AP4M1 and CHTF8

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		AP4M1	CHTF8
Gene Name		adaptor-related protein complex 4, mu 1 subunit	CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Trans Cisterna Trans-Golgi Network Coated Pit AP-type Membrane Coat Adaptor Complex Clathrin Adaptor Complex Extracellular Vesicular Exosome	Nucleus Extracellular Vesicular Exosome
	Molecular Function	Transporter Activity	DNA Binding
	Biological Process	Intracellular Protein Transport Golgi To Endosome Transport Vesicle-mediated Transport	DNA Replication Cell Cycle
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: AP4B1 ARF1 CACNG3 CD63 CHTF8 DDX52 GRID2 GRIN2A GRIN2B LAMP2 TGOLN2 USP47 ZBTB22	6 interactors: AP4M1 DSCC1 EIF4EBP1 PCNA RFC3 WBP4
Entrez ID		9179	54921
HPRD ID		03803	16797
Ensembl ID		ENSG00000221838	ENSG00000168802
Uniprot IDs		C9JC87 O00189	P0CG13
PDB IDs		3L81
Enriched GO Terms of Interacting Partners?		Startle Response Synaptic Transmission, Glutamatergic Ionotropic Glutamate Receptor Signaling Pathway Glutamate Receptor Signaling Pathway Neuron-neuron Synaptic Transmission Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Membrane Depolarization Neuromuscular Process Regulation Of Synaptic Plasticity Regulation Of Receptor Internalization Calcium Ion Transmembrane Transport Synaptic Transmission Regulation Of Membrane Potential Regulation Of Synaptic Transmission Calcium Ion Transport Platelet Degranulation Transport Cell-cell Signaling Sensory Perception Of Pain Protein Localization Memory Directional Locomotion Regulation Of Signaling Learning Response To Ethanol Regulation Of Rubidium Ion Transport Ion Transmembrane Transport Regulation Of Endocytosis Platelet Activation Pigment Granule Maturation Endosome To Melanosome Transport Vesicle-mediated Transport Cellular Localization Response To Wounding Monoubiquitinated Protein Deubiquitination Positive Regulation Of Integrin-mediated Signaling Pathway Cellular Pigment Accumulation Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Cerebellar Granule Cell Differentiation Negative Regulation Of Cell Cycle G2/M Phase Transition Golgi Vesicle Budding Metal Ion Transport Learning Or Memory Prepulse Inhibition Serotonin Metabolic Process Sleep	Nucleotide-excision Repair, DNA Gap Filling Telomere Maintenance Via Semi-conservative Replication Nuclear DNA Replication Telomere Maintenance Via Recombination Mitotic Cell Cycle Mitotic Recombination DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening DNA Replication Transcription-coupled Nucleotide-excision Repair Cell Cycle Process Cell Cycle Telomere Maintenance Nucleotide-excision Repair Positive Regulation Of Deoxyribonuclease Activity DNA-dependent DNA Replication DNA Biosynthetic Process Regulation Of DNA Replication Mitotic Cell Cycle Process Leading Strand Elongation G1/S Transition Of Mitotic Cell Cycle Post-translational Protein Acetylation Maintenance Of Mitotic Sister Chromatid Cohesion IRES-dependent Translational Initiation Cap-independent Translational Initiation DNA Recombination Chromosome Organization DNA Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cytoplasmic Translational Initiation Translesion Synthesis Mitotic Sister Chromatid Cohesion Cytoplasmic Translation DNA Synthesis Involved In DNA Repair MRNA Cis Splicing, Via Spliceosome Golgi To Endosome Transport Negative Regulation Of Translational Initiation Postreplication Repair TOR Signaling Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Sister Chromatid Cohesion Response To Ischemia DNA Repair Cellular Homeostasis Positive Regulation Of Nuclease Activity Nucleobase-containing Compound Metabolic Process
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