TAF7 and TRIM22

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		TAF7	TRIM22
Gene Name		TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa	tripartite motif containing 22
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Transcription Factor TFIID Complex Golgi Apparatus Positive Transcription Elongation Factor Complex B Transcription Factor TFTC Complex MLL1 Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Cajal Body Nuclear Speck
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Histone Acetyltransferase Binding Vitamin D Receptor Binding Transcription Regulatory Region DNA Binding Thyroid Hormone Receptor Binding	Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Zinc Ion Binding Ligase Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Spermine Transport DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Protein Kinase Activity Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Histone Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Immune Response Response To Virus Viral Process Protein Ubiquitination Cytokine-mediated Signaling Pathway Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Protein Trimerization Negative Regulation Of Nucleic Acid-templated Transcription
Pathways			Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: AHR CDK7 CDK9 CPSF1 FAU GATA1 HIST3H3 HSF1 IKBKG MAP1LC3B RBM6 SETD7 TAF1 TAF10 TAF11 TAF12 TAF15 TAF2 TAF4 TAF5 TAF6 TAF8 TAF9 TRIM22 TRIM24 YWHAE ZSCAN1	7 interactors: CASK CIC CREB1 RERE TAF7 USP7 ZZZ3
Entrez ID		6879	10346
HPRD ID		07196	05951
Ensembl ID		ENSG00000178913	ENSG00000132274
Uniprot IDs		Q15545	B4DQS5 Q8IYM9
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Transcription From RNA Polymerase II Promoter Viral Process RNA Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Transcription, DNA-templated RNA Metabolic Process DNA-templated Transcription, Initiation Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Histone Acetylation Internal Peptidyl-lysine Acetylation Cellular Metabolic Process Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Peptidyl-lysine Modification Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Histone Modification Histone H3 Acetylation Chromatin Organization Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification Positive Regulation Of Metabolic Process Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Viral Transcription Cellular Response To Stress Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Peptidyl-amino Acid Modification	Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Lung Alveolus Development Lactation Transcription, DNA-templated RNA Biosynthetic Process Protein Stabilization Spermine Transport Regulation Of Metabolic Process Body Fluid Secretion Regulation Of Protein Stability RNA Metabolic Process Chromatin Organization Regulation Of Transcription From RNA Polymerase II Promoter Mammary Gland Development Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Maintenance Of DNA Methylation Lung Development Respiratory Tube Development Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription By Competitive Promoter Binding Cellular Metabolic Process Respiratory System Development Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Keratinocyte Proliferation Lung Saccule Development Positive Regulation Of Calcium Ion Import Multicellular Organismal Development Cellular Response To Zinc Ion Type I Pneumocyte Differentiation Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Intracellular Estrogen Receptor Signaling Pathway Histone Deubiquitination
Tagcloud ?		3d acetyltransferase acetyltransferases architecture assembly cofolding displays dissociable ensures heterodimer integral lys27 machinery mark marks multiprotein neighboring nucleates obvious pic pockets preinitiation reading similarities taf1 tata tfiid trimethylated	addresses bisulfite blotting breast clonogenic correlates de genotoxic greatly h1299 hypermethylation inducible instead leukemic lines malignant mammary monoclonal motif negatively notion null p53 panel relapse similarly supported tripartite wilms
Tagcloud (Difference) ?		3d acetyltransferase acetyltransferases architecture assembly cofolding displays dissociable ensures heterodimer integral lys27 machinery mark marks multiprotein neighboring nucleates obvious pic pockets preinitiation reading similarities taf1 tata tfiid trimethylated	addresses bisulfite blotting breast clonogenic correlates de genotoxic greatly h1299 hypermethylation inducible instead leukemic lines malignant mammary monoclonal motif negatively notion null p53 panel relapse similarly supported tripartite wilms
Tagcloud (Intersection) ?