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GRID2 and AP4M1
Number of citations of the paper that reports this interaction (PMID
14572453
)
13
Data Source:
HPRD
(two hybrid, in vivo, in vitro)
GRID2
AP4M1
Gene Name
glutamate receptor, ionotropic, delta 2
adaptor-related protein complex 4, mu 1 subunit
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Ionotropic Glutamate Receptor Complex
Cell Junction
Dendrite
Dendritic Spine
Synapse
Postsynaptic Membrane
Golgi Trans Cisterna
Trans-Golgi Network
Coated Pit
AP-type Membrane Coat Adaptor Complex
Clathrin Adaptor Complex
Extracellular Vesicular Exosome
Molecular Function
Ionotropic Glutamate Receptor Activity
Extracellular-glutamate-gated Ion Channel Activity
Glutamate Receptor Activity
PDZ Domain Binding
Scaffold Protein Binding
Transporter Activity
Biological Process
Transport
Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Glutamate Receptor Signaling Pathway
Regulation Of Neuron Projection Development
Cerebellar Granule Cell Differentiation
Ion Transmembrane Transport
Cellular Protein Localization
Ionotropic Glutamate Receptor Signaling Pathway
Synaptic Transmission, Glutamatergic
Regulation Of Neuron Apoptotic Process
Regulation Of Excitatory Postsynaptic Membrane Potential
Prepulse Inhibition
Intracellular Protein Transport
Golgi To Endosome Transport
Vesicle-mediated Transport
Pathways
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
10 interactors:
AP4M1
DLG2
EML1
GOPC
GRIA1
GRID2IP
GRIK2
GRIK5
MAGI2
PTPN4
13 interactors:
AP4B1
ARF1
CACNG3
CD63
CHTF8
DDX52
GRID2
GRIN2A
GRIN2B
LAMP2
TGOLN2
USP47
ZBTB22
Entrez ID
2895
9179
HPRD ID
06781
03803
Ensembl ID
ENSG00000152208
ENSG00000221838
Uniprot IDs
E9PH24
O43424
C9JC87
O00189
PDB IDs
3L81
Enriched GO Terms of Interacting Partners
?
Receptor Clustering
Synaptic Transmission, Glutamatergic
Ionotropic Glutamate Receptor Signaling Pathway
Glutamate Receptor Signaling Pathway
Negative Regulation Of Synaptic Transmission
Regulation Of Synaptic Vesicle Fusion To Presynaptic Membrane
Neuron-neuron Synaptic Transmission
Regulation Of Synaptic Transmission
Cellular Protein Localization
Protein Retention In ER Lumen
Maintenance Of Protein Localization In Endoplasmic Reticulum
Protein Localization To Membrane
Regulation Of Vesicle-mediated Transport
Long Term Synaptic Depression
Maintenance Of Protein Location In Cell
Maintenance Of Protein Location
Maintenance Of Location In Cell
Regulation Of Synaptic Plasticity
Protein Localization
Synaptic Transmission
Regulation Of Synaptic Vesicle Exocytosis
Regulation Of Vesicle Fusion
Regulation Of Synaptic Vesicle Transport
Cellular Localization
Positive Regulation Of Neuron Apoptotic Process
Membrane Organization
Cellular Response To Glucose Stimulus
Regulation Of Neurotransmitter Secretion
Cell-cell Signaling
Regulation Of Excitatory Postsynaptic Membrane Potential
Positive Regulation Of Neuron Death
Regulation Of Postsynaptic Membrane Potential
Cytoplasmic Sequestering Of CFTR Protein
Cellular Glucose Homeostasis
Cellular Response To Carbohydrate Stimulus
Post-Golgi Vesicle-mediated Transport
Establishment Of Localization In Cell
Regulation Of Phosphatase Activity
Planar Cell Polarity Pathway Involved In Axis Elongation
Negative Regulation Of Signaling
Membrane Depolarization
Protein Localization To Endoplasmic Reticulum
Regulation Of Dephosphorylation
Response To Glucose
Regulation Of Exocytosis
Intracellular Transport
Cytoplasmic Transport
Response To Carbohydrate
Negative Regulation Of Golgi To Plasma Membrane Protein Transport
Glucose Homeostasis
Startle Response
Synaptic Transmission, Glutamatergic
Ionotropic Glutamate Receptor Signaling Pathway
Glutamate Receptor Signaling Pathway
Neuron-neuron Synaptic Transmission
Regulation Of Excitatory Postsynaptic Membrane Potential
Regulation Of Postsynaptic Membrane Potential
Membrane Depolarization
Neuromuscular Process
Regulation Of Synaptic Plasticity
Regulation Of Receptor Internalization
Calcium Ion Transmembrane Transport
Synaptic Transmission
Regulation Of Membrane Potential
Regulation Of Synaptic Transmission
Calcium Ion Transport
Platelet Degranulation
Transport
Cell-cell Signaling
Sensory Perception Of Pain
Protein Localization
Memory
Directional Locomotion
Regulation Of Signaling
Learning
Response To Ethanol
Regulation Of Rubidium Ion Transport
Ion Transmembrane Transport
Regulation Of Endocytosis
Platelet Activation
Pigment Granule Maturation
Endosome To Melanosome Transport
Vesicle-mediated Transport
Cellular Localization
Response To Wounding
Monoubiquitinated Protein Deubiquitination
Positive Regulation Of Integrin-mediated Signaling Pathway
Cellular Pigment Accumulation
Regulation Of Vascular Endothelial Growth Factor Signaling Pathway
Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle
COPI-coated Vesicle Budding
COPI Coating Of Golgi Vesicle
Cerebellar Granule Cell Differentiation
Negative Regulation Of Cell Cycle G2/M Phase Transition
Golgi Vesicle Budding
Metal Ion Transport
Learning Or Memory
Prepulse Inhibition
Serotonin Metabolic Process
Sleep
Tagcloud
?
4q
ataxia
atrophy
biallelic
cerebella
cerebellar
cerebellum
deletions
evolutionarily
exon
eye
fibers
genotyping
heterozygous
homozygosity
homozygous
linkage
movement
movements
ortholog
purkinje
recordings
resemblance
sanger
speech
spines
synapse
tonic
upgaze
Tagcloud (Difference)
?
4q
ataxia
atrophy
biallelic
cerebella
cerebellar
cerebellum
deletions
evolutionarily
exon
eye
fibers
genotyping
heterozygous
homozygosity
homozygous
linkage
movement
movements
ortholog
purkinje
recordings
resemblance
sanger
speech
spines
synapse
tonic
upgaze
Tagcloud (Intersection)
?