AP4M1 and USP47

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		AP4M1	USP47
Gene Name		adaptor-related protein complex 4, mu 1 subunit	ubiquitin specific peptidase 47
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Trans Cisterna Trans-Golgi Network Coated Pit AP-type Membrane Coat Adaptor Complex Clathrin Adaptor Complex Extracellular Vesicular Exosome	Nucleus Cytoplasm SCF Ubiquitin Ligase Complex
	Molecular Function	Transporter Activity	Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Protein Binding WD40-repeat Domain Binding
	Biological Process	Intracellular Protein Transport Golgi To Endosome Transport Vesicle-mediated Transport	Base-excision Repair Cellular Response To DNA Damage Stimulus Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Growth Cellular Response To UV Monoubiquitinated Protein Deubiquitination Response To Drug Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: AP4B1 ARF1 CACNG3 CD63 CHTF8 DDX52 GRID2 GRIN2A GRIN2B LAMP2 TGOLN2 USP47 ZBTB22	5 interactors: AP4M1 MED29 MED9 PLA2G2A SNCA
Entrez ID		9179	55031
HPRD ID		03803	11668
Ensembl ID		ENSG00000221838	ENSG00000170242
Uniprot IDs		C9JC87 O00189	Q96K76
PDB IDs		3L81
Enriched GO Terms of Interacting Partners?		Startle Response Synaptic Transmission, Glutamatergic Ionotropic Glutamate Receptor Signaling Pathway Glutamate Receptor Signaling Pathway Neuron-neuron Synaptic Transmission Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Membrane Depolarization Neuromuscular Process Regulation Of Synaptic Plasticity Regulation Of Receptor Internalization Calcium Ion Transmembrane Transport Synaptic Transmission Regulation Of Membrane Potential Regulation Of Synaptic Transmission Calcium Ion Transport Platelet Degranulation Transport Cell-cell Signaling Sensory Perception Of Pain Protein Localization Memory Directional Locomotion Regulation Of Signaling Learning Response To Ethanol Regulation Of Rubidium Ion Transport Ion Transmembrane Transport Regulation Of Endocytosis Platelet Activation Pigment Granule Maturation Endosome To Melanosome Transport Vesicle-mediated Transport Cellular Localization Response To Wounding Monoubiquitinated Protein Deubiquitination Positive Regulation Of Integrin-mediated Signaling Pathway Cellular Pigment Accumulation Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Cerebellar Granule Cell Differentiation Negative Regulation Of Cell Cycle G2/M Phase Transition Golgi Vesicle Budding Metal Ion Transport Learning Or Memory Prepulse Inhibition Serotonin Metabolic Process Sleep	Negative Regulation Of Thrombin Receptor Signaling Pathway Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Serotonin Uptake Negative Regulation Of Dopamine Metabolic Process Negative Regulation Of Cellular Respiration Negative Regulation Of Oxidative Phosphorylation Negative Regulation Of Synaptic Transmission, Dopaminergic Response To Iron(II) Ion Cellular Response To Copper Ion Regulation Of Synaptic Vesicle Recycling Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Oxidative Phosphorylation Positive Regulation Of Inositol Phosphate Biosynthetic Process Regulation Of Hydrogen Peroxide Metabolic Process Dopamine Transport Regulation Of Glutamate Secretion Dopamine Biosynthetic Process Low-density Lipoprotein Particle Remodeling Phospholipid Metabolic Process Negative Regulation Of Monooxygenase Activity Neurotransmitter Uptake Regulation Of Cellular Respiration Microglial Cell Activation Extracellular Fibril Organization Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Synaptic Transmission, Dopaminergic Behavioral Response To Cocaine Phosphatidylinositol Acyl-chain Remodeling Regulation Of Neurotransmitter Uptake Phosphatidylglycerol Acyl-chain Remodeling Phosphatidylserine Acyl-chain Remodeling Negative Regulation Of Microtubule Polymerization Positive Regulation Of Neurotransmitter Secretion Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Acyl-CoA Biosynthetic Process Cellular Response To Epinephrine Stimulus Golgi To Endosome Transport Positive Regulation Of Receptor Recycling Catecholamine Biosynthetic Process Regulation Of Synaptic Transmission, Dopaminergic Response To Epinephrine Regulation Of Dopamine Metabolic Process Response To Bacterium Response To Magnesium Ion Phosphatidylethanolamine Acyl-chain Remodeling
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