GRID2 and GRID2IP

Number of citations of the paper that reports this interaction (PMID 11826110)
20

Data Source:
BioGRID (two hybrid, pull down, affinity chromatography technology)

		GRID2	GRID2IP
Gene Name		glutamate receptor, ionotropic, delta 2	glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Ionotropic Glutamate Receptor Complex Cell Junction Dendrite Dendritic Spine Synapse Postsynaptic Membrane	Cell Junction Dendritic Spine Postsynaptic Membrane
	Molecular Function	Ionotropic Glutamate Receptor Activity Extracellular-glutamate-gated Ion Channel Activity Glutamate Receptor Activity PDZ Domain Binding Scaffold Protein Binding
	Biological Process	Transport Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Glutamate Receptor Signaling Pathway Regulation Of Neuron Projection Development Cerebellar Granule Cell Differentiation Ion Transmembrane Transport Cellular Protein Localization Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Regulation Of Neuron Apoptotic Process Regulation Of Excitatory Postsynaptic Membrane Potential Prepulse Inhibition	Long Term Synaptic Depression
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		10 interactors: AP4M1 DLG2 EML1 GOPC GRIA1 GRID2IP GRIK2 GRIK5 MAGI2 PTPN4	1 interactors: GRID2
Entrez ID		2895	392862
HPRD ID		06781	19587
Ensembl ID		ENSG00000152208
Uniprot IDs		E9PH24 O43424	A4D2P6
PDB IDs
Enriched GO Terms of Interacting Partners?		Receptor Clustering Synaptic Transmission, Glutamatergic Ionotropic Glutamate Receptor Signaling Pathway Glutamate Receptor Signaling Pathway Negative Regulation Of Synaptic Transmission Regulation Of Synaptic Vesicle Fusion To Presynaptic Membrane Neuron-neuron Synaptic Transmission Regulation Of Synaptic Transmission Cellular Protein Localization Protein Retention In ER Lumen Maintenance Of Protein Localization In Endoplasmic Reticulum Protein Localization To Membrane Regulation Of Vesicle-mediated Transport Long Term Synaptic Depression Maintenance Of Protein Location In Cell Maintenance Of Protein Location Maintenance Of Location In Cell Regulation Of Synaptic Plasticity Protein Localization Synaptic Transmission Regulation Of Synaptic Vesicle Exocytosis Regulation Of Vesicle Fusion Regulation Of Synaptic Vesicle Transport Cellular Localization Positive Regulation Of Neuron Apoptotic Process Membrane Organization Cellular Response To Glucose Stimulus Regulation Of Neurotransmitter Secretion Cell-cell Signaling Regulation Of Excitatory Postsynaptic Membrane Potential Positive Regulation Of Neuron Death Regulation Of Postsynaptic Membrane Potential Cytoplasmic Sequestering Of CFTR Protein Cellular Glucose Homeostasis Cellular Response To Carbohydrate Stimulus Post-Golgi Vesicle-mediated Transport Establishment Of Localization In Cell Regulation Of Phosphatase Activity Planar Cell Polarity Pathway Involved In Axis Elongation Negative Regulation Of Signaling Membrane Depolarization Protein Localization To Endoplasmic Reticulum Regulation Of Dephosphorylation Response To Glucose Regulation Of Exocytosis Intracellular Transport Cytoplasmic Transport Response To Carbohydrate Negative Regulation Of Golgi To Plasma Membrane Protein Transport Glucose Homeostasis	Cerebellar Granule Cell Differentiation Prepulse Inhibition Cerebellar Granular Layer Morphogenesis Cerebellar Granular Layer Development Cerebellar Cortex Formation Startle Response Cell Differentiation In Hindbrain Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cerebellar Cortex Morphogenesis Synaptic Transmission, Glutamatergic Ionotropic Glutamate Receptor Signaling Pathway Cerebellum Morphogenesis Hindbrain Morphogenesis Glutamate Receptor Signaling Pathway Cerebellar Cortex Development Neuron-neuron Synaptic Transmission Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Cerebellum Development Membrane Depolarization Metencephalon Development Neuromuscular Process Hindbrain Development Central Nervous System Neuron Differentiation Regulation Of Neuron Apoptotic Process Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Regulation Of Membrane Potential Regulation Of Neuron Death Regulation Of Neuron Projection Development
Tagcloud ?		4q ataxia atrophy biallelic cerebella cerebellar cerebellum deletions evolutionarily exon eye fibers genotyping heterozygous homozygosity homozygous linkage movement movements ortholog purkinje recordings resemblance sanger speech spines synapse tonic upgaze
Tagcloud (Difference) ?		4q ataxia atrophy biallelic cerebella cerebellar cerebellum deletions evolutionarily exon eye fibers genotyping heterozygous homozygosity homozygous linkage movement movements ortholog purkinje recordings resemblance sanger speech spines synapse tonic upgaze
Tagcloud (Intersection) ?