LGALSL and MAD1L1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LGALSL	MAD1L1
Gene Name		lectin, galactoside-binding-like	MAD1 mitotic arrest deficient-like 1 (yeast)
Image
Gene Ontology Annotations	Cellular Component	Intracellular	Kinetochore Condensed Chromosome Kinetochore Nucleus Nuclear Pore Cytoplasm Centrosome Spindle Cytosol Actin Cytoskeleton Mitotic Spindle
	Molecular Function	Carbohydrate Binding	Protein Binding
	Biological Process		Mitotic Cell Cycle Mitotic Nuclear Division Mitotic Cell Cycle Checkpoint Mitotic Spindle Assembly Checkpoint Cell Division Regulation Of Metaphase Plate Congression
Pathways			Mitotic Spindle Checkpoint Amplification of signal from the kinetochores Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Cell Cycle Checkpoints Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972) Longevity ( 20834067) Schizophrenia ( 22688191) Testicular germ cell tumor ( 23666239)
Protein-Protein Interactions		4 interactors: ACD MAD1L1 TERF2IP TINF2	38 interactors: ALOX5 AMOTL2 BAG5 CCDC94 CCHCR1 COIL CWF19L2 FAM131C HAUS1 HDAC1 HDAC2 LGALSL MAD2L1 MAX MFAP1 MLX NDC80 NEBL NEK2 NINL NONO PSMA1 RNF8 SIN3A SIN3B SPATA2 TEX11 TPM1 TPM3 TPR TRIM29 TSC22D3 TSHZ3 TUBGCP4 UBC UBTF USP15 ZSCAN32
Entrez ID		29094	8379
HPRD ID		13708	04065
Ensembl ID		ENSG00000119862	ENSG00000002822
Uniprot IDs		Q3ZCW2	B3KR41 Q9Y6D9
PDB IDs		2JJ6 3B9C	1GO4 4DZO
Enriched GO Terms of Interacting Partners?		Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Chromosome Organization Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Regulation Of Chromosome Organization Protein Localization To Chromosome Telomere Maintenance Telomere Assembly Protection From Non-homologous End Joining At Telomere Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of DNA Metabolic Process Regulation Of Telomere Maintenance Via Telomerase Regulation Of Organelle Organization Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Replication Protein Localization To Organelle Regulation Of Cellular Component Organization Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Protein ADP-ribosylation Regulation Of Metaphase Plate Congression Positive Regulation Of Single-stranded Telomeric DNA Binding Negative Regulation Of DNA Recombination At Telomere Regulation Of DNA Replication Positive Regulation Of DNA Metabolic Process Chromosome Organization Regulation Of Protein ADP-ribosylation Organelle Organization DNA Metabolic Process Negative Regulation Of Protein Glycosylation Cellular Protein Localization Homeostatic Process Positive Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Regulation Of Protein Glycosylation Positive Regulation Of Telomere Maintenance Protein Localization Negative Regulation Of Glycoprotein Metabolic Process Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Telomerase Activity Positive Regulation Of DNA Biosynthetic Process RNA-dependent DNA Replication Negative Regulation Of DNA Recombination Cellular Localization Regulation Of Double-strand Break Repair Mitotic Spindle Assembly Checkpoint Regulation Of Glycoprotein Biosynthetic Process Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation	Negative Regulation Of Gene Expression Mitotic Cell Cycle Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Mitotic Cell Cycle Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromosome Organization Cell Cycle Process Negative Regulation Of Biosynthetic Process Cell Cycle Organelle Organization Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Histone Deacetylation Protein Deacetylation Negative Regulation Of Ubiquitin-protein Transferase Activity Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression, Epigenetic Mitotic Nuclear Division Regulation Of Ubiquitin-protein Transferase Activity RNA Biosynthetic Process Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Protein Ubiquitination Positive Regulation Of Cell Cycle Process Histone Modification Regulation Of Protein Catabolic Process Regulation Of Cell Cycle Phase Transition Chromatin Modification Regulation Of Apoptotic Process Regulation Of Mitotic Cell Cycle Transcription From RNA Polymerase II Promoter G2/M Transition Of Mitotic Cell Cycle Cell Division Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Proteasomal Protein Catabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Cell Death Regulation Of Cell Cycle Regulation Of Proteolysis Negative Regulation Of Cell Cycle Positive Regulation Of Spindle Checkpoint Transcription, DNA-templated Positive Regulation Of Cell Cycle Chromatin Organization
Tagcloud ?			adverse altered aneuploidy arrest biomarker carcinogenesis characteristic checkpoint checkpoints chromosomal clinicopathological contraindication correlation defects instability mammary microarray mitotic nuclei ones os pacilitaxel predict shorter subtypes taxol undergone whose worse
Tagcloud (Difference) ?			adverse altered aneuploidy arrest biomarker carcinogenesis characteristic checkpoint checkpoints chromosomal clinicopathological contraindication correlation defects instability mammary microarray mitotic nuclei ones os pacilitaxel predict shorter subtypes taxol undergone whose worse
Tagcloud (Intersection) ?