implicated inactivated inactivation intracranial lrrc4 magnetic microrna mir negatively pathological researches resonance restoration silencing transcriptional transplanted verified
Tagcloud (Difference) ?		aza clinically cofactor dc demethylating disturbing ectopic endogenous finding glioma gliomas hypermethylation implicated inactivated inactivation intracranial lrrc4 magnetic microrna mir negatively pathological researches resonance restoration silencing transcriptional transplanted verified
Tagcloud (Intersection) ?