GRB2 and CEBPA

Number of citations of the paper that reports this interaction (PubMedID 34189442)
73

Data Source:
BioGRID (unspecified method)

		GRB2	CEBPA
Description		growth factor receptor bound protein 2	CCAAT enhancer binding protein alpha
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endosome Golgi Apparatus Centrosome Cytosol Plasma Membrane Cell-cell Junction Cell Cortex COP9 Signalosome Vesicle Membrane Membrane Extracellular Exosome Grb2-EGFR Complex	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Nuclear Matrix Protein-containing Complex Rb-E2F Complex CHOP-C/EBP Complex RNA Polymerase II Transcription Regulator Complex C/EBP Complex
	Molecular Function	Phosphotyrosine Residue Binding RNA Binding Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Guanyl-nucleotide Exchange Factor Adaptor Activity Epidermal Growth Factor Receptor Binding Neurotrophin TRKA Receptor Binding Protein Binding SH3 Domain Binding Protein Kinase Binding Protein Phosphatase Binding Protein Domain Specific Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Insulin Receptor Substrate Binding Ephrin Receptor Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Kinase Binding Protein Domain Specific Binding Chromatin DNA Binding Identical Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding Sequence-specific DNA Binding Protein-containing Complex Binding Protein Heterodimerization Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding HMG Box Domain Binding STAT Family Protein Binding DNA-binding Transcription Factor Binding
	Biological Process	Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Ras Protein Signal Transduction Insulin Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Schwann Cell Development Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization T Cell Costimulation Receptor Internalization Endodermal Cell Differentiation T Cell Activation Natural Killer Cell Mediated Cytotoxicity Myelination Signal Transduction In Response To DNA Damage Regulation Of MAPK Cascade Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Insulin-like Growth Factor Receptor Signaling Pathway Anatomical Structure Formation Involved In Morphogenesis B Cell Receptor Signaling Pathway Branching Involved In Labyrinthine Layer Morphogenesis Cellular Response To Ionizing Radiation Positive Regulation Of Reactive Oxygen Species Metabolic Process	Urea Cycle Negative Regulation Of Transcription By RNA Polymerase II Liver Development Embryonic Placenta Development Epithelial Cell Maturation Osteoblast Development Generation Of Precursor Metabolites And Energy DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase I Acute-phase Response Mitochondrion Organization Notch Signaling Pathway Response To Nutrient Memory Cholesterol Metabolic Process Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Cytokine-mediated Signaling Pathway Myeloid Cell Differentiation Cell Differentiation Macrophage Differentiation Lung Development Granulocyte Differentiation Animal Organ Regeneration Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Vitamin B2 Regulation Of Cell Population Proliferation Glucose Homeostasis Positive Regulation Of Macrophage Activation Fat Cell Differentiation Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Cell Cycle Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Inner Ear Development Positive Regulation Of Inflammatory Response White Fat Cell Differentiation Brown Fat Cell Differentiation Regulation Of Cell Cycle Lipid Homeostasis Interleukin-6-mediated Signaling Pathway White Fat Cell Proliferation Cellular Response To Lithium Ion Cellular Response To Tumor Necrosis Factor Hematopoietic Stem Cell Proliferation Cellular Response To Xenobiotic Stimulus Response To Dexamethasone Response To Phenylpropanoid Energy Homeostasis Integrated Stress Response Signaling Negative Regulation Of Hematopoietic Stem Cell Proliferation Positive Regulation Of DNA-templated Transcription Initiation
Pathways		Interleukin-15 signaling Interleukin-15 signaling Signaling by CSF3 (G-CSF) Signaling by CSF3 (G-CSF) STAT5 activation downstream of FLT3 ITD mutants Signaling by FLT3 ITD and TKD mutants Signaling by FLT3 ITD and TKD mutants Signaling by ALK fusions and activated point mutants Signaling by LTK	Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of granulopoiesis Transcriptional regulation of granulopoiesis MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Drugs		Pegademase 4-[(10s,14s,18s)-18-(2-Amino-2-Oxoethyl)-14-(1-Naphthylmethyl)-8,17,20-Trioxo-7,16,19-Triazaspiro[5.14]Icos-11-En-10-Yl]Benzylphosphonic Acid
Diseases			Acute myeloid leukemia (AML)
GWAS		Aspartate aminotransferase levels ( 33547301) Deep white matter hyperintensities ( 32517579) Multiple sclerosis ( 31604244) Systemic lupus erythematosus ( 26502338 28714469 29848360) Systemic sclerosis ( 31672989) Triglyceride levels ( 32203549) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172)	A body shape index ( 34021172) Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Apolipoprotein A1 levels ( 32203549) Asthma ( 34103634 31959851 30929738) Asthma (adult onset) ( 31036433 30929738) Asthma (childhood onset) ( 31036433 30929738) Basophil count ( 28031487) Birth weight ( 31043758) Hip index ( 34021172) Mastocytosis (KIT D816V positive) ( 33421400) Red blood cell count ( 29403010) Visceral adipose tissue volume ( 34128465) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 28448500 25673412) White blood cell count (basophil) ( 29403010 28158719)
Interacting Genes		397 interacting genes: A2M ABI3 ABI3BP ABL1 ABL2 ACAP1 ADA ADAM12 ADAM15 ADRB1 ADRB2 AEBP1 AGR2 AGT AHSG AJUBA ALAS2 ALOX5 AMBP ANKRD13A ANKRD23 ANXA2 AP4S1 APCS APOH APP AR ARHGAP17 ARHGAP32 ARHGAP35 ARID5A ASAP1 ASAP2 AUNIP AXL B2M BCAR1 BCL2A1 BCR BLNK BPGM BTG1 C1orf94 C21orf58 C21orf91 CALD1 CASC3 CASP2 CBL CBLB CBLC CCDC28B CCL5 CD164 CD19 CD22 CD247 CD28 CD2AP CD72 CDC42 CDKN1B CEBPA CFH CHRM4 CHRND CKS2 CLNK CLU COPB1 COX6A1 CPSF7 CRBN CRK CRKL CSF1R CSF3R CSN2 CTTN CUTA DAB2 DAG1 DCTN1 DCTN2 DDIT4L DDX17 DLGAP1 DNAJA3 DNAJB11 DNM1 DNM2 DOCK4 DPPA4 DRD3 DRD4 DTX1 DTX3 DVL2 E2F2 ECHS1 EFHC2 EGF EGFR ELK1 ENO1 EP300 EPHA2 EPHB1 EPHB2 EPHB6 EPOR EPS15 EPS8 ERBB2 ERBB3 ERBB4 ESD ESR1 ETV6 FABP1 FASLG FCGR2A FCGR2B FGFR1 FGFR3 FH FHOD1 FLT1 FLT3 FLT4 FN1 FRS2 FRS3 FTH1 FTL FYN GAB1 GAB2 GAB3 GC GGN GHR GIT1 GPANK1 GRAP2 GRB7 GSTK1 H1-0 H2AX HCLS1 HELZ HIPK3 HNRNPC HNRNPK HOMEZ HP HRAS HTT IK IKZF3 IL2RB INCA1 INPP5D IRS1 IRS2 IRS4 ITGA2B ITGA6 ITGB4 ITIH4 ITK JAK1 JAK2 KDR KHDRBS1 KHDRBS2 KIAA0408 KIAA1549L KIF3A KIT KPNA2 KPRP KRT8 LAT LAT2 LAX1 LCP2 LIME1 LMO2 LNX1 LNX2 LY6G6F LZTS2 MAP1A MAP2 MAP4K1 MAP4K5 MAPK1 MAPK12 MAPK14 MAPK9 MED19 MED28 MEI4 MERTK MET METTL27 MIA2 MICAL1 MLXIPL MRE11 MS4A2 MSI2 MST1R MT-ATP8 MT-ND4 MTA1 MTA3 MUC1 MYG1 MYH11 MYO18A MYOZ1 NADK NAP1L5 NCKIPSD NCL NEU3 NFYB NGFR NIF3L1 NKD2 NPM1 NTRK1 NUTM2F OCRL OLIG1 PACRGL PAG1 PAK1 PAK2 PAK4 PBXIP1 PCDHB5 PDCD6IP PDE4D PDE6G PDGFRB PHACTR4 PHC2 PHETA1 PIK3AP1 PIK3C2B PIK3CG PIK3R1 PIK3R2 PIK3R3 PLCG1 PLEKHA7 PNMA5 PNRC1 POLR1D POLR2A POMP PON2 PPP3CA PRAP1 PRKAB1 PRKAR1A PRNP PRR22 PRR5-ARHGAP8 PRRC2A PRRG4 PTK2 PTK2B PTPN1 PTPN11 PTPN12 PTPN22 PTPN6 PTPRA PTPRC PTPRE PXN RALGPS1 RAPGEF1 RAPSN RASA1 RBBP6 RBM33 RBP4 REL REPS1 REPS2 RET RHOU RIF1 RNF10 RNF208 RPA1 RPS6KA1 SELL SF3A2 SF3B4 SH2B1 SH2B2 SH2B3 SH2D1A SH2D4A SH3BP2 SH3D19 SH3KBP1 SHANK3 SHB SHBG SHC1 SHC2 SHC3 SHC4 SHKBP1 SIGLEC7 SIT1 SKAP1 SLC1A2 SLX1A SNRNP200 SNTA1 SOCS1 SOCS7 SOS1 SOS2 SPATA2L SPRY1 SPRY2 SPTBN1 SRC SS18 STAMBP STK32C STRADB SYK SYN1 SYNCRIP SYNJ1 SYNJ2 SYP TBC1D3B TBC1D3G TCEAL8 TCERG1 TEK TF TFG TLE5 TNFRSF1A TNK2 TOM1L1 TP53BP2 TP63 TRAT1 TRIB3 TRIM27 TSC2 TSPAN2 TUB TXK UBA1 UBA52 UBC UQCC2 USP53 USP6NL USP8 VAV1 VAV2 VAV3 VIM VPS37C WAS WASF1 WASF2 WASL WBP11 WDFY3 WDR1 WDR44 WIPF1 WIPF2 YLPM1 ZAP70 ZBTB12 ZBTB7B ZMAT1 ZNF341 ZNF474 ZNF620	831 interacting genes: AARS1 ABCE1 ABCF1 ACLY ACSL1 ACTG1 ACTN1 ACTN4 ACTR1A ACTR2 ADAR AHCY AHSA1 AIMP2 AIP AK6 ALDOA ALKBH5 ALYREF ANAPC7 ANLN ANXA5 ANXA6 AP1B1 AP2B1 AP2M1 APEH APEX1 AR ARHGAP15 ARHGDIA ARHGDIB ARHGEF2 ARL6IP4 ARPC1B ARPC3 ASNS ATF2 ATF4 ATF5 ATIC ATP1A1 ATP2A2 ATXN2 ATXN2L AURKA BAG1 BAG6 BANF1 BATF BATF2 BATF3 BCAP31 BCAT1 BCL2L2 BCLAF1 BIN2 BLMH BTF3 BTF3L4 BUB3 BUD23 BUD31 BZW1 BZW2 C11orf58 C19orf53 C1QBP C2orf49 CAB39 CACYBP CAD CALU CAMK2G CAND1 CAP1 CAPG CAPRIN1 CAPZA1 CAPZB CC2D1A CCAR2 CCDC12 CCDC7 CCNB1 CCT2 CCT3 CCT4 CCT5 CCT6A CCT7 CCT8 CCZ1 CDC42 CDK1 CDK13 CDK2 CDK4 CDK7 CDK8 CDK9 CDKN1A CDKN2AIP CDKN3 CDX1 CEBPB CEBPD CEBPE CEBPG CELF1 CELF2 CEP170 CGGBP1 CHD4 CHD8 CHEK1 CHMP4B CHMP5 CHTOP CIAPIN1 CIRBP CIT CKAP5 CLASP1 CLIC1 CLINT1 CLTA CLTB CLTC CMSS1 CNOT1 COPS3 COPS4 COPS5 CORO1A CORO1C CPNE1 CPSF6 CPSF7 CREBBP CRIPT CSDE1 CSNK1A1 CSNK2A1 CSNK2A2 CSTF3 CTNNB1 CTPS1 CUL1 CUL3 CUTA CZIB DARS1 DAZAP1 DBP DCD DCPS DCXR DDX1 DDX17 DDX19B DDX23 DDX39A DDX3X DDX41 DDX49 DDX5 DDX55 DDX6 DEK DHX15 DIDO1 DIMT1 DNAJB1 DNAJC8 DNAJC9 DNM2 DNMT1 DOCK2 DOCK8 DPP3 DRG1 DTYMK DYNC1H1 DYNC1LI1 DYNLRB1 ECPAS EDC4 EDF1 EEF1A1 EEF1B2 EEF1D EEF1E1 EEF1G EEF2 EEFSEC EIF1 EIF2A EIF2S1 EIF2S2 EIF2S3 EIF4A1 EIF4A3 EIF4B EIF4E EIF4G2 EIF4H EIF5 EIF5B ELAVL1 ELMO1 ELOB ELOC EMG1 ENY2 EP300 EP400 EPRS1 ERGIC3 ERP29 ESR1 ETF1 ETV6 EVL EWSR1 EXOSC10 EZR FAM120A FAM136A FAM32A FAM76B FAM98B FANCI FARSB FASN FDPS FEN1 FIP1L1 FKBP3 FKBP4 FKBP5 FLNA FLYWCH2 FNBP1 FOS FOSL1 FOXK1 FRG1 FUBP1 FUBP3 FUS G3BP1 G3BP2 GABARAPL2 GABPA GABPB1 GAPDH GARS1 GATA2 GATAD2A GBE1 GDI2 GET4 GLO1 GLRX3 GLTP GMFG GMNN GMPS GOPC GRB2 GRWD1 GSK3B GSN GSPT1 GSTP1 GTF2F1 GTF2F2 GTF2I GTPBP1 GTSF1 H1-2 H1-5 H2AC20 H2BC15 H3-3A H4C1 HADHA HADHB HAT1 HCFC1 HDAC1 HDAC2 HDGF HDLBP HEATR3 HEBP2 HELLS HEXIM1 HLTF HMGA1 HMGB1 HMGB2 HMGB3 HMGCS1 HMGN1 HMGN2 HMGN4 HMMR HNF1A HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPAB HNRNPD HNRNPDL HNRNPK HNRNPL HNRNPLL HNRNPR HNRNPU HNRNPUL1 HOMER3 HPCAL1 HPRT1 HSD17B4 HSPA1B HSPA4 HSPH1 HYOU1 IARS1 IFI16 IGF2BP1 IGF2BP2 IGF2BP3 IK ILF2 ILF3 ILK IMPDH2 INPP5D INTS12 IPO11 IPO7 IQGAP1 IRF2BP1 IRF2BP2 ITPA KARS1 KAT2A KAT8 KCNAB2 KHDRBS1 KHSRP KIF11 KIF2A KIF2C KIF4A KIF5B KIFC1 KNTC1 KPNB1 LARP1 LARS1 LASP1 LCP1 LDHA LDHB LIG1 LIMD2 LMAN1 LRWD1 LSM12 LSM14A LSM14B LSM2 LSM5 LSM6 LSM7 MAGOHB MAP2K7 MAP4 MAP7D1 MAPK1 MAPK8 MARS1 MAT2A MAT2B MBNL1 MCM4 MCM5 MCM7 MCTS1 MED1 MED10 MED12 MED14 MED15 MED16 MED17 MED21 MED22 MED23 MED24 MED27 MED28 MED29 MED4 MED6 MED8 METAP2 MIF MITD1 MKI67 MLKL MNDA MORC2 MORF4L1 MPO MRE11 MRTO4 MSH2 MSH6 MSN MSX2 MTA2 MTHFD1 MTPN MTREX MVK MYC MYCBP2 MYL6 MZT2B NAA10 NAA15 NAA50 NAE1 NARS1 NCAPD3 NCAPG2 NCF1 NCOA6 NEDD1 NEK6 NELFA NELFB NELFE NFYA NHERF1 NIFK NME2 NOC4L NOLC1 NONO NOP14 NOP2 NOP58 NOSIP NPEPPS NR3C1 NSFL1C NSUN2 NSUN5 NTPCR NUCKS1 NUDC NUDT16L1 NUDT21 NUP153 NUP50 NUP93 NUSAP1 NUTF2 NXF1 OLA1 ORC3 ORC5 ORC6 OTUB1 PA2G4 PABPC1 PABPC4 PAF1 PAICS PAK2 PARP1 PCBP2 PCLAF PCM1 PCMT1 PCNP PDAP1 PDCD5 PDCD6 PDIA3 PDIA4 PDS5A PDS5B PEBP1 PES1 PFDN1 PFDN2 PFDN5 PFDN6 PFKL PFKM PGAM1 PGK1 PHF6 PHGDH PIAS1 PIN1 PIN4 PKM PLIN3 PLK1 PLRG1 PNP POLDIP3 POLR1D PPA1 PPAT PPIB PPIH PPIL2 PPME1 PPP2CA PPP3CA PPP4R2 PPP4R3A PPP5C PQBP1 PRAM1 PRC1 PRDX1 PRKDC PRKRIP1 PRMT1 PRPF19 PRPF3 PRPF31 PRPF38B PRPF39 PRPF4 PRPF6 PRPS1 PRRC2A PRRC2C PSIP1 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB7 PSMC1 PSMC3 PSMC4 PSMC6 PSMD10 PSMD11 PSMD12 PSMD14 PSMD6 PSMD7 PSME1 PSME2 PSME3 PSMG1 PSPC1 PTBP1 PUF60 PUM3 PURB PYGL QKI RAB10 RAB2A RAB3GAP2 RAC1 RAD23A RAD23B RAD50 RAE1 RANBP1 RANBP2 RARA RARB RARS1 RASGRF1 RASGRP2 RAVER1 RB1 RBL1 RBM14 RBM15 RBM17 RBM22 RBM26 RBM27 RBM28 RBM3 RBM33 RBM39 RBMX RCC1 RCC2 RCOR1 RECQL RFC1 RFC2 RFC3 RFC4 RFC5 RHOA RHOG RNGTT RNH1 RPA1 RPA2 RPL9 RPP30 RPS28 RPS29 RRM1 RSL1D1 RTCB RTRAF RUNX1 RUVBL2 S100A11 S100P SAE1 SAFB SAFB2 SAR1A SARNP SART1 SBDS SCAF4 SCP2 SEH1L SEPTIN14 SEPTIN2 SEPTIN6 SEPTIN9 SERF2 SF1 SF3A1 SF3A2 SF3B6 SFPQ SIN3A SKP2 SLAIN2 SLBP SLC25A5 SLC3A2 SLFN11 SMAD3 SMAD4 SMARCA2 SMARCA4 SMARCC2 SMARCD2 SMARCE1 SMC1A SMC2 SMC3 SMC4 SMCHD1 SMNDC1 SMS SMU1 SND1 SNRNP200 SNRNP40 SNRNP70 SNRPA SNRPA1 SNRPB2 SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNW1 SNX9 SORD SOX10 SOX8 SPAST SPI1 SPR SRA1 SRM SRP14 SRP19 SRP54 SRP68 SRP72 SRP9 SRRM2 SRSF7 SSB SSBP1 SSRP1 STAT1 STAU1 STEEP1 STK10 STMN1 STRAP SUB1 SUGP1 SUGP2 SUGT1 SUMO1 SUMO2 SUMO3 SURF4 SYK SYNCRIP TADA3 TALDO1 TAOK3 TARS1 TBCA TBL1XR1 TCEA1 TCERG1 TCP1 TEX30 THAP11 THOC2 THRAP3 THYN1 TIAL1 TIPRL TKT TLN1 TM9SF3 TMA16 TMA7 TMED10 TMPO TNPO2 TNPO3 TOGARAM2 TOMM34 TOP1 TOP2A TOP2B TP53 TP53BP1 TPI1 TPP2 TPT1 TPX2 TRIB2 TRIM25 TRIM33 TRIM4 TRIR TRRAP TSN TSNAX TTC9C TTF2 TTLL12 TUBB4A TUBB4B TUBG1 TUBGCP2 TUBGCP3 TWF2 TXLNA TXLNG TXN TXNDC5 TXNL1 TXNRD1 U2SURP UBA1 UBA2 UBE2I UBE2K UBQLN1 UBR5 UBTF UBXN1 UCHL3 UNG UPF1 UPF3B USP14 USP22 USP39 VARS1 VASP WARS1 WBP11 WDR74 WDR82 WIPF1 WRNIP1 XPO1 XPO5 XPOT XRCC5 XRCC6 XRN2 YBX1 YY1 ZBTB16 ZC3H11A ZC3H15 ZFR ZMAT2 ZNF207 ZRANB2 ZW10 ZYX
Entrez ID		2885	1050
HPRD ID		00150	00296
Ensembl ID		ENSG00000177885	ENSG00000245848
Uniprot IDs		B0LPF3 P62993	P49715
PDB IDs		1AZE 1BM2 1BMB 1CJ1 1FHS 1FYR 1GCQ 1GFC 1GFD 1GHU 1GRI 1IO6 1JYQ 1JYR 1JYU 1QG1 1TZE 1X0N 1ZFP 2AOA 2AOB 2H46 2H5K 2HUW 2VVK 2VWF 2W0Z 3C7I 3IMD 3IMJ 3IN7 3IN8 3KFJ 3MXC 3MXY 3N7Y 3N84 3N8M 3OV1 3OVE 3S8L 3S8N 3S8O 3WA4 4P9V 4P9Z 5CDW 6ICG 6ICH 6SDF 6VK2 6WM1 6WO2 7MPH 8DGO	6DC0 8K8C
Enriched GO Terms of Interacting Partners?		Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Enzyme-linked Receptor Protein Signaling Pathway Signal Transduction Protein Tyrosine Kinase Activity SH3 Domain Binding Regulation Of Intracellular Signal Transduction Intracellular Signal Transduction Regulation Of Signal Transduction Plasma Membrane Regulation Of Signaling Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Cell Communication Phosphotyrosine Residue Binding Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of MAPK Cascade SH2 Domain Binding Immune Response-activating Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Activity Antigen Receptor-mediated Signaling Pathway Regulation Of Cellular Component Organization Positive Regulation Of Cellular Component Organization Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Signaling Positive Regulation Of Signal Transduction Intracellular Signaling Cassette Peptidyl-tyrosine Phosphorylation Regulation Of Immune System Process Positive Regulation Of Cell Communication Regulation Of Immune Response Cytosol Protein Kinase Activity T Cell Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Positive Regulation Of Immune System Process Immune System Process Protein Binding Immune Response-activating Signaling Pathway Regulation Of Cell Population Proliferation Regulation Of Multicellular Organismal Process Regulation Of Programmed Cell Death Positive Regulation Of Multicellular Organismal Process Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of MAPK Cascade Regulation Of Apoptotic Process Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Cell Migration Activation Of Immune Response Response To Growth Factor	RNA Binding Nucleoplasm Nucleus Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Cytosol Cytoplasm MRNA Metabolic Process Macromolecule Metabolic Process MRNA Processing RNA Splicing RNA Processing Spliceosomal Complex RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Nucleic Acid Binding Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Protein Binding MRNA Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Protein-containing Complex Organization Catalytic Step 2 Spliceosome Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Nucleotide Binding ATP Binding Positive Regulation Of Macromolecule Biosynthetic Process Extracellular Exosome Protein-containing Complex Assembly Positive Regulation Of RNA Metabolic Process Ribonucleoprotein Complex Positive Regulation Of Biosynthetic Process Cadherin Binding Regulation Of DNA Metabolic Process Chromatin Binding Ficolin-1-rich Granule Lumen Nucleolus Regulation Of Gene Expression Cellular Component Assembly Proteasome Complex Nuclear Speck Negative Regulation Of Macromolecule Metabolic Process Cytoplasmic Stress Granule ATP Hydrolysis Activity Positive Regulation Of RNA Biosynthetic Process
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